Viewing rare conformations of the β2 adrenergic receptor with pressure-resolved DEER spectroscopy.
Proceedings Of The National Academy Of Sciences Of The United States Of America
Lerch, Michael T MT; Matt, Rachel A RA; Masureel, Matthieu M; Elgeti, Matthias M; Kumar, Kaavya Krishna KK; Hilger, Daniel D; Foys, Bryon B; Kobilka, Brian K BK; Hubbell, Wayne L WL
Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation.
Nature
Staus, Dean P DP; Strachan, Ryan T RT; Manglik, Aashish A; Pani, Biswaranjan B; Kahsai, Alem W AW; Kim, Tae Hun TH; Wingler, Laura M LM; Ahn, Seungkirl S; Chatterjee, Arnab A; Masoudi, Ali A; Kruse, Andrew C AC; Pardon, Els E; Steyaert, Jan J; Weis, William I WI; Prosser, R Scott RS; Kobilka, Brian K BK; Costa, Tommaso T; Lefkowitz, Robert J RJ