Molecular landscape of TP53 mutations in breast cancer and their utility for predicting the response to HER-targeted therapy in HER2 amplification-positive and HER2 mutation-positive amplification-negative patients.
HGAL inhibits lymphoma dissemination by interacting with multiple cytoskeletal proteins.
Blood Advances
Jiang, Xiaoyu X; Lu, XiaoQing X; Gentles, Andrew J AJ; Zhao, Dekuang D; Wander, Seth A SA; Zhang, Yu Y; Natkunam, Yasodha Y; Slingerland, Joyce J; Reis, Isildinha M IM; Rabinovich, Brian B; Abdulreda, Midhat H MH; Moy, Vincent T VT; Lossos, Izidore S IS
LOVTRAP: an optogenetic system for photoinduced protein dissociation.
Nature Methods
Wang, Hui H; Vilela, Marco M; Winkler, Andreas A; Tarnawski, Miroslaw M; Schlichting, Ilme I; Yumerefendi, Hayretin H; Kuhlman, Brian B; Liu, Rihe R; Danuser, Gaudenz G; Hahn, Klaus M KM
Metabolic/Proteomic Signature Defines Two Glioblastoma Subtypes With Different Clinical Outcome.
Scientific Reports
Marziali, G G; Signore, M M; Buccarelli, M M; Grande, S S; Palma, A A; Biffoni, M M; Rosi, A A; D'Alessandris, Q G QG; Martini, M M; Larocca, L M LM; De Maria, R R; Pallini, R R; Ricci-Vitiani, L L
3-Methylcholanthrene, an AhR agonist, caused cell-cycle arrest by histone deacetylation through a RhoA-dependent recruitment of HDAC1 and pRb2 to E2F1 complex.
Integrin-matrix clusters form podosome-like adhesions in the absence of traction forces.
Cell Reports
Yu, Cheng-han CH; Rafiq, Nisha Bte Mohd NB; Krishnasamy, Anitha A; Hartman, Kevin L KL; Jones, Gareth E GE; Bershadsky, Alexander D AD; Sheetz, Michael P MP
Stimulus-dependent phosphorylation of profilin-1 in angiogenesis.
Nature Cell Biology
Fan, Yi Y; Arif, Abul A; Gong, Yanqing Y; Jia, Jie J; Eswarappa, Sandeepa M SM; Willard, Belinda B; Horowitz, Arie A; Graham, Linda M LM; Penn, Marc S MS; Fox, Paul L PL
Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival.
The Embo Journal
Drosten, Matthias M; Dhawahir, Alma A; Sum, Eleanor Y M EY; Urosevic, Jelena J; Lechuga, Carmen G CG; Esteban, Luis M LM; Castellano, Esther E; Guerra, Carmen C; Santos, Eugenio E; Barbacid, Mariano M
The Sex-determining region Y-box 4 and homeobox C6 transcriptional networks in prostate cancer progression: crosstalk with the Wnt, Notch, and PI3K pathways.
Nck adapters are involved in the formation of dorsal ruffles, cell migration, and Rho signaling downstream of the platelet-derived growth factor beta receptor.
The Journal Of Biological Chemistry
Ruusala, Aino A; Pawson, Tony T; Heldin, Carl-Henrik CH; Aspenström, Pontus P