PIK3CA c.224A>T ;(p.Q75L)

Variant ID: 3-178916837-A-T

NM_006218.2(PIK3CA):c.224A>T;(p.Q75L)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


Targeting Glucose Metabolism Sensitizes Pancreatic Cancer to MEK Inhibition.

Cancer Research
Yan, Liang L; Tu, Bo B; Yao, Jun J; Gong, Jing J; Carugo, Alessandro A; Bristow, Christopher A CA; Wang, Qiuyun Q; Zhu, Cihui C; Dai, Bingbing B; Kang, Ya'an Y; Han, Leng L; Feng, Ningping N; Jin, Yanqing Y; Fleming, Jason J; Heffernan, Timothy P TP; Yao, Wantong W; Ying, Haoqiang H
Publication Date: 2021-08-01

Variant appearance in text: PI3K: Q75L
PubMed Link: 34117030
Variant Present in the following documents:
  • Main text
View BVdb publication page



Developmental fidelity is imposed by genetically separable RalGEF activities that mediate opposing signals.

Plos Genetics
Shin, Hanna H; Braendle, Christian C; Monahan, Kimberly B KB; Kaplan, Rebecca E W REW; Zand, Tanya P TP; Mote, Francisca Sefakor FS; Peters, Eldon C EC; Reiner, David J DJ
Publication Date: 2019-05

Variant appearance in text: PI3K: Q75L
PubMed Link: 31086367
Variant Present in the following documents:
  • Main text
View BVdb publication page



KRAS-dependent suppression of MYC enhances the sensitivity of cancer cells to cytotoxic agents.

Oncotarget
Ischenko, Irene I; Zhi, Jizu J; Hayman, Michael J MJ; Petrenko, Oleksi O
Publication Date: 2017-03-14

Variant appearance in text: PIK3CA: Q75L
PubMed Link: 28152508
Variant Present in the following documents:
  • Main text
  • oncotarget-08-17995.pdf
View BVdb publication page



NF1 is a tumor suppressor in neuroblastoma that determines retinoic acid response and disease outcome.

Cell
Hölzel, Michael M; Huang, Sidong S; Koster, Jan J; Ora, Ingrid I; Lakeman, Arjan A; Caron, Huib H; Nijkamp, Wouter W; Xie, Jing J; Callens, Tom T; Asgharzadeh, Shahab S; Seeger, Robert C RC; Messiaen, Ludwine L; Versteeg, Rogier R; Bernards, René R
Publication Date: 2010-07-23

Variant appearance in text: PIK3CA: Q75L
PubMed Link: 20655465
Variant Present in the following documents:
  • Main text
View BVdb publication page