Publications:

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Comprehensive germline and somatic genomic profiles of Chinese patients with biliary tract cancer.

Frontiers In Oncology

Yu, Haipeng H; Xu, Yan Y; Gao, Wei W; Li, Mei M; He, Ji'an J; Deng, Xiaoqian X; Xing, Wenge W

Publication Date: 2022

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PubMed Link: 36072793

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• Table_3.xlsx, sheet 1

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PepNN: a deep attention model for the identification of peptide binding sites.

Communications Biology

Abdin, Osama O; Nim, Satra S; Wen, Han H; Kim, Philip M PM

Publication Date: 2022-05-26

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PubMed Link: 35618814

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Molecular landscape of TP53 mutations in breast cancer and their utility for predicting the response to HER-targeted therapy in HER2 amplification-positive and HER2 mutation-positive amplification-negative patients.

Cancer Medicine

Liu, Binliang B; Yi, Zongbi Z; Guan, Yanfang Y; Ouyang, Quchang Q; Li, Chunxiao C; Guan, Xiuwen X; Lv, Dan D; Li, Lixi L; Zhai, Jingtong J; Qian, Haili H; Xu, Binghe B; Ma, Fei F; Zeng, Yixin Y

Publication Date: 2022-07

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PubMed Link: 35393784

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• CAM4-11-2767-s001.xlsx, sheet 1

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HGAL inhibits lymphoma dissemination by interacting with multiple cytoskeletal proteins.

Blood Advances

Jiang, Xiaoyu X; Lu, XiaoQing X; Gentles, Andrew J AJ; Zhao, Dekuang D; Wander, Seth A SA; Zhang, Yu Y; Natkunam, Yasodha Y; Slingerland, Joyce J; Reis, Isildinha M IM; Rabinovich, Brian B; Abdulreda, Midhat H MH; Moy, Vincent T VT; Lossos, Izidore S IS

Publication Date: 2021-12-14

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PubMed Link: 34543391

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An infection-induced RhoB-Beclin 1-Hsp90 complex enhances clearance of uropathogenic Escherichia coli.

Nature Communications

Miao, Chunhui C; Yu, Mingyu M; Pei, Geng G; Ma, Zhenyi Z; Zhang, Lisong L; Yang, Jianming J; Lv, Junqiang J; Zhang, Zhi-Song ZS; Keller, Evan T ET; Yao, Zhi Z; Wang, Quan Q

Publication Date: 2021-05-10

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PubMed Link: 33972537

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Small molecule modulation of the p75 neurotrophin receptor inhibits multiple amyloid beta-induced tau pathologies.

Scientific Reports

Yang, Tao T; Tran, Kevin C KC; Zeng, Anne Y AY; Massa, Stephen M SM; Longo, Frank M FM

Publication Date: 2020-11-23

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PubMed Link: 33230162

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• 41598_2020_Article_77210.pdf

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Molecular landscape and efficacy of HER2-targeted therapy in patients with HER2-mutated metastatic breast cancer.

Npj Breast Cancer

Yi, Zongbi Z; Rong, Guohua G; Guan, Yanfang Y; Li, Jin J; Chang, Lianpeng L; Li, Hui H; Liu, Binliang B; Wang, Wenna W; Guan, Xiuwen X; Ouyang, Quchang Q; Li, Lixi L; Zhai, Jingtong J; Li, Chunxiao C; Li, Lifeng L; Xia, Xuefeng X; Yang, Ling L; Qian, Haili H; Yi, Xin X; Xu, Binghe B; Ma, Fei F

Publication Date: 2020

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PubMed Link: 33145402

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TIMP1 preserves the blood-brain barrier through interacting with CD63/integrin 1 complex and regulating downstream FAK/RhoA signaling.

Acta Pharmaceutica Sinica. B

Tang, Jingshu J; Kang, Yuying Y; Huang, Longjian L; Wu, Lei L; Peng, Ying Y

Publication Date: 2020-06

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PubMed Link: 32642407

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RhoA-GTPase Modulates Neurite Outgrowth by Regulating the Expression of Spastin and p60-Katanin.

Cells

Tan, Dandan D; Zhang, Haowen H; Deng, Junyao J; Liu, Jingmin J; Wen, Jinkun J; Li, Lixia L; Wang, Xianghai X; Pan, Mengjie M; Hu, Xiaofang X; Guo, Jiasong J

Publication Date: 2020-01-16

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PubMed Link: 31963385

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• cells-09-00230.pdf

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Monitoring treatment efficacy and resistance in breast cancer patients via circulating tumor DNA genomic profiling.

Molecular Genetics & Genomic Medicine

Chen, Zhanhong Z; Sun, Tian T; Yang, Ziyan Z; Zheng, Yabing Y; Yu, Ruoying R; Wu, Xue X; Yan, Junrong J; Shao, Yang W YW; Shao, Xiying X; Cao, Wenming W; Wang, Xiaojia X

Publication Date: 2020-02

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PubMed Link: 31867841

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Arp2/3-Branched Actin Maintains an Active Pool of GTP-RhoA and Controls RhoA Abundance.

Cells

Huang, Yuxing Y; Yi, Xin X; Kang, Chenlu C; Wu, Congying C

Publication Date: 2019-10-16

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PubMed Link: 31623230

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• cells-08-01264.pdf

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Yes-associated protein (YAP) mediates adaptive cardiac hypertrophy in response to pressure overload.

The Journal Of Biological Chemistry

Byun, Jaemin J; Del Re, Dominic P DP; Zhai, Peiyong P; Ikeda, Shohei S; Shirakabe, Akihiro A; Mizushima, Wataru W; Miyamoto, Shigeki S; Brown, Joan H JH; Sadoshima, Junichi J

Publication Date: 2019-03-08

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PubMed Link: 30635403

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TM4SF5 promotes metastatic behavior of cells in 3D extracellular matrix gels by reducing dependency on environmental cues.

Oncotarget

Song, Dae-Geun DG; Lee, Gyu-Ho GH; Nam, Seo Hee SH; Cheong, Jin-Gyu JG; Jeong, Doyoung D; Lee, Seo-Jin SJ; Pan, Cheol-Ho CH; Jung, Jae Woo JW; Kim, Hye-Jin HJ; Ryu, Jihye J; Kim, Ji Eon JE; Kim, Somi S; Cho, Chang Yun CY; Kang, Min-Kyung MK; Lee, Kyung-Min KM; Lee, Jung Weon JW

Publication Date: 2017-10-13

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PubMed Link: 29137358

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• oncotarget-08-83480.pdf

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Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications

Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ

Publication Date: 2017-05-11

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PubMed Link: 28492226

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Fine tuning of Rac1 and RhoA alters cuspal shapes by remolding the cellular geometry.

Scientific Reports

Li, Liwen L; Tang, Qinghuang Q; Nakamura, Takashi T; Suh, Jun-Gyo JG; Ohshima, Hayato H; Jung, Han-Sung HS

Publication Date: 2016-11-28

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PubMed Link: 27892530

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• srep37828.pdf

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LOVTRAP: an optogenetic system for photoinduced protein dissociation.

Nature Methods

Wang, Hui H; Vilela, Marco M; Winkler, Andreas A; Tarnawski, Miroslaw M; Schlichting, Ilme I; Yumerefendi, Hayretin H; Kuhlman, Brian B; Liu, Rihe R; Danuser, Gaudenz G; Hahn, Klaus M KM

Publication Date: 2016-09

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PubMed Link: 27427858

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• nihms797900.pdf

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Metabolic/Proteomic Signature Defines Two Glioblastoma Subtypes With Different Clinical Outcome.

Scientific Reports

Marziali, G G; Signore, M M; Buccarelli, M M; Grande, S S; Palma, A A; Biffoni, M M; Rosi, A A; D'Alessandris, Q G QG; Martini, M M; Larocca, L M LM; De Maria, R R; Pallini, R R; Ricci-Vitiani, L L

Publication Date: 2016-02-09

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PubMed Link: 26857460

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• srep21557-s1.pdf

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Involvement of Membrane Blebbing in Immunological Disorders and Cancer.

Medical Principles And Practice : International Journal Of The Kuwait University, Health Science Centre

Khajah, Maitham A MA; Luqmani, Yunus A YA

Publication Date: 2016

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PubMed Link: 26488882

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Competition for actin between two distinct F-actin networks defines a bistable switch for cell polarization.

Nature Cell Biology

Lomakin, Alexis J AJ; Lee, Kun-Chun KC; Han, Sangyoon J SJ; Bui, Duyen A DA; Davidson, Michael M; Mogilner, Alex A; Danuser, Gaudenz G

Publication Date: 2015-11

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PubMed Link: 26414403

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The multi-targeted tyrosine kinase inhibitor vandetanib plays a bifunctional role in non-small cell lung cancer cells.

Scientific Reports

Zhou, Yan Y; Zhang, Yuanliang Y; Zou, Hanbing H; Cai, Ning N; Chen, Xiaojing X; Xu, Longmei L; Kong, Xianming X; Liu, Peifeng P

Publication Date: 2015-02-27

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PubMed Link: 25720956

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• srep08629.pdf

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In vivo imaging and characterization of actin microridges.

Plos One

Lam, Pui-ying PY; Mangos, Steve S; Green, Julie M JM; Reiser, Jochen J; Huttenlocher, Anna A

Publication Date: 2015

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PubMed Link: 25629723

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XB130-A Novel Adaptor Protein: Gene, Function, and Roles in Tumorigenesis.

Scientifica

Bai, Xiao-Hui XH; Cho, Hae-Ra HR; Moodley, Serisha S; Liu, Mingyao M

Publication Date: 2014

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PubMed Link: 24995146

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MCT-1 expression and PTEN deficiency synergistically promote neoplastic multinucleation through the Src/p190B signaling activation.

Oncogene

Wu, M-H MH; Chen, Y-A YA; Chen, H-H HH; Chang, K-W KW; Chang, I-S IS; Wang, L-H LH; Hsu, H-L HL

Publication Date: 2014-10-23

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PubMed Link: 24858043

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• onc2014125a.pdf

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3-Methylcholanthrene, an AhR agonist, caused cell-cycle arrest by histone deacetylation through a RhoA-dependent recruitment of HDAC1 and pRb2 to E2F1 complex.

Plos One

Chang, Chih-Cheng CC; Sue, Yuh-Mou YM; Yang, Nian-Jie NJ; Lee, Yi-Hsuan YH; Juan, Shu-Hui SH

Publication Date: 2014

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PubMed Link: 24658119

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ROCK inhibition activates MCF-7 cells.

Plos One

Yang, Seungwon S; Kim, Hyun-Man HM

Publication Date: 2014

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PubMed Link: 24523903

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Integrin-matrix clusters form podosome-like adhesions in the absence of traction forces.

Cell Reports

Yu, Cheng-han CH; Rafiq, Nisha Bte Mohd NB; Krishnasamy, Anitha A; Hartman, Kevin L KL; Jones, Gareth E GE; Bershadsky, Alexander D AD; Sheetz, Michael P MP

Publication Date: 2013-12-12

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PubMed Link: 24290759

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Stimulus-dependent phosphorylation of profilin-1 in angiogenesis.

Nature Cell Biology

Fan, Yi Y; Arif, Abul A; Gong, Yanqing Y; Jia, Jie J; Eswarappa, Sandeepa M SM; Willard, Belinda B; Horowitz, Arie A; Graham, Linda M LM; Penn, Marc S MS; Fox, Paul L PL

Publication Date: 2012-10

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PubMed Link: 23000962

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Distinct functional outputs of PTEN signalling are controlled by dynamic association with β-arrestins.

The Embo Journal

Lima-Fernandes, Evelyne E; Enslen, Hervé H; Camand, Emeline E; Kotelevets, Larissa L; Boularan, Cédric C; Achour, Lamia L; Benmerah, Alexandre A; Gibson, Lucien C D LC; Baillie, George S GS; Pitcher, Julie A JA; Chastre, Eric E; Etienne-Manneville, Sandrine S; Marullo, Stefano S; Scott, Mark G H MG

Publication Date: 2011-06-03

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PubMed Link: 21642958

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Gankyrin plays an essential role in Ras-induced tumorigenesis through regulation of the RhoA/ROCK pathway in mammalian cells.

The Journal Of Clinical Investigation

Man, Jiang-Hong JH; Liang, Bing B; Gu, Yue-Xi YX; Zhou, Tao T; Li, Ai-Ling AL; Li, Tao T; Jin, Bao-Feng BF; Bai, Bing B; Zhang, Hai-Ying HY; Zhang, Wei-Na WN; Li, Wei-Hua WH; Gong, Wei-Li WL; Li, Hui-Yan HY; Zhang, Xue-Min XM

Publication Date: 2010-08

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PubMed Link: 20628200

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Differential regulation of protrusion and polarity by PI3K during neutrophil motility in live zebrafish.

Developmental Cell

Yoo, Sa Kan SK; Deng, Qing Q; Cavnar, Peter J PJ; Wu, Yi I YI; Hahn, Klaus M KM; Huttenlocher, Anna A

Publication Date: 2010-02-16

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PubMed Link: 20159593

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Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival.

The Embo Journal

Drosten, Matthias M; Dhawahir, Alma A; Sum, Eleanor Y M EY; Urosevic, Jelena J; Lechuga, Carmen G CG; Esteban, Luis M LM; Castellano, Esther E; Guerra, Carmen C; Santos, Eugenio E; Barbacid, Mariano M

Publication Date: 2010-03-17

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PubMed Link: 20150892

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The Sex-determining region Y-box 4 and homeobox C6 transcriptional networks in prostate cancer progression: crosstalk with the Wnt, Notch, and PI3K pathways.

The American Journal Of Pathology

Moreno, Carlos S CS

Publication Date: 2010-02

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PubMed Link: 20019190

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Mechanistic analysis of the amplification and diversification events induced by Vav proteins in B-lymphocytes.

The Journal Of Biological Chemistry

Caloca, María J MJ; Zugaza, José L JL; Bustelo, Xosé R XR

Publication Date: 2008-12-26

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PubMed Link: 18974050

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Leptin induces phagocytosis of apoptotic bodies by hepatic stellate cells via a Rho guanosine triphosphatase-dependent mechanism.

Hepatology (Baltimore, Md.)

Jiang, Joy X JX; Mikami, Kenichiro K; Shah, Vijay H VH; Torok, Natalie J NJ

Publication Date: 2008-11

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PubMed Link: 18925608

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Nck adapters are involved in the formation of dorsal ruffles, cell migration, and Rho signaling downstream of the platelet-derived growth factor beta receptor.

The Journal Of Biological Chemistry

Ruusala, Aino A; Pawson, Tony T; Heldin, Carl-Henrik CH; Aspenström, Pontus P

Publication Date: 2008-10-31

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PubMed Link: 18765673

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