PIK3CA c.614A>T ;(p.Q205L)

Variant ID: 3-178919129-A-T

NM_006218.2(PIK3CA):c.614A>T;(p.Q205L)

This variant was identified in 10 publications

View GRCh38 version.




Publications:


DEVOLUTION-A method for phylogenetic reconstruction of aneuploid cancers based on multiregional genotyping data.

Communications Biology
Andersson, Natalie N; Chattopadhyay, Subhayan S; Valind, Anders A; Karlsson, Jenny J; Gisselsson, David D
Publication Date: 2021-09-20

Variant appearance in text: PIK3CA: Q205L
PubMed Link: 34545199
Variant Present in the following documents:
  • 42003_2021_2637_MOESM2_ESM.pdf
View BVdb publication page



Activation of G-Protein Coupled Receptor-Gαi Signaling Increases Keratinocyte Proliferation and Reduces Differentiation, Leading to Epidermal Hyperplasia.

The Journal Of Investigative Dermatology
Pedro, M Pilar MP; Salinas Parra, Natalia N; Gutkind, J Silvio JS; Iglesias-Bartolome, Ramiro R
Publication Date: 2020-06

Variant appearance in text: PI3K: Q205L
PubMed Link: 31707029
Variant Present in the following documents:
  • Main text
View BVdb publication page



Gβγ signaling to the chemotactic effector P-REX1 and mammalian cell migration is directly regulated by Gαq and Gα13 proteins.

The Journal Of Biological Chemistry
Cervantes-Villagrana, Rodolfo Daniel RD; Adame-García, Sendi Rafael SR; García-Jiménez, Irving I; Color-Aparicio, Víctor Manuel VM; Beltrán-Navarro, Yarely Mabell YM; König, Gabriele M GM; Kostenis, Evi E; Reyes-Cruz, Guadalupe G; Gutkind, J Silvio JS; Vázquez-Prado, José J
Publication Date: 2019-01-11

Variant appearance in text: PI3K: Q205L
PubMed Link: 30446620
Variant Present in the following documents:
  • Main text
View BVdb publication page



Pharmacological targeting of CXCL12/CXCR4 signaling in prostate cancer bone metastasis.

Molecular Cancer
Conley-LaComb, M Katie MK; Semaan, Louie L; Singareddy, Rajareddy R; Li, Yanfeng Y; Heath, Elisabeth I EI; Kim, Seongho S; Cher, Michael L ML; Chinni, Sreenivasa R SR
Publication Date: 2016-11-03

Variant appearance in text: PI3K: Q205L
PubMed Link: 27809841
Variant Present in the following documents:
  • 12943_2016_Article_552.pdf
View BVdb publication page



Activation of G proteins by GIV-GEF is a pivot point for insulin resistance and sensitivity.

Molecular Biology Of The Cell
Ma, Gary S GS; Lopez-Sanchez, Inmaculada I; Aznar, Nicolas N; Kalogriopoulos, Nicholas N; Pedram, Shabnam S; Midde, Krishna K; Ciaraldi, Theodore P TP; Henry, Robert R RR; Ghosh, Pradipta P
Publication Date: 2015-11-15

Variant appearance in text: PI3K: Q205L
PubMed Link: 26378251
Variant Present in the following documents:
  • 4209.pdf
View BVdb publication page



Regulation of the epithelial Na+ channel by the RH domain of G protein-coupled receptor kinase, GRK2, and Galphaq/11.

The Journal Of Biological Chemistry
Lee, Il-Ha IH; Song, Sung-Hee SH; Campbell, Craig R CR; Kumar, Sharad S; Cook, David I DI; Dinudom, Anuwat A
Publication Date: 2011-06-03

Variant appearance in text: PI3K: Q205L
PubMed Link: 21464134
Variant Present in the following documents:
  • Main text
View BVdb publication page



A novel pathway for receptor-mediated post-translational activation of inducible nitric oxide synthase.

Journal Of Cellular And Molecular Medicine
Brovkovych, Viktor V; Zhang, Yongkang Y; Brovkovych, Svitlana S; Minshall, Richard D RD; Skidgel, Randal A RA
Publication Date: 2011-02

Variant appearance in text: PI3K: Q205L
PubMed Link: 20015194
Variant Present in the following documents:
  • Main text
  • jcmm0015-0258.pdf
View BVdb publication page



Multiple signalling pathways involved in beta2-adrenoceptor-mediated glucose uptake in rat skeletal muscle cells.

British Journal Of Pharmacology
Nevzorova, Julia J; Evans, Bronwyn A BA; Bengtsson, Tore T; Summers, Roger J RJ
Publication Date: 2006-02

Variant appearance in text: PI3K: Q205L
PubMed Link: 16415914
Variant Present in the following documents:
  • Main text
View BVdb publication page



Activation of B-Raf and regulation of the mitogen-activated protein kinase pathway by the G(o) alpha chain.

Molecular Biology Of The Cell
Antonelli, V V; Bernasconi, F F; Wong, Y H YH; Vallar, L L
Publication Date: 2000-04

Variant appearance in text: PI3K: Q205L
PubMed Link: 10749919
Variant Present in the following documents:
  • Main text
View BVdb publication page