Biology and targetability of the extended spectrum of PIK3CA mutations (PIK3CAm) detected in breast carcinoma.
Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Rugo, Hope S HS; Raskina, Kira K; Schrock, Alexa B AB; Madison, Russell W RW; Graf, Ryon P RP; Sokol, Ethan S ES; Sivakumar, Smruthy S SS; Lee, Jessica K JK; Fisher, Virginia V; Oxnard, Geoffrey R GR; Tukachinsky, Hanna H
EGFR-RAD51 gene fusion NSCLC responsiveness to different generation EGFR-TKIs: two cases and review of the literature.
Translational Lung Cancer Research
Di Federico, Alessandro A; Filetti, Marco M; Palladini, Arianna A; Giusti, Raffaele R; Piras, Marta M; De Giglio, Andrea A; Ardizzoni, Andrea A; Gelsomino, Francesco F
Biomarkers in Breast Cancer: An Integrated Analysis of Comprehensive Genomic Profiling and PD-L1 Immunohistochemistry Biomarkers in 312 Patients with Breast Cancer.
The Oncologist
Huang, Richard S P RSP; Li, Xinyan X; Haberberger, James J; Sokol, Ethan E; Severson, Eric E; Duncan, Daniel L DL; Hemmerich, Amanda A; Edgerly, Claire C; Williams, Erik E; Elvin, Julia J; Vergilio, Jo-Anne JA; Killian, Jonathan Keith JK; Lin, Douglas D; Hiemenz, Matthew M; Xiao, Jinpeng J; McEwan, Deborah D; Holmes, Oliver O; Danziger, Natalie N; Erlich, Rachel R; Frampton, Garrett G; Cohen, Michael B MB; McGregor, Kimberly K; Reddy, Prasanth P; Cardeiro, Dawn D; Anhorn, Rachel R; Venstrom, Jeffrey J; Alexander, Brian B; Brown, Charlotte C; Pusztai, Lajos L; Ross, Jeffrey S JS; Ramkissoon, Shakti H SH
Phase and context shape the function of composite oncogenic mutations.
Nature
Gorelick, Alexander N AN; Sánchez-Rivera, Francisco J FJ; Cai, Yanyan Y; Bielski, Craig M CM; Biederstedt, Evan E; Jonsson, Philip P; Richards, Allison L AL; Vasan, Neil N; Penson, Alexander V AV; Friedman, Noah D ND; Ho, Yu-Jui YJ; Baslan, Timour T; Bandlamudi, Chaitanya C; Scaltriti, Maurizio M; Schultz, Nikolaus N; Lowe, Scott W SW; Reznik, Ed E; Taylor, Barry S BS
PIK3CA C2 Domain Deletions Hyperactivate Phosphoinositide 3-kinase (PI3K), Generate Oncogene Dependence, and Are Exquisitely Sensitive to PI3Kα Inhibitors.
Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Croessmann, Sarah S; Sheehan, Jonathan H JH; Lee, Kyung-Min KM; Sliwoski, Gregory G; He, Jie J; Nagy, Rebecca R; Riddle, David D; Mayer, Ingrid A IA; Balko, Justin M JM; Lanman, Richard R; Miller, Vincent A VA; Cantley, Lewis C LC; Meiler, Jens J; Arteaga, Carlos L CL