PIK3CA c.220_221delinsGA ;(p.T74D)

Variant ID: 3-178916833-AC-GA

NM_006218.2(PIK3CA):c.220_221delinsGA;(p.T74D)

This variant was identified in 7 publications

View GRCh38 version.




Publications:


Heterogeneity of the cancer cell line metabolic landscape.

Molecular Systems Biology
Shorthouse, David D; Bradley, Jenna J; Critchlow, Susan E SE; Bendtsen, Claus C; Hall, Benjamin A BA
Publication Date: 2022-11

Variant appearance in text: PIK3CA: T74D
PubMed Link: 36321551
Variant Present in the following documents:
  • MSB-18-e11006-s010.xlsx, sheet 1
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Fisetin induces DNA double-strand break and interferes with the repair of radiation-induced damage to radiosensitize triple negative breast cancer cells.

Journal Of Experimental & Clinical Cancer Research : Cr
Khozooei, Shayan S; Lettau, Konstanze K; Barletta, Francesca F; Jost, Tina T; Rebholz, Simone S; Veerappan, Soundaram S; Franz-Wachtel, Mirita M; Macek, Boris B; Iliakis, George G; Distel, Luitpold V LV; Zips, Daniel D; Toulany, Mahmoud M
Publication Date: 2022-08-22

Variant appearance in text: PI3K: T74D
PubMed Link: 35989353
Variant Present in the following documents:
  • 13046_2022_Article_2442.pdf
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Increased expression of glutamine transporter SNAT2/SLC38A2 promotes glutamine dependence and oxidative stress resistance, and is associated with worse prognosis in triple-negative breast cancer.

British Journal Of Cancer
Morotti, Matteo M; Zois, Christos E CE; El-Ansari, Rokaya R; Craze, Madeleine L ML; Rakha, Emad A EA; Fan, Shih-Jung SJ; Valli, Alessandro A; Haider, Syed S; Goberdhan, Deborah C I DCI; Green, Andrew R AR; Harris, Adrian L AL
Publication Date: 2021-01

Variant appearance in text: PIK3CA: T74D
PubMed Link: 33028955
Variant Present in the following documents:
  • 41416_2020_Article_1113.pdf
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Resveratrol as a Tumor-Suppressive Nutraceutical Modulating Tumor Microenvironment and Malignant Behaviors of Cancer.

International Journal Of Molecular Sciences
Han, Youngjin Y; Jo, HyunA H; Cho, Jae Hyun JH; Dhanasekaran, Danny N DN; Song, Yong Sang YS
Publication Date: 2019-02-20

Variant appearance in text: PI3K: T74D
PubMed Link: 30791624
Variant Present in the following documents:
  • Main text
  • ijms-20-00925.pdf
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Design of Hedgehog pathway inhibitors for cancer treatment.

Medicinal Research Reviews
Bariwal, Jitender J; Kumar, Virender V; Dong, Yuxiang Y; Mahato, Ram I RI
Publication Date: 2019-05

Variant appearance in text: PI3K: T74D
PubMed Link: 30484872
Variant Present in the following documents:
  • Main text
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Tracing anti-cancer and cancer-promoting actions of all-trans retinoic acid in breast cancer to a RARĪ± epigenetic mechanism of mammary epithelial cell fate.

Oncotarget
Rossetti, Stefano S; Ren, MingQiang M; Visconti, Nicolo N; Corlazzoli, Francesca F; Gagliostro, Vincenzo V; Somenzi, Giulia G; Yao, Jin J; Sun, Yijun Y; Sacchi, Nicoletta N
Publication Date: 2016-12-27

Variant appearance in text: PI3K: T74D
PubMed Link: 27894085
Variant Present in the following documents:
  • Main text
  • oncotarget-07-87064.pdf
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The aromatase inhibitor letrozole and inhibitors of insulin-like growth factor I receptor synergistically induce apoptosis in in vitro models of estrogen-dependent breast cancer.

Breast Cancer Research : Bcr
Lisztwan, Joanna J; Pornon, Astrid A; Chen, Bin B; Chen, Shiuan S; Evans, Dean B DB
Publication Date: 2008

Variant appearance in text: PI3K: T74D
PubMed Link: 18611244
Variant Present in the following documents:
  • Main text
  • bcr2113.pdf
View BVdb publication page