Publications:

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Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.

Nature Communications

Havugimana, Pierre C PC; Goel, Raghuveera Kumar RK; Phanse, Sadhna S; Youssef, Ahmed A; Padhorny, Dzmitry D; Kotelnikov, Sergei S; Kozakov, Dima D; Emili, Andrew A

Publication Date: 2022-07-13

Variant appearance in text: PIK3CA: E76K

PubMed Link: 35831314

Variant Present in the following documents:

• 41467_2022_31809_MOESM8_ESM.xlsx, sheet 3

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Utility of plasma cell-free DNA for de novo detection and quantification of clonal hematopoiesis.

Haematologica

Gutierrez-Rodrigues, Fernanda F; Beerman, Isabel I; Groarke, Emma M EM; Patel, Bhavisha A BA; Spitofsky, Nina N; Dillon, Laura W LW; Raffo, Diego Quinones DQ; Hourigan, Christopher S CS; Kajigaya, Sachiko S; Ferrucci, Luigi L; Young, Neal S NS

Publication Date: 2022-08-01

Variant appearance in text: PIK3CA: 226G>A; Glu76Lys

PubMed Link: 34587721

Variant Present in the following documents:

• 2021_279230_GUTIERREZ-RODRIGUES_SUPPL.pdf

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Non-hotspot PIK3CA mutations are more frequent in CLOVES than in common or combined lymphatic malformations.

Orphanet Journal Of Rare Diseases

Brouillard, Pascal P; Schlögel, Matthieu J MJ; Homayun Sepehr, Nassim N; Helaers, Raphaël R; Queisser, Angela A; Fastré, Elodie E; Boutry, Simon S; Schmitz, Sandra S; Clapuyt, Philippe P; Hammer, Frank F; Dompmartin, Anne A; Weitz-Tuoretmaa, Annamaria A; Laranne, Jussi J; Pasquesoone, Louise L; Vilain, Catheline C; Boon, Laurence M LM; Vikkula, Miikka M

Publication Date: 2021-06-10

Variant appearance in text: PIK3CA: E76K

PubMed Link: 34112235

Variant Present in the following documents:

• Main text
• 13023_2021_Article_1898.pdf

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The dark side of histones: genomic organization and role of oncohistones in cancer.

Clinical Epigenetics

Amatori, Stefano S; Tavolaro, Simona S; Gambardella, Stefano S; Fanelli, Mirco M

Publication Date: 2021-04-07

Variant appearance in text: PIK3CA: E76K

PubMed Link: 33827674

Variant Present in the following documents:

• Main text

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Short H2A histone variants are expressed in cancer.

Nature Communications

Chew, Guo-Liang GL; Bleakley, Marie M; Bradley, Robert K RK; Malik, Harmit S HS; Henikoff, Steven S; Molaro, Antoine A; Sarthy, Jay J

Publication Date: 2021-01-20

Variant appearance in text: PI3K: E76K

PubMed Link: 33473122

Variant Present in the following documents:

• Main text
• 41467_2020_Article_20707.pdf

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A Mutation in Histone H2B Represents a New Class of Oncogenic Driver.

Cancer Discovery

Bennett, Richard L RL; Bele, Aditya A; Small, Eliza C EC; Will, Christine M CM; Nabet, Behnam B; Oyer, Jon A JA; Huang, Xiaoxiao X; Ghosh, Rajarshi P RP; Grzybowski, Adrian T AT; Yu, Tao T; Zhang, Qiao Q; Riva, Alberto A; Lele, Tanmay P TP; Schatz, George C GC; Kelleher, Neil L NL; Ruthenburg, Alexander J AJ; Liphardt, Jan J; Licht, Jonathan D JD

Publication Date: 2019-10

Variant appearance in text: PIK3CA: E76K

PubMed Link: 31337617

Variant Present in the following documents:

• Main text

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Pharmacologic inhibition of PI3K p110δ in mutant Shp2E76K-expressing mice.

Oncotarget

Deng, Lisa L; Virts, Elizabeth L EL; Kapur, Reuben R; Chan, Rebecca J RJ

Publication Date: 2017-10-17

Variant appearance in text: PI3K: E76K

PubMed Link: 29156682

Variant Present in the following documents:

• Main text
• oncotarget-08-84776.pdf

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Clinical significance of frequent somatic mutations detected by high-throughput targeted sequencing in archived colorectal cancer samples.

Journal Of Translational Medicine

Dallol, Ashraf A; Buhmeida, Abdelbaset A; Al-Ahwal, Mahmoud Shaheen MS; Al-Maghrabi, Jaudah J; Bajouh, Osama O; Al-Khayyat, Shadi S; Alam, Rania R; Abusanad, Atlal A; Turki, Rola R; Elaimi, Aisha A; Alhadrami, Hani A HA; Abuzenadah, Mohammed M; Banni, Huda H; Al-Qahtani, Mohammed H MH; Abuzenadah, Adel M AM

Publication Date: 2016-05-04

Variant appearance in text: PIK3CA: Glu76Lys

PubMed Link: 27146902

Variant Present in the following documents:

• Main text

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Functions of Shp2 in cancer.

Journal Of Cellular And Molecular Medicine

Zhang, Jie J; Zhang, Fei F; Niu, Ruifang R

Publication Date: 2015-09

Variant appearance in text: PI3K: E76K

PubMed Link: 26088100

Variant Present in the following documents:

• Main text
• jcmm0019-2075.pdf

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New approaches to prevent LEOPARD syndrome-associated cardiac hypertrophy by specifically targeting Shp2-dependent signaling.

The Journal Of Biological Chemistry

Schramm, Christine C; Edwards, Michelle A MA; Krenz, Maike M

Publication Date: 2013-06-21

Variant appearance in text: PI3K: E76K

PubMed Link: 23673659

Variant Present in the following documents:

• Main text

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Genetic disruption of the PI3K regulatory subunits, p85α, p55α, and p50α, normalizes mutant PTPN11-induced hypersensitivity to GM-CSF.

Haematologica

Goodwin, Charles B CB; Yang, Zhenyun Z; Yin, Fuqin F; Yu, Menggang M; Chan, Rebecca J RJ

Publication Date: 2012-07

Variant appearance in text: PI3K: E76K

PubMed Link: 22315502

Variant Present in the following documents:

• Main text

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