Publications:

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The Role of Krüppel-like Factors in Pancreatic Physiology and Pathophysiology.

International Journal Of Molecular Sciences

Giarrizzo, Michael M; LaComb, Joseph F JF; Bialkowska, Agnieszka B AB

Publication Date: 2023-05-11

Variant appearance in text: PI3K: G12D

PubMed Link: 37239940

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• Main text
• ijms-24-08589.pdf

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AhR and Wnt/β-Catenin Signaling Pathways and Their Interplay.

Current Issues In Molecular Biology

Grishanova, Alevtina Y AY; Klyushova, Lyubov S LS; Perepechaeva, Maria L ML

Publication Date: 2023-05-02

Variant appearance in text: PI3K: G12D

PubMed Link: 37232717

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Adjustable extracellular matrix rigidity tumor model for studying stiffness dependent pancreatic ductal adenocarcinomas progression and tumor immunosuppression.

Bioengineering & Translational Medicine

Zhang, Haoxiang H; Chen, Jiaoshun J; Hu, Xiaoqing X; Bai, Jianwei J; Yin, Tao T

Publication Date: 2023-05

Variant appearance in text: PI3K: G12D

PubMed Link: 37206224

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• Main text
• BTM2-8-e10518.pdf

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Reciprocal Regulation of Cancer-Associated Fibroblasts and Tumor Microenvironment in Gastrointestinal Cancer: Implications for Cancer Dormancy.

Cancers

Cheng, Shih-Hsuan SH; Chiou, Hsin-Ying Clair HC; Wang, Jiunn-Wei JW; Lin, Ming-Hong MH

Publication Date: 2023-04-27

Variant appearance in text: PI3K: G12D

PubMed Link: 37173977

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• Main text

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Epigenetic regulation of stem cells in lung cancer oncogenesis and therapy resistance.

Frontiers In Genetics

Wu, Jiayang J; Feng, Jiaming J; Zhang, Qiran Q; He, Yazhou Y; Xu, Chuan C; Wang, Chengdi C; Li, Weimin W

Publication Date: 2023

Variant appearance in text: PIK3CA: G12D

PubMed Link: 37144123

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Ecological niches for colorectal cancer stem cell survival and thrival.

Frontiers In Oncology

Che, Jiayun J; Yu, Shiyan S

Publication Date: 2023

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PubMed Link: 37124519

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Familial CCM Genes Might Not Be Main Drivers for Pathogenesis of Sporadic CCMs-Genetic Similarity between Cancers and Vascular Malformations.

Journal Of Personalized Medicine

Zhang, Jun J; Croft, Jacob J; Le, Alexander A

Publication Date: 2023-04-17

Variant appearance in text: PI3K: G12D

PubMed Link: 37109059

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• jpm-13-00673.pdf

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Genomic profiling of idiopathic peri-hilar cholangiocarcinoma reveals new targets and mutational pathways.

Scientific Reports

Quinn, Leonard M LM; Haldenby, Sam S; Antzcak, Philip P; Fowler, Anna A; Bullock, Katie K; Kenny, John J; Gilbert, Timothy T; Andrews, Timothy T; Diaz-Nieto, Rafael R; Fenwick, Stephen S; Jones, Robert R; Costello-Goldring, Eithne E; Poston, Graeme G; Greenhalf, William W; Palmer, Daniel D; Malik, Hassan H; Goldring, Chris C

Publication Date: 2023-04-24

Variant appearance in text: PIK3CA: 35G>A; Gly12Asp

PubMed Link: 37095160

Variant Present in the following documents:

• 41598_2023_Article_33096.pdf

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IOA-244 is a Non-ATP-competitive, Highly Selective, Tolerable PI3K Delta Inhibitor That Targets Solid Tumors and Breaks Immune Tolerance.

Cancer Research Communications

Johnson, Zoë Z; Tarantelli, Chiara C; Civanelli, Elisa E; Cascione, Luciano L; Spriano, Filippo F; Fraser, Amy A; Shah, Pritom P; Nomanbhoy, Tyzoon T; Napoli, Sara S; Rinaldi, Andrea A; Niewola-Staszkowska, Karolina K; Lahn, Michael M; Perrin, Dominique D; Wenes, Mathias M; Migliorini, Denis D; Bertoni, Francesco F; van der Veen, Lars L; Di Conza, Giusy G

Publication Date: 2023-04

Variant appearance in text: PI3K: G12D

PubMed Link: 37066023

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• Main text
• crc-22-0477.pdf

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Heterogeneous pattern of gene expression driven by TTN mutation is involved in the construction of a prognosis model of lung squamous cell carcinoma.

Frontiers In Oncology

Liu, Zhao Z; Zhao, Xiaowen X; Wang, Ruihong R; Tang, Xiangyue X; Zhao, Yuxiang Y; Zhong, Guanghui G; Peng, Xin X; Zhang, Chunlin C

Publication Date: 2023

Variant appearance in text: PIK3CA: G12D

PubMed Link: 37035196

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• fonc-13-916568.pdf

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Plasma ctDNA increases tissue NGS-based detection of therapeutically targetable mutations in lung cancers.

Bmc Cancer

Xie, Jianjiang J; Yao, Weishen W; Chen, Lingxiu L; Zhu, Wenjun W; Liu, Qiang Q; Geng, Geng G; Fang, Jing J; Zhao, Yang Y; Xiao, Li L; Huang, Zhenhua Z; Zhao, Jing J

Publication Date: 2023-03-31

Variant appearance in text: PIK3CA: Gly12Asp

PubMed Link: 37004022

Variant Present in the following documents:

• 12885_2023_Article_10674.pdf

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Knocking-Down CD147/EMMPRIN Expression in CT26 Colon Carcinoma Forces the Cells into Cellular and Angiogenic Dormancy That Can Be Reversed by Interactions with Macrophages.

Biomedicines

Feigelman, Gabriele G; Simanovich, Elina E; Brockmeyer, Phillipp P; Rahat, Michal A MA

Publication Date: 2023-03-02

Variant appearance in text: PI3K: G12D

PubMed Link: 36979746

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Atherosclerosis is a smooth muscle cell-driven tumor-like disease.

Biorxiv : The Preprint Server For Biology

Pan, Huize H; Ho, Sebastian E SE; Xue, Chenyi C; Cui, Jian J; Ross, Leila S LS; Li, Fang F; Solomon, Robert A RA; Connolly, E Sander ES; Reilly, Muredach P MP

Publication Date: 2023-03-07

Variant appearance in text: PI3K: G12D

PubMed Link: 36945644

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• media-1.pdf

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The versatile roles of testrapanins in cancer from intracellular signaling to cell-cell communication: cell membrane proteins without ligands.

Cell & Bioscience

Zhou, Zhihang Z; Yang, Zihan Z; Zhou, Li L; Yang, Mengsu M; He, Song S

Publication Date: 2023-03-20

Variant appearance in text: PI3K: G12D

PubMed Link: 36941633

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Spontaneously evolved progenitor niches escape Yap oncogene addiction in advanced pancreatic ductal adenocarcinomas.

Nature Communications

Murakami, Shigekazu S; White, Shannon M SM; McIntosh, Alec T AT; Nguyen, Chan D K CDK; Yi, Chunling C

Publication Date: 2023-03-15

Variant appearance in text: PI3K: G12D

PubMed Link: 36922511

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• Main text
• 41467_2023_Article_37147.pdf

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Rapamycin-Induced Feedback Activation of eIF4E-EIF4A Dependent mRNA Translation in Pancreatic Cancer.

Cancers

Nguyen, Trang Uyen TU; Hector, Harrison H; Pederson, Eric Nels EN; Lin, Jianan J; Ouyang, Zhengqing Z; Wendel, Hans-Guido HG; Singh, Kamini K

Publication Date: 2023-02-24

Variant appearance in text: PI3K: G12D

PubMed Link: 36900235

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• cancers-15-01444.pdf

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UPLC-MS based integrated plasma proteomic and metabolomic profiling of TSC-RAML and its relationship with everolimus treatment.

Frontiers In Molecular Biosciences

Wang, Zhan Z; Liu, Xiaoyan X; Wang, Wenda W; Xu, Jiyu J; Sun, Haidan H; Wei, Jing J; Yu, Yuncui Y; Zhao, Yang Y; Wang, Xu X; Liao, Zhangcheng Z; Sun, Wei W; Jia, Lulu L; Zhang, Yushi Y

Publication Date: 2023

Variant appearance in text: PI3K: G12D

PubMed Link: 36891236

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• fmolb-10-1000248.pdf

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Involvement of redox signalling in tumour cell dormancy and metastasis.

Cancer Metastasis Reviews

Puente-Cobacho, Beatriz B; Varela-López, Alfonso A; Quiles, José L JL; Vera-Ramirez, Laura L

Publication Date: 2023-01-26

Variant appearance in text: PI3K: G12D

PubMed Link: 36701089

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Single-Cell Analysis of Circulating Tumor Cells from Patients with Colorectal Cancer Captured with a Dielectrophoresis-Based Micropore System.

Biomedicines

Nomura, Masatoshi M; Miyake, Yuichiro Y; Inoue, Akira A; Yokoyama, Yuhki Y; Noda, Nanaka N; Kouda, Shihori S; Hata, Tsuyoshi T; Ogino, Takayuki T; Miyoshi, Norikatsu N; Takahashi, Hidekazu H; Uemura, Mamoru M; Mizushima, Tsunekazu T; Doki, Yuichiro Y; Eguchi, Hidetoshi H; Yamamoto, Hirofumi H

Publication Date: 2023-01-13

Variant appearance in text: PIK3CA: G12D

PubMed Link: 36672711

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• biomedicines-11-00203.pdf

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An unconventional cancer-promoting function of methamphetamine in hepatocellular carcinoma.

Life Science Alliance

Si, Zizhen Z; Yang, GuanJun G; Wang, Xidi X; Yu, Zhaoying Z; Pang, Qian Q; Zhang, Shuangshuang S; Qian, Liyin L; Ruan, Yuer Y; Huang, Jing J; Yu, Liu L

Publication Date: 2023-03

Variant appearance in text: PI3K: G12D

PubMed Link: 36669783

Variant Present in the following documents:

• LSA-2022-01660.pdf

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The roles of connexins and gap junctions in the progression of cancer.

Cell Communication And Signaling : Ccs

Zhou, Mingming M; Zheng, Minying M; Zhou, Xinyue X; Tian, Shifeng S; Yang, Xiaohui X; Ning, Yidi Y; Li, Yuwei Y; Zhang, Shiwu S

Publication Date: 2023-01-13

Variant appearance in text: PI3K: G12D

PubMed Link: 36639804

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• Main text
• 12964_2022_Article_1009.pdf

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Preclinical Models of Follicular Cell-Derived Thyroid Cancer: An Overview from Cancer Cell Lines to Mouse Models.

Endocrinology And Metabolism (Seoul, Korea)

Jeon, Min Ji MJ; Haugen, Bryan R BR

Publication Date: 2022-12

Variant appearance in text: PIK3CA: G12D

PubMed Link: 36604954

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• Main text
• enm-2022-1636.pdf

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Genetic landscape of colorectal cancer patients manifesting tumor shrinkage during SARS-Cov-2 infection.

Therapeutic Advances In Medical Oncology

Ottaiano, Alessandro A; Santorsola, Mariachiara M; Circelli, Luisa L; Cascella, Marco M; Petrillo, Nadia N; Perri, Francesco F; Casillo, Marika M; Granata, Vincenza V; Ianniello, Monica M; Izzo, Francesco F; Picone, Carmine C; Correra, Marco M; Petrillo, Antonella A; Sirica, Roberto R; Misso, Gabriella G; Delrio, Paolo P; Nasti, Guglielmo G; Savarese, Giovanni G; Caraglia, Michele M

Publication Date: 2022

Variant appearance in text: PIK3CA: G12D

PubMed Link: 36518158

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Pharmacologic Inhibition of SHP2 Blocks Both PI3K and MEK Signaling in Low-epiregulin HNSCC via GAB1.

Cancer Research Communications

Kurupi, Richard R; Floros, Konstantinos V KV; Jacob, Sheeba S; Chawla, Ayesha T AT; Cai, Jinyang J; Hu, Bin B; Puchalapalli, Madhavi M; Coon, Colin M CM; Khatri, Rishabh R; Crowther, Giovanna Stein GS; Egan, Regina K RK; Murchie, Ellen E; Greninger, Patricia P; Dalton, Krista M KM; Ghotra, Maninderjit S MS; Boikos, Sosipatros A SA; Koblinski, Jennifer E JE; Harada, Hisashi H; Sun, Yue Y; Morgan, Iain M IM; Basu, Devraj D; Dozmorov, Mikhail G MG; Benes, Cyril H CH; Faber, Anthony C AC

Publication Date: 2022-09

Variant appearance in text: PI3K: G12D

PubMed Link: 36506869

Variant Present in the following documents:

• crc-21-0137.pdf

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Review of the endocrine organ-like tumor hypothesis of cancer cachexia in pancreatic ductal adenocarcinoma.

Frontiers In Oncology

Yu, Ying-Chun YC; Ahmed, Azaj A; Lai, Hsueh-Chou HC; Cheng, Wei-Chung WC; Yang, Juan-Chern JC; Chang, Wei-Chun WC; Chen, Lu-Min LM; Shan, Yan-Shen YS; Ma, Wen-Lung WL

Publication Date: 2022

Variant appearance in text: PI3K: G12D

PubMed Link: 36465353

Variant Present in the following documents:

• fonc-12-1057930.pdf

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Case report: Undifferentiated sarcoma with multiple tumors involved in Lynch syndrome: Unexpected favorable outcome to sintilimab combined with chemotherapy.

Frontiers In Oncology

Liu, Jiaying J; Chang, Xiaona X; Xiao, Guixiang G; Zhong, Jingmin J; Huang, Bo B; Zhang, Jiwei J; Gao, Beibei B; Peng, Gang G; Nie, Xiu X

Publication Date: 2022

Variant appearance in text: PIK3CA: G12D

PubMed Link: 36457512

Variant Present in the following documents:

• fonc-12-1014859.pdf

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Mutant Kras and mTOR crosstalk drives hepatocellular carcinoma development via PEG3/STAT3/BEX2 signaling.

Theranostics

Luo, Yuan-Deng YD; Liu, Xiao-Yu XY; Fang, Lei L; Yu, Hong-Qiang HQ; Zhang, Yu-Jun YJ; Chen, Min M; Zhang, Lei-Da LD; Xie, Chuan-Ming CM

Publication Date: 2022

Variant appearance in text: PI3K: G12D

PubMed Link: 36451866

Variant Present in the following documents:

• thnov12p7903.pdf

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Signaling pathways in cancer-associated fibroblasts: recent advances and future perspectives.

Cancer Communications (London, England)

Fang, Zengli Z; Meng, Qingcai Q; Xu, Jin J; Wang, Wei W; Zhang, Bo B; Liu, Jiang J; Liang, Chen C; Hua, Jie J; Zhao, Yingjun Y; Yu, Xianjun X; Shi, Si S

Publication Date: 2022-11-24

Variant appearance in text: PI3K: G12D

PubMed Link: 36424360

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• Main text
• CAC2-43-3.pdf

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Psychological distress and eustress in cancer and cancer treatment: Advances and perspectives.

Science Advances

Wu, Yuanjun Y; Zhou, Laiyan L; Zhang, Xuanwei X; Yang, Xue X; Niedermann, Gabriele G; Xue, Jianxin J

Publication Date: 2022-11-25

Variant appearance in text: PI3K: G12D

PubMed Link: 36417542

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• sciadv.abq7982.pdf

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Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications

Boström, Martin M; Larsson, Erik E

Publication Date: 2022-11-17

Variant appearance in text: PIK3CA: G12D

PubMed Link: 36396655

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• 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1

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The role of KRAS splice variants in cancer biology.

Frontiers In Cell And Developmental Biology

Nuevo-Tapioles, Cristina C; Philips, Mark R MR

Publication Date: 2022

Variant appearance in text: PI3K: G12D

PubMed Link: 36393833

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• fcell-10-1033348.pdf

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Mouse models of Kras activation in gastric cancer.

Experimental & Molecular Medicine

Won, Yoonkyung Y; Choi, Eunyoung E

Publication Date: 2022-11

Variant appearance in text: PIK3CA: G12D

PubMed Link: 36369466

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• Main text
• 12276_2022_Article_882.pdf

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In Vivo Models for Prostate Cancer Research.

Cancers

Adamiecki, Robert R; Hryniewicz-Jankowska, Anita A; Ortiz, Maria A MA; Li, Xiang X; Porter-Hansen, Baylee A BA; Nsouli, Imad I; Bratslavsky, Gennady G; Kotula, Leszek L

Publication Date: 2022-10-28

Variant appearance in text: PI3K: G12D

PubMed Link: 36358740

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• Main text

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From Promise to Reality: Bioengineering Strategies to Enhance the Therapeutic Potential of Extracellular Vesicles.

Bioengineering (Basel, Switzerland)

de Almeida Fuzeta, Miguel M; Gonçalves, Pedro P PP; Fernandes-Platzgummer, Ana A; Cabral, Joaquim M S JMS; Bernardes, Nuno N; da Silva, Cláudia L CL

Publication Date: 2022-11-10

Variant appearance in text: PI3K: G12D

PubMed Link: 36354586

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• Main text

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Omics analyses of a somatic <i>Trp53^R245W/+</i> breast cancer model identify cooperating driver events activating PI3K/AKT/mTOR signaling.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Yu, Xiaojie X; Zhang, Yun Y; Xiong, Shunbin S; McDaniel, Joy M JM; Sun, Chang C; Chau, Gilda P GP; Gencel-Augusto, Jovanka J; Chachad, Dhruv D; Morrissey, Rhiannon L RL; Rao, Xiayu X; Wang, Jing J; Lozano, Guillermina G

Publication Date: 2022-11-08

Variant appearance in text: PI3K: G12D

PubMed Link: 36322759

Variant Present in the following documents:

• pnas.2210618119.sapp.pdf

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Shallow WGS of individual CTCs identifies actionable targets for informing treatment decisions in metastatic breast cancer.

British Journal Of Cancer

Fernandez-Garcia, Daniel D; Nteliopoulos, Georgios G; Hastings, Robert K RK; Rushton, Amelia A; Page, Karen K; Allsopp, Rebecca C RC; Ambasager, Bana B; Gleason, Kelly K; Guttery, David S DS; Ali, Simak S; Charles Coombes, R R; Shaw, Jacqueline A JA

Publication Date: 2022-11

Variant appearance in text: PIK3CA: G12D

PubMed Link: 36088510

Variant Present in the following documents:

• 41416_2022_1962_MOESM2_ESM.xlsx, sheet 4

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Cancer genome and tumor microenvironment: Reciprocal crosstalk shapes lung cancer plasticity.

Elife

Mansouri, Siavash S; Heylmann, Daniel D; Stiewe, Thorsten T; Kracht, Michael M; Savai, Rajkumar R

Publication Date: 2022-09-08

Variant appearance in text: PI3K: G12D

PubMed Link: 36074553

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Targeting senescence as an anticancer therapy.

Molecular Oncology

Bousset, Laura L; Gil, Jesús J

Publication Date: 2022-11

Variant appearance in text: PI3K: G12D

PubMed Link: 36065138

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Tyrosine phosphatase SHP2 in ovarian granulosa cells balances follicular development by inhibiting PI3K/AKT signaling.

Journal Of Molecular Cell Biology

Wei, Xiaoli X; Zheng, Lanping L; Tian, Yingpu Y; Wang, Haibin H; Su, Youqiang Y; Feng, Gensheng G; Wang, Chao C; Lu, Zhongxian Z

Publication Date: 2022-08-24

Variant appearance in text: PI3K: G12D

PubMed Link: 36002018

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Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia.

Cell Stem Cell

Vasquez, Ester Gil EG; Nasreddin, Nadia N; Valbuena, Gabriel N GN; Mulholland, Eoghan J EJ; Belnoue-Davis, Hayley L HL; Eggington, Holly R HR; Schenck, Ryan O RO; Wouters, Valérie M VM; Wirapati, Pratyaksha P; Gilroy, Kathryn K; Lannagan, Tamsin R M TRM; Flanagan, Dustin J DJ; Najumudeen, Arafath K AK; Omwenga, Sulochana S; McCorry, Amy M B AMB; Easton, Alistair A; Koelzer, Viktor H VH; East, James E JE; Morton, Dion D; Trusolino, Livio L; Maughan, Timothy T; Campbell, Andrew D AD; Loughrey, Maurice B MB; Dunne, Philip D PD; Tsantoulis, Petros P; Huels, David J DJ; Tejpar, Sabine S; Sansom, Owen J OJ; Leedham, Simon J SJ

Publication Date: 2022-08-04

Variant appearance in text: PIK3CA: G12D

PubMed Link: 35931031

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Molecular characterization of colorectal cancer related peritoneal metastatic disease.

Nature Communications

Lenos, Kristiaan J KJ; Bach, Sander S; Ferreira Moreno, Leandro L; Ten Hoorn, Sanne S; Sluiter, Nina R NR; Bootsma, Sanne S; Vieira Braga, Felipe A FA; Nijman, Lisanne E LE; van den Bosch, Tom T; Miedema, Daniel M DM; van Dijk, Erik E; Ylstra, Bauke B; Kulicke, Ruth R; Davis, Fred P FP; Stransky, Nicolas N; Smolen, Gromoslaw A GA; Coebergh van den Braak, Robert R J RRJ; IJzermans, Jan N M JNM; Martens, John W M JWM; Hallam, Sally S; Beggs, Andrew D AD; Kops, Geert J P L GJPL; Lansu, Nico N; Bastiaenen, Vivian P VP; Klaver, Charlotte E L CEL; Lecca, Maria C MC; El Makrini, Khalid K; Elbers, Clara C CC; Dings, Mark P G MPG; van Noesel, Carel J M CJM; Kranenburg, Onno O; Medema, Jan Paul JP; Koster, Jan J; Koens, Lianne L; Punt, Cornelis J A CJA; Tanis, Pieter J PJ; de Hingh, Ignace H IH; Bijlsma, Maarten F MF; Tuynman, Jurriaan B JB; Vermeulen, Louis L

Publication Date: 2022-08-04

Variant appearance in text: PIK3CA: G12D

PubMed Link: 35927254

Variant Present in the following documents:

• 41467_2022_32198_MOESM4_ESM.xlsx, sheet 1

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Targeting the Hippo/YAP/TAZ signalling pathway: Novel opportunities for therapeutic interventions into skin cancers.

Experimental Dermatology

Howard, Alexander A; Bojko, Jodie J; Flynn, Benjamin B; Bowen, Sophie S; Jungwirth, Ute U; Walko, Gernot G

Publication Date: 2022-10

Variant appearance in text: PI3K: G12D

PubMed Link: 35913427

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Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Durinikova, Erika E; Reilly, Nicole M NM; Buzo, Kristi K; Mariella, Elisa E; Chilà, Rosaria R; Lorenzato, Annalisa A; Dias, João M L JML; Grasso, Gaia G; Pisati, Federica F; Lamba, Simona S; Corti, Giorgio G; Degasperi, Andrea A; Cancelliere, Carlotta C; Mauri, Gianluca G; Andrei, Pietro P; Linnebacher, Michael M; Marsoni, Silvia S; Siena, Salvatore S; Sartore-Bianchi, Andrea A; Nik-Zainal, Serena S; Di Nicolantonio, Federica F; Bardelli, Alberto A; Arena, Sabrina S

Publication Date: 2022-09-01

Variant appearance in text: PIK3CA: G12D

PubMed Link: 35881546

Variant Present in the following documents:

• EMS151756-supplement-Table_S1.xlsx, sheet 1

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Antibody-mediated blockade for galectin-3 binding protein in tumor secretome abrogates PDAC metastasis.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Choi, Yeon-Sook YS; Kim, Myung Ji MJ; Choi, Eun A EA; Kim, Sinae S; Lee, Eun Ji EJ; Park, Min Ji MJ; Kim, Mi-Ju MJ; Kim, Yeon Wook YW; Ahn, Hee-Sung HS; Jung, Jae Yun JY; Jang, Gayoung G; Kim, Yongsub Y; Kim, Hyori H; Kim, Kyunggon K; Kim, Jin Young JY; Hong, Seung-Mo SM; Kim, Song Cheol SC; Chang, Suhwan S

Publication Date: 2022-07-26

Variant appearance in text: PI3K: G12D

PubMed Link: 35858411

Variant Present in the following documents:

• pnas.202119048.pdf

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Research Progress of Cell Lineage Tracing and Single-Cell Sequencing Technology in Malignant Skin Tumors.

Frontiers In Surgery

Li, Ang A; Liu, Baoyi B; Xu, Jingkai J; Cui, Yong Y

Publication Date: 2022

Variant appearance in text: PIK3CA: G12D

PubMed Link: 35784923

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FBXW7 and the Hallmarks of Cancer: Underlying Mechanisms and Prospective Strategies.

Frontiers In Oncology

Shen, Wenyue W; Zhou, Quanwei Q; Peng, Chenxi C; Li, Jiaheng J; Yuan, Qizhi Q; Zhu, Hecheng H; Zhao, Ming M; Jiang, Xingjun X; Liu, Weidong W; Ren, Caiping C

Publication Date: 2022

Variant appearance in text: PI3K: G12D

PubMed Link: 35515121

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• fonc-12-880077.pdf

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Ibrutinib in the Treatment of Solid Tumors: Current State of Knowledge and Future Directions.

Cells

Szklener, Katarzyna K; Michalski, Adam A; Żak, Klaudia K; Piwoński, Michał M; Mańdziuk, Sławomir S

Publication Date: 2022-04-14

Variant appearance in text: PI3K: G12D

PubMed Link: 35456016

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Mutant p53 achieved Gain-of-Function by promoting tumor growth and immune escape through PHLPP2/AKT/PD-L1 pathway.

International Journal Of Biological Sciences

Liu, Nannan N; Jiang, Xinxiu X; Guo, Leiming L; Zhang, Chuchu C; Jiang, Meimei M; Sun, Zhuoran Z; Zhang, Yizheng Y; Mi, Wunan W; Li, Jiehan J; Fu, Yang Y; Wang, Feng F; Zhang, Lingling L; Zhang, Yingjie Y

Publication Date: 2022

Variant appearance in text: PIK3CA: G12D

PubMed Link: 35414774

Variant Present in the following documents:

• ijbsv18p2419.pdf

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Clinical significance of FBXW7 loss of function in human cancers.

Molecular Cancer

Fan, Jingyi J; Bellon, Marcia M; Ju, Mingyi M; Zhao, Lin L; Wei, Minjie M; Fu, Liwu L; Nicot, Christophe C

Publication Date: 2022-03-26

Variant appearance in text: PI3K: G12D

PubMed Link: 35346215

Variant Present in the following documents:

• 12943_2022_Article_1548.pdf

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[Lung Cancer Stem-like Cells and Drug Resistance].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer

Pan, Zhenhua Z; Liu, Hongyu H; Chen, Jun J

Publication Date: 2022-02-20

Variant appearance in text: PI3K: G12D

PubMed Link: 35224964

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• zgfazz-25-2-111.pdf

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NSAIDs and Cancer Resolution: New Paradigms beyond Cyclooxygenase.

International Journal Of Molecular Sciences

Kolawole, Oluwafunke R OR; Kashfi, Khosrow K

Publication Date: 2022-01-27

Variant appearance in text: PI3K: G12D

PubMed Link: 35163356

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• Main text

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Phase I pharmacokinetic study of single agent trametinib in patients with advanced cancer and hepatic dysfunction.

Journal Of Experimental & Clinical Cancer Research : Cr

Voon, Pei Jye PJ; Chen, Eric X EX; Chen, Helen X HX; Lockhart, Albert C AC; Sahebjam, Solmaz S; Kelly, Karen K; Vaishampayan, Ulka N UN; Subbiah, Vivek V; Razak, Albiruni R AR; Renouf, Daniel J DJ; Hotte, Sebastien J SJ; Singh, Arti A; Bedard, Philippe L PL; Hansen, Aaron R AR; Ivy, S Percy SP; Wang, Lisa L; Stayner, Lee-Anne LA; Siu, Lillian L LL; Spreafico, Anna A

Publication Date: 2022-02-07

Variant appearance in text: PI3K: G12D

PubMed Link: 35130943

Variant Present in the following documents:

• 13046_2021_2236_MOESM3_ESM.pdf

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Phase I pharmacokinetic study of single agent trametinib in patients with advanced cancer and hepatic dysfunction.

Journal Of Experimental & Clinical Cancer Research : Cr

Voon, Pei Jye PJ; Chen, Eric X EX; Chen, Helen X HX; Lockhart, Albert C AC; Sahebjam, Solmaz S; Kelly, Karen K; Vaishampayan, Ulka N UN; Subbiah, Vivek V; Razak, Albiruni R AR; Renouf, Daniel J DJ; Hotte, Sebastien J SJ; Singh, Arti A; Bedard, Philippe L PL; Hansen, Aaron R AR; Ivy, S Percy SP; Wang, Lisa L; Stayner, Lee-Anne LA; Siu, Lillian L LL; Spreafico, Anna A

Publication Date: 2022-02-07

Variant appearance in text: PI3K: G12D

PubMed Link: 35130943

Variant Present in the following documents:

• 13046_2021_2236_MOESM3_ESM.pdf

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Lung cancer A549 cells suppressed with overexpressed HNF1B or PCDHA13 inhibited PI3K/AKT phosphorylation.

Translational Cancer Research

Kang, Chunyan C; Wang, Lingxiao L; Wang, Dandan D; Zhang, Xiuzhi X; Chen, Jie J

Publication Date: 2020-06

Variant appearance in text: PI3K: G12D

PubMed Link: 35117749

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• Main text

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How can same-gene mutations promote both cancer and developmental disorders?

Science Advances

Nussinov, Ruth R; Tsai, Chung-Jung CJ; Jang, Hyunbum H

Publication Date: 2022-01-14

Variant appearance in text: PI3K: G12D

PubMed Link: 35030014

Variant Present in the following documents:

• Main text
• sciadv.abm2059.pdf

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How can same-gene mutations promote both cancer and developmental disorders?

Science Advances

Nussinov, Ruth R; Tsai, Chung-Jung CJ; Jang, Hyunbum H

Publication Date: 2022-01-14

Variant appearance in text: PI3K: G12D

PubMed Link: 35030014

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• Main text
• sciadv.abm2059.pdf

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Overcoming resistance to immune checkpoint therapy in PTEN-null prostate cancer by intermittent anti-PI3Kα/β/δ treatment.

Nature Communications

Qi, Zhi Z; Xu, Zihan Z; Zhang, Liuzhen L; Zou, Yongkang Y; Li, Jinping J; Yan, Wenyu W; Li, Cheng C; Liu, Ningshu N; Wu, Hong H

Publication Date: 2022-01-10

Variant appearance in text: PI3K: G12D

PubMed Link: 35013322

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• Main text

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Ribosomal Protein S6: A Potential Therapeutic Target against Cancer?

International Journal Of Molecular Sciences

Yi, Yong Weon YW; You, Kyu Sic KS; Park, Jeong-Soo JS; Lee, Seok-Geun SG; Seong, Yeon-Sun YS

Publication Date: 2021-12-21

Variant appearance in text: PI3K: G12D

PubMed Link: 35008473

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• Main text

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Ribosomal Protein S6: A Potential Therapeutic Target against Cancer?

International Journal Of Molecular Sciences

Yi, Yong Weon YW; You, Kyu Sic KS; Park, Jeong-Soo JS; Lee, Seok-Geun SG; Seong, Yeon-Sun YS

Publication Date: 2021-12-21

Variant appearance in text: PI3K: G12D

PubMed Link: 35008473

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• Main text

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Autophagy and ncRNAs: Dangerous Liaisons in the Crosstalk between the Tumor and Its Microenvironment.

Cancers

Eng, Gracie Wee Ling GWL; Zheng, Yilong Y; Yap, Dominic Wei Ting DWT; Teo, Andrea York Tiang AYT; Cheong, Jit Kong JK

Publication Date: 2021-12-21

Variant appearance in text: PI3K: G12D

PubMed Link: 35008183

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• Main text

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The clinical significance of adenomatous polyposis coli (APC) and catenin Beta 1 (CTNNB1) genetic aberrations in patients with melanoma.

Bmc Cancer

Karachaliou, Georgia Sofia GS; Alkallas, Rached R; Carroll, Sarah B SB; Caressi, Chongshan C; Zakria, Danny D; Patel, Nirali M NM; Trembath, Dimitri G DG; Ezzell, Jennifer A JA; Pegna, Guillaume J GJ; Googe, Paul B PB; Galeotti, Jonathan P JP; Ayvali, Fatih F; Collichio, Frances A FA; Lee, Carrie B CB; Ollila, David W DW; Gulley, Margaret L ML; Johnson, Douglas B DB; Kim, Kevin B KB; Watson, Ian R IR; Moschos, Stergios J SJ

Publication Date: 2022-01-05

Variant appearance in text: PIK3CA: G12D

PubMed Link: 34986841

Variant Present in the following documents:

• 12885_2021_8908_MOESM2_ESM.xlsx, sheet 2

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The clinical significance of adenomatous polyposis coli (APC) and catenin Beta 1 (CTNNB1) genetic aberrations in patients with melanoma.

Bmc Cancer

Karachaliou, Georgia Sofia GS; Alkallas, Rached R; Carroll, Sarah B SB; Caressi, Chongshan C; Zakria, Danny D; Patel, Nirali M NM; Trembath, Dimitri G DG; Ezzell, Jennifer A JA; Pegna, Guillaume J GJ; Googe, Paul B PB; Galeotti, Jonathan P JP; Ayvali, Fatih F; Collichio, Frances A FA; Lee, Carrie B CB; Ollila, David W DW; Gulley, Margaret L ML; Johnson, Douglas B DB; Kim, Kevin B KB; Watson, Ian R IR; Moschos, Stergios J SJ

Publication Date: 2022-01-05

Variant appearance in text: PIK3CA: G12D

PubMed Link: 34986841

Variant Present in the following documents:

• 12885_2021_8908_MOESM2_ESM.xlsx, sheet 2

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Multicellular Effects of STAT3 in Non-small Cell Lung Cancer: Mechanistic Insights and Therapeutic Opportunities.

Cancers

Parakh, Sagun S; Ernst, Matthias M; Poh, Ashleigh R AR

Publication Date: 2021-12-11

Variant appearance in text: PI3K: G12D

PubMed Link: 34944848

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• Main text

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The developing landscape of combinatorial therapies of immune checkpoint blockade with DNA damage repair inhibitors for the treatment of breast and ovarian cancers.

Journal Of Hematology & Oncology

Zhu, Lingling L; Liu, Jiewei J; Chen, Jiang J; Zhou, Qinghua Q

Publication Date: 2021-12-20

Variant appearance in text: PI3K: G12D

PubMed Link: 34930377

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• Main text
• 13045_2021_Article_1218.pdf

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The developing landscape of combinatorial therapies of immune checkpoint blockade with DNA damage repair inhibitors for the treatment of breast and ovarian cancers.

Journal Of Hematology & Oncology

Zhu, Lingling L; Liu, Jiewei J; Chen, Jiang J; Zhou, Qinghua Q

Publication Date: 2021-12-20

Variant appearance in text: PI3K: G12D

PubMed Link: 34930377

Variant Present in the following documents:

• Main text
• 13045_2021_Article_1218.pdf

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Proteogenomics of non-small cell lung cancer reveals molecular subtypes associated with specific therapeutic targets and immune evasion mechanisms.

Nature Cancer

Lehtiö, Janne J; Arslan, Taner T; Siavelis, Ioannis I; Pan, Yanbo Y; Socciarelli, Fabio F; Berkovska, Olena O; Umer, Husen M HM; Mermelekas, Georgios G; Pirmoradian, Mohammad M; Jönsson, Mats M; Brunnström, Hans H; Brustugun, Odd Terje OT; Purohit, Krishna Pinganksha KP; Cunningham, Richard R; Foroughi Asl, Hassan H; Isaksson, Sofi S; Arbajian, Elsa E; Aine, Mattias M; Karlsson, Anna A; Kotevska, Marija M; Gram Hansen, Carsten C; Drageset Haakensen, Vilde V; Helland, Åslaug Å; Tamborero, David D; Johansson, Henrik J HJ; Branca, Rui M RM; Planck, Maria M; Staaf, Johan J; Orre, Lukas M LM

Publication Date: 2021-11

Variant appearance in text: PIK3CA: 35G>A; Gly12Asp

PubMed Link: 34870237

Variant Present in the following documents:

• EMS133264-supplement-Supplementary_Tables.xlsx, sheet 9

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Melanoma Immunotherapy and Precision Medicine in the Era of Tumor Micro-Tissue Engineering: Where Are We Now and Where Are We Going?

Cancers

Varrone, Francesca F; Mandrich, Luigi L; Caputo, Emilia E

Publication Date: 2021-11-18

Variant appearance in text: PI3K: G12D

PubMed Link: 34830940

Variant Present in the following documents:

• cancers-13-05788.pdf

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