Development and validation of a multivariable genotype-informed gestational diabetes prediction algorithm for clinical use in the Mexican population: insights into susceptibility mechanisms.
Bmj Open Diabetes Research & Care
Zulueta, Mirella M; Gallardo-Rincón, Héctor H; Martinez-Juarez, Luis Alberto LA; Lomelin-Gascon, Julieta J; Ortega-Montiel, Janinne J; Montoya, Alejandra A; Mendizabal, Leire L; Arregi, Maddi M; Martinez-Martinez, María de Los Angeles MLA; Camarillo Romero, Eneida Del Socorro EDS; Mendieta Zerón, Hugo H; Garduño García, José de Jesús JJ; Simón, Laureano L; Tapia-Conyer, Roberto R
Polymorphisms in glucose homeostasis genes are associated with cardiovascular and renal parameters in patients with diabetic nephropathy.
Annals Of Medicine
Mota-Zamorano, Sonia S; González, Luz M LM; Robles, Nicolás R NR; Valdivielso, José M JM; Arévalo-Lorido, José C JC; López-Gómez, Juan J; Gervasini, Guillermo G
Genetic variants for prediction of gestational diabetes mellitus and modulation of susceptibility by a nutritional intervention based on a Mediterranean diet.
Frontiers In Endocrinology
Ramos-Levi, Ana A; Barabash, Ana A; Valerio, Johanna J; García de la Torre, Nuria N; Mendizabal, Leire L; Zulueta, Mirella M; de Miguel, Maria Paz MP; Diaz, Angel A; Duran, Alejandra A; Familiar, Cristina C; Jimenez, Inés I; Del Valle, Laura L; Melero, Veronica V; Moraga, Inmaculada I; Herraiz, Miguel A MA; Torrejon, María José MJ; Arregi, Maddi M; Simón, Laureano L; Rubio, Miguel A MA; Calle-Pascual, Alfonso L AL
Type 2 Diabetes-Related Variants Influence the Risk of Developing Prostate Cancer: A Population-Based Case-Control Study and Meta-Analysis.
Cancers
Sánchez-Maldonado, José Manuel JM; Collado, Ricardo R; Cabrera-Serrano, Antonio José AJ; Ter Horst, Rob R; Gálvez-Montosa, Fernando F; Robles-Fernández, Inmaculada I; Arenas-Rodríguez, Verónica V; Cano-Gutiérrez, Blanca B; Bakker, Olivier O; Bravo-Fernández, María Inmaculada MI; García-Verdejo, Francisco José FJ; López, José Antonio López JAL; Olivares-Ruiz, Jesús J; López-Nevot, Miguel Ángel MÁ; Fernández-Puerta, Laura L; Cózar-Olmo, José Manuel JM; Li, Yang Y; Netea, Mihai G MG; Jurado, Manuel M; Lorente, Jose Antonio JA; Sánchez-Rovira, Pedro P; Álvarez-Cubero, María Jesús MJ; Sainz, Juan J
Association of single nucleotide polymorphisms with insulin secretion, insulin sensitivity, and diabetes in women with a history of gestational diabetes mellitus.
Bmc Medical Genomics
Prasad, Rashmi B RB; Kristensen, Karl K; Katsarou, Anastasia A; Shaat, Nael N
Association of single nucleotide polymorphisms with insulin secretion, insulin sensitivity, and diabetes in women with a history of gestational diabetes mellitus.
Bmc Medical Genomics
Prasad, Rashmi B RB; Kristensen, Karl K; Katsarou, Anastasia A; Shaat, Nael N
All thresholds of maternal hyperglycaemia from the WHO 2013 criteria for gestational diabetes identify women with a higher genetic risk for type 2 diabetes.
Wellcome Open Research
Hughes, Alice E AE; Hayes, M Geoffrey MG; Egan, Aoife M AM; Patel, Kashyap A KA; Scholtens, Denise M DM; Lowe, Lynn P LP; Lowe, William L WL; Dunne, Fidelma P FP; Hattersley, Andrew T AT; Freathy, Rachel M RM
Genome-Wide Association Study of Serum Fructosamine and Glycated Albumin in Adults Without Diagnosed Diabetes: Results From the Atherosclerosis Risk in Communities Study.
Diabetes
Loomis, Stephanie J SJ; Li, Man M; Maruthur, Nisa M NM; Baldridge, Abigail S AS; North, Kari E KE; Mei, Hao H; Morrison, Alanna A; Carson, April P AP; Pankow, James S JS; Boerwinkle, Eric E; Scharpf, Robert R; Rasmussen-Torvik, Laura J LJ; Coresh, Josef J; Duggal, Priya P; Köttgen, Anna A; Selvin, Elizabeth E
Sugar-sweetened beverage intake associations with fasting glucose and insulin concentrations are not modified by selected genetic variants in a ChREBP-FGF21 pathway: a meta-analysis.
Diabetologia
McKeown, Nicola M NM; Dashti, Hassan S HS; Ma, Jiantao J; Haslam, Danielle E DE; Kiefte-de Jong, Jessica C JC; Smith, Caren E CE; Tanaka, Toshiko T; Graff, Mariaelisa M; Lemaitre, Rozenn N RN; Rybin, Denis D; Sonestedt, Emily E; Frazier-Wood, Alexis C AC; Mook-Kanamori, Dennis O DO; Li, Yanping Y; Wang, Carol A CA; Leermakers, Elisabeth T M ETM; Mikkilä, Vera V; Young, Kristin L KL; Mukamal, Kenneth J KJ; Cupples, L Adrienne LA; Schulz, Christina-Alexandra CA; Chen, Tzu-An TA; Li-Gao, Ruifang R; Huang, Tao T; Oddy, Wendy H WH; Raitakari, Olli O; Rice, Kenneth K; Meigs, James B JB; Ericson, Ulrika U; Steffen, Lyn M LM; Rosendaal, Frits R FR; Hofman, Albert A; Kähönen, Mika M; Psaty, Bruce M BM; Brunkwall, Louise L; Uitterlinden, Andre G AG; Viikari, Jorma J; Siscovick, David S DS; Seppälä, Ilkka I; North, Kari E KE; Mozaffarian, Dariush D; Dupuis, Josée J; Orho-Melander, Marju M; Rich, Stephen S SS; de Mutsert, Renée R; Qi, Lu L; Pennell, Craig E CE; Franco, Oscar H OH; Lehtimäki, Terho T; Herman, Mark A MA
Genome-wide association study of 1,5-anhydroglucitol identifies novel genetic loci linked to glucose metabolism.
Scientific Reports
Li, Man M; Maruthur, Nisa M NM; Loomis, Stephanie J SJ; Pietzner, Maik M; North, Kari E KE; Mei, Hao H; Morrison, Alanna C AC; Friedrich, Nele N; Pankow, James S JS; Nauck, Matthias M; Boerwinkle, Eric E; Teumer, Alexander A; Selvin, Elizabeth E; Köttgen, Anna A
Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.
Genome Medicine
Nagy, Reka R; Boutin, Thibaud S TS; Marten, Jonathan J; Huffman, Jennifer E JE; Kerr, Shona M SM; Campbell, Archie A; Evenden, Louise L; Gibson, Jude J; Amador, Carmen C; Howard, David M DM; Navarro, Pau P; Morris, Andrew A; Deary, Ian J IJ; Hocking, Lynne J LJ; Padmanabhan, Sandosh S; Smith, Blair H BH; Joshi, Peter P; Wilson, James F JF; Hastie, Nicholas D ND; Wright, Alan F AF; McIntosh, Andrew M AM; Porteous, David J DJ; Haley, Chris S CS; Vitart, Veronique V; Hayward, Caroline C
Evaluating the transferability of 15 European-derived fasting plasma glucose SNPs in Mexican children and adolescents.
Scientific Reports
Langlois, Christine C; Abadi, Arkan A; Peralta-Romero, Jesus J; Alyass, Akram A; Suarez, Fernando F; Gomez-Zamudio, Jaime J; Burguete-Garcia, Ana I AI; Yazdi, Fereshteh T FT; Cruz, Miguel M; Meyre, David D
A common variant within the HNF1B gene is associated with overall survival of multiple myeloma patients: results from the IMMEnSE consortium and meta-analysis.
Oncotarget
Ríos-Tamayo, Rafael R; Lupiañez, Carmen Belén CB; Campa, Daniele D; Hielscher, Thomas T; Weinhold, Niels N; Martínez-López, Joaquin J; Jerez, Andrés A; Landi, Stefano S; Jamroziak, Krzysztof K; Dumontet, Charles C; Wątek, Marzena M; Lesueur, Fabienne F; Reis, Rui Manuel RM; Marques, Herlander H; Jurczyszyn, Artur A; Vogel, Ulla U; Buda, Gabriele G; García-Sanz, Ramón R; Orciuolo, Enrico E; Petrini, Mario M; Vangsted, Annette J AJ; Gemignani, Federica F; Försti, Asta A; Goldschmidt, Hartmut H; Hemminki, Kari K; Canzian, Federico F; Jurado, Manuel M; Sainz, Juan J
Type 2 Diabetes Risk Allele Loci in the Qatari Population.
Plos One
O'Beirne, Sarah L SL; Salit, Jacqueline J; Rodriguez-Flores, Juan L JL; Staudt, Michelle R MR; Abi Khalil, Charbel C; Fakhro, Khalid A KA; Robay, Amal A; Ramstetter, Monica D MD; Al-Azwani, Iman K IK; Malek, Joel A JA; Zirie, Mahmoud M; Jayyousi, Amin A; Badii, Ramin R; Al-Nabet Al-Marri, Ajayeb A; Chiuchiolo, Maria J MJ; Al-Shakaki, Alya A; Chidiac, Omar O; Gharbiah, Maey M; Bener, Abdulbari A; Stadler, Dora D; Hackett, Neil R NR; Mezey, Jason G JG; Crystal, Ronald G RG
Obesity and associated lifestyles modify the effect of glucose metabolism-related genetic variants on impaired glucose homeostasis among postmenopausal women.
Genetic Epidemiology
Jung, Su Yon SY; Sobel, Eric M EM; Papp, Jeanette C JC; Crandall, Carolyn J CJ; Fu, Alan N AN; Zhang, Zuo-Feng ZF
Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism.
Proceedings Of The National Academy Of Sciences Of The United States Of America
Fadista, João J; Vikman, Petter P; Laakso, Emilia Ottosson EO; Mollet, Inês Guerra IG; Esguerra, Jonathan Lou JL; Taneera, Jalal J; Storm, Petter P; Osmark, Peter P; Ladenvall, Claes C; Prasad, Rashmi B RB; Hansson, Karin B KB; Finotello, Francesca F; Uvebrant, Kristina K; Ofori, Jones K JK; Di Camillo, Barbara B; Krus, Ulrika U; Cilio, Corrado M CM; Hansson, Ola O; Eliasson, Lena L; Rosengren, Anders H AH; Renström, Erik E; Wollheim, Claes B CB; Groop, Leif L
Association of common genetic variants with diabetes and metabolic syndrome related traits in the Arizona Insulin Resistance registry: a focus on Mexican American families in the Southwest.
Human Heredity
DeMenna, Jacob J; Puppala, Sobha S; Chittoor, Geetha G; Schneider, Jennifer J; Kim, Joon Young JY; Shaibi, Gabriel Q GQ; Mandarino, Lawrence J LJ; Duggirala, Ravindranath R; Coletta, Dawn K DK
Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants.
Nature Genetics
Pasquali, Lorenzo L; Gaulton, Kyle J KJ; Rodríguez-Seguí, Santiago A SA; Mularoni, Loris L; Miguel-Escalada, Irene I; Akerman, İldem İ; Tena, Juan J JJ; Morán, Ignasi I; Gómez-Marín, Carlos C; van de Bunt, Martijn M; Ponsa-Cobas, Joan J; Castro, Natalia N; Nammo, Takao T; Cebola, Inês I; García-Hurtado, Javier J; Maestro, Miguel Angel MA; Pattou, François F; Piemonti, Lorenzo L; Berney, Thierry T; Gloyn, Anna L AL; Ravassard, Philippe P; Skarmeta, José Luis Gómez JLG; Müller, Ferenc F; McCarthy, Mark I MI; Ferrer, Jorge J
PROX1 gene variant is associated with fasting glucose change after antihypertensive treatment.
Pharmacotherapy
Gong, Yan Y; McDonough, Caitrin W CW; Beitelshees, Amber L AL; Karnes, Jason H JH; O'Connell, Jeffrey R JR; Turner, Stephen T ST; Chapman, Arlene B AB; Gums, John G JG; Bailey, Kent R KR; Boerwinkle, Eric E; Johnson, Julie A JA; Cooper-DeHoff, Rhonda M RM
Meta-analysis investigating associations between healthy diet and fasting glucose and insulin levels and modification by loci associated with glucose homeostasis in data from 15 cohorts.
American Journal Of Epidemiology
Nettleton, Jennifer A JA; Hivert, Marie-France MF; Lemaitre, Rozenn N RN; McKeown, Nicola M NM; Mozaffarian, Dariush D; Tanaka, Toshiko T; Wojczynski, Mary K MK; Hruby, Adela A; Djoussé, Luc L; Ngwa, Julius S JS; Follis, Jack L JL; Dimitriou, Maria M; Ganna, Andrea A; Houston, Denise K DK; Kanoni, Stavroula S; Mikkilä, Vera V; Manichaikul, Ani A; Ntalla, Ioanna I; Renström, Frida F; Sonestedt, Emily E; van Rooij, Frank J A FJ; Bandinelli, Stefania S; de Koning, Lawrence L; Ericson, Ulrika U; Hassanali, Neelam N; Kiefte-de Jong, Jessica C JC; Lohman, Kurt K KK; Raitakari, Olli O; Papoutsakis, Constantina C; Sjogren, Per P; Stirrups, Kathleen K; Ax, Erika E; Deloukas, Panos P; Groves, Christopher J CJ; Jacques, Paul F PF; Johansson, Ingegerd I; Liu, Yongmei Y; McCarthy, Mark I MI; North, Kari K; Viikari, Jorma J; Zillikens, M Carola MC; Dupuis, Josée J; Hofman, Albert A; Kolovou, Genovefa G; Mukamal, Kenneth K; Prokopenko, Inga I; Rolandsson, Olov O; Seppälä, Ilkka I; Cupples, L Adrienne LA; Hu, Frank B FB; Kähönen, Mika M; Uitterlinden, André G AG; Borecki, Ingrid B IB; Ferrucci, Luigi L; Jacobs, David R DR; Kritchevsky, Stephen B SB; Orho-Melander, Marju M; Pankow, James S JS; Lehtimäki, Terho T; Witteman, Jacqueline C M JC; Ingelsson, Erik E; Siscovick, David S DS; Dedoussis, George G; Meigs, James B JB; Franks, Paul W PW
Genetic variant SLC2A2 [corrected] Is associated with risk of cardiovascular disease – assessing the individual and cumulative effect of 46 type 2 diabetes related genetic variants.
Plos One
Borglykke, Anders A; Grarup, Niels N; Sparsø, Thomas T; Linneberg, Allan A; Fenger, Mogens M; Jeppesen, Jørgen J; Hansen, Torben T; Pedersen, Oluf O; Jørgensen, Torben T
Maternal and offspring fasting glucose and type 2 diabetes-associated genetic variants and cognitive function at age 8: a Mendelian randomization study in the Avon Longitudinal Study of Parents and Children.
Bmc Medical Genetics
Bonilla, Carolina C; Lawlor, Debbie A DA; Ben-Shlomo, Yoav Y; Ness, Andrew R AR; Gunnell, David D; Ring, Susan M SM; Smith, George Davey GD; Lewis, Sarah J SJ
Effects of genetic variants previously associated with fasting glucose and insulin in the Diabetes Prevention Program.
Plos One
Florez, Jose C JC; Jablonski, Kathleen A KA; McAteer, Jarred B JB; Franks, Paul W PW; Mason, Clinton C CC; Mather, Kieren K; Horton, Edward E; Goldberg, Ronald R; Dabelea, Dana D; Kahn, Steven E SE; Arakaki, Richard F RF; Shuldiner, Alan R AR; Knowler, William C WC; ,
Transferability and fine-mapping of glucose and insulin quantitative trait loci across populations: CARe, the Candidate Gene Association Resource.
Diabetologia
Liu, C-T CT; Ng, M C Y MC; Rybin, D D; Adeyemo, A A; Bielinski, S J SJ; Boerwinkle, E E; Borecki, I I; Cade, B B; Chen, Y D I YD; Djousse, L L; Fornage, M M; Goodarzi, M O MO; Grant, S F A SF; Guo, X X; Harris, T T; Kabagambe, E E; Kizer, J R JR; Liu, Y Y; Lunetta, K L KL; Mukamal, K K; Nettleton, J A JA; Pankow, J S JS; Patel, S R SR; Ramos, E E; Rasmussen-Torvik, L L; Rich, S S SS; Rotimi, C N CN; Sarpong, D D; Shriner, D D; Sims, M M; Zmuda, J M JM; Redline, S S; Kao, W H WH; Siscovick, D D; Florez, J C JC; Rotter, J I JI; Dupuis, J J; Wilson, J G JG; Bowden, D W DW; Meigs, J B JB
Reduced insulin exocytosis in human pancreatic β-cells with gene variants linked to type 2 diabetes.
Diabetes
Rosengren, Anders H AH; Braun, Matthias M; Mahdi, Taman T; Andersson, Sofia A SA; Travers, Mary E ME; Shigeto, Makoto M; Zhang, Enming E; Almgren, Peter P; Ladenvall, Claes C; Axelsson, Annika S AS; Edlund, Anna A; Pedersen, Morten Gram MG; Jonsson, Anna A; Ramracheya, Reshma R; Tang, Yunzhao Y; Walker, Jonathan N JN; Barrett, Amy A; Johnson, Paul R V PR; Lyssenko, Valeriya V; McCarthy, Mark I MI; Groop, Leif L; Salehi, Albert A; Gloyn, Anna L AL; Renström, Erik E; Rorsman, Patrik P; Eliasson, Lena L
Glucose-raising genetic variants in MADD and ADCY5 impair conversion of proinsulin to insulin.
Plos One
Wagner, Robert R; Dudziak, Katarzyna K; Herzberg-Schäfer, Silke A SA; Machicao, Fausto F; Stefan, Norbert N; Staiger, Harald H; Häring, Hans-Ulrich HU; Fritsche, Andreas A
Total zinc intake may modify the glucose-raising effect of a zinc transporter (SLC30A8) variant: a 14-cohort meta-analysis.
Diabetes
Kanoni, Stavroula S; Nettleton, Jennifer A JA; Hivert, Marie-France MF; Ye, Zheng Z; van Rooij, Frank J A FJ; Shungin, Dmitry D; Sonestedt, Emily E; Ngwa, Julius S JS; Wojczynski, Mary K MK; Lemaitre, Rozenn N RN; Gustafsson, Stefan S; Anderson, Jennifer S JS; Tanaka, Toshiko T; Hindy, George G; Saylor, Georgia G; Renstrom, Frida F; Bennett, Amanda J AJ; van Duijn, Cornelia M CM; Florez, Jose C JC; Fox, Caroline S CS; Hofman, Albert A; Hoogeveen, Ron C RC; Houston, Denise K DK; Hu, Frank B FB; Jacques, Paul F PF; Johansson, Ingegerd I; Lind, Lars L; Liu, Yongmei Y; McKeown, Nicola N; Ordovas, Jose J; Pankow, James S JS; Sijbrands, Eric J G EJ; Syvänen, Ann-Christine AC; Uitterlinden, André G AG; Yannakoulia, Mary M; Zillikens, M Carola MC; , ; Wareham, Nick J NJ; Prokopenko, Inga I; Bandinelli, Stefania S; Forouhi, Nita G NG; Cupples, L Adrienne LA; Loos, Ruth J RJ; Hallmans, Goran G; Dupuis, Josée J; Langenberg, Claudia C; Ferrucci, Luigi L; Kritchevsky, Stephen B SB; McCarthy, Mark I MI; Ingelsson, Erik E; Borecki, Ingrid B IB; Witteman, Jacqueline C M JC; Orho-Melander, Marju M; Siscovick, David S DS; Meigs, James B JB; Franks, Paul W PW; Dedoussis, George V GV
Association of genetic Loci with glucose levels in childhood and adolescence: a meta-analysis of over 6,000 children.
Diabetes
Barker, Adam A; Sharp, Stephen J SJ; Timpson, Nicholas J NJ; Bouatia-Naji, Nabila N; Warrington, Nicole M NM; Kanoni, Stavroula S; Beilin, Lawrence J LJ; Brage, Soren S; Deloukas, Panos P; Evans, David M DM; Grontved, Anders A; Hassanali, Neelam N; Lawlor, Deborah A DA; Lecoeur, Cecile C; Loos, Ruth J F RJ; Lye, Stephen J SJ; McCarthy, Mark I MI; Mori, Trevor A TA; Ndiaye, Ndeye Coumba NC; Newnham, John P JP; Ntalla, Ioanna I; Pennell, Craig E CE; St Pourcain, Beate B; Prokopenko, Inga I; Ring, Susan M SM; Sattar, Naveed N; Visvikis-Siest, Sophie S; Dedoussis, George V GV; Palmer, Lyle J LJ; Froguel, Philippe P; Smith, George Davey GD; Ekelund, Ulf U; Wareham, Nicholas J NJ; Langenberg, Claudia C
Effects of 34 risk loci for type 2 diabetes or hyperglycemia on lipoprotein subclasses and their composition in 6,580 nondiabetic Finnish men.
Diabetes
Stančáková, Alena A; Paananen, Jussi J; Soininen, Pasi P; Kangas, Antti J AJ; Bonnycastle, Lori L LL; Morken, Mario A MA; Collins, Francis S FS; Jackson, Anne U AU; Boehnke, Michael L ML; Kuusisto, Johanna J; Ala-Korpela, Mika M; Laakso, Markku M