PIK3CA c.1028A>G ;(p.Y343C)

Variant ID: 3-178921546-A-G

NM_006218.2(PIK3CA):c.1028A>G;(p.Y343C)

This variant was identified in 10 publications

View GRCh38 version.




Publications:


Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.

Nature Communications
Havugimana, Pierre C PC; Goel, Raghuveera Kumar RK; Phanse, Sadhna S; Youssef, Ahmed A; Padhorny, Dzmitry D; Kotelnikov, Sergei S; Kozakov, Dima D; Emili, Andrew A
Publication Date: 2022-07-13

Variant appearance in text: PIK3CA: 1028A>G; Tyr343Cys
PubMed Link: 35831314
Variant Present in the following documents:
  • 41467_2022_31809_MOESM8_ESM.xlsx, sheet 3
View BVdb publication page



Improved Treatment Outcomes by Using Patient Specific Drug Combinations in Mammalian Target of Rapamycin Activated Advanced Metastatic Cancers.

Frontiers In Pharmacology
Crook, Timothy T; Patil, Darshana D; Gaya, Andrew A; Plowman, Nicholas N; Limaye, Sewanti S; Ranade, Anantbhushan A; Bhatt, Amit A; Page, Raymond R; Akolkar, Dadasaheb D
Publication Date: 2021

Variant appearance in text: PIK3CA: Y343C
PubMed Link: 33935721
Variant Present in the following documents:
  • Main text
View BVdb publication page



Circulating tumour DNA in metastatic breast cancer to guide clinical trial enrolment and precision oncology: A cohort study.

Plos Medicine
Zivanovic Bujak, Andjelija A; Weng, Chen-Fang CF; Silva, Maria João MJ; Yeung, Miriam M; Lo, Louisa L; Ftouni, Sarah S; Litchfield, Cassandra C; Ko, Yi-An YA; Kuykhoven, Keilly K; Van Geelen, Courtney C; Chandrashekar, Sushma S; Dawson, Mark A MA; Loi, Sherene S; Wong, Stephen Q SQ; Dawson, Sarah-Jane SJ
Publication Date: 2020-10

Variant appearance in text: PIK3CA: Y343C
PubMed Link: 33001984
Variant Present in the following documents:
  • pmed.1003363.s013.xlsx, sheet 1
View BVdb publication page



Reproducible Analysis of Post-Translational Modifications in Proteomes--Application to Human Mutations.

Plos One
Holehouse, Alex S AS; Naegle, Kristen M KM
Publication Date: 2015

Variant appearance in text: PI3K: Y343C
PubMed Link: 26659599
Variant Present in the following documents:
  • pone.0144692.s002.xlsx, sheet 1
View BVdb publication page



GESPA: classifying nsSNPs to predict disease association.

Bmc Bioinformatics
Khurana, Jay K JK; Reeder, Jay E JE; Shrimpton, Antony E AE; Thakar, Juilee J
Publication Date: 2015-07-25

Variant appearance in text: PIK3CA: Y343C
PubMed Link: 26206375
Variant Present in the following documents:
  • 12859_2015_673_MOESM1_ESM.xls, sheet 2
View BVdb publication page



The determinants of head and neck cancer: Unmasking the PI3K pathway mutations.

Journal Of Carcinogenesis & Mutagenesis
Giudice, Fernanda S FS; Squarize, Cristiane H CH
Publication Date: 2013-08-02

Variant appearance in text: PI3K: Y343C
PubMed Link: 25126449
Variant Present in the following documents:
  • Main text
View BVdb publication page



Predicting the functional impact of protein mutations: application to cancer genomics.

Nucleic Acids Research
Reva, Boris B; Antipin, Yevgeniy Y; Sander, Chris C
Publication Date: 2011-09-01

Variant appearance in text: PIK3CA: Y343C
PubMed Link: 21727090
Variant Present in the following documents:
  • supp_gkr407_Supplement2_Table_SM1_COSMIC_mutations.xls, sheet 1
View BVdb publication page



EGFR-PI3K-AKT-mTOR signaling in head and neck squamous cell carcinomas: attractive targets for molecular-oriented therapy.

Expert Opinion On Therapeutic Targets
Freudlsperger, Christian C; Burnett, Jeffrey R JR; Friedman, Jay A JA; Kannabiran, Vishnu R VR; Chen, Zhong Z; Van Waes, Carter C
Publication Date: 2011-01

Variant appearance in text: PIK3CA: Y343C
PubMed Link: 21110697
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genome-wide analysis to predict protein sequence variations that change phosphorylation sites or their corresponding kinases.

Nucleic Acids Research
Ryu, Gil-Mi GM; Song, Pamela P; Kim, Kyu-Won KW; Oh, Kyung-Soo KS; Park, Keun-Joon KJ; Kim, Jong Hun JH
Publication Date: 2009-03

Variant appearance in text: PIK3CA: Y343C
PubMed Link: 19139070
Variant Present in the following documents:
  • gkn1008_nar-01723-s-2008-File009.xls, sheet 1
View BVdb publication page



PIK3CA mutations in head and neck squamous cell carcinoma.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Qiu, Wanglong W; Schönleben, Frank F; Li, Xiaojun X; Ho, Daniel J DJ; Close, Lanny G LG; Manolidis, Spiros S; Bennett, Boyce P BP; Su, Gloria H GH
Publication Date: 2006-03-01

Variant appearance in text: PIK3CA: Y343C
PubMed Link: 16533766
Variant Present in the following documents:
  • Main text
View BVdb publication page