PIK3CA c.1490A>G ;(p.N497S)

Variant ID: 3-178928304-A-G

NM_006218.2(PIK3CA):c.1490A>G;(p.N497S)

This variant was identified in 9 publications

View GRCh38 version.




Publications:


The Discrepancy Between Standard Histologic WHO Grading of Meningioma and Molecular Profile: A Single Institution Series.

Frontiers In Oncology
Roehrkasse, Amanda M AM; Peterson, Jo Elle G JEG; Fung, Kar-Ming KM; Pelargos, Panayiotis E PE; Dunn, Ian F IF
Publication Date: 2022

Variant appearance in text: PIK3CA: N497S
PubMed Link: 35299730
Variant Present in the following documents:
  • DataSheet_1.pdf
View BVdb publication page



A genetically defined signature of responsiveness to erlotinib in early-stage pancreatic cancer patients: Results from the CONKO-005 trial.

Ebiomedicine
Hoyer, K K; Hablesreiter, R R; Inoue, Y Y; Yoshida, K K; Briest, F F; Christen, F F; Kakiuchi, N N; Yoshizato, T T; Shiozawa, Y Y; Shiraishi, Y Y; Striefler, J K JK; Bischoff, S S; Lohneis, P P; Putter, H H; Blau, O O; Keilholz, U U; Bullinger, L L; Pelzer, U U; Hummel, M M; Riess, H H; Ogawa, S S; Sinn, M M; Damm, F F
Publication Date: 2021-04

Variant appearance in text: PIK3CA: N497S
PubMed Link: 33862582
Variant Present in the following documents:
  • mmc3.xlsx, sheet 2
View BVdb publication page



Influence of TP53 Mutation on Survival in Patients With Advanced EGFR-Mutant Non-Small-Cell Lung Cancer.

Jco Precision Oncology
Aggarwal, Charu C; Davis, Christiana W CW; Mick, Rosemarie R; Thompson, Jeffrey C JC; Ahmed, Saman S; Jeffries, Seth S; Bagley, Stephen S; Gabriel, Peter P; Evans, Tracey L TL; Bauml, Joshua M JM; Ciunci, Christine C; Alley, Evan E; Morrissette, Jennifer J D JJD; Cohen, Roger B RB; Carpenter, Erica L EL; Langer, Corey J CJ
Publication Date: 2018

Variant appearance in text: PIK3CA: N497S
PubMed Link: 30766968
Variant Present in the following documents:
  • Main text
View BVdb publication page



Germline mutations in candidate predisposition genes in individuals with cutaneous melanoma and at least two independent additional primary cancers.

Plos One
Pritchard, Antonia L AL; Johansson, Peter A PA; Nathan, Vaishnavi V; Howlie, Madeleine M; Symmons, Judith J; Palmer, Jane M JM; Hayward, Nicholas K NK
Publication Date: 2018

Variant appearance in text: PIK3CA: 1490A>G; Asn497Ser; rs753879573
PubMed Link: 29641532
Variant Present in the following documents:
  • pone.0194098.s003.xlsx, sheet 10
View BVdb publication page



Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients.

Nature Communications
Chen, Li L; Yang, Liu L; Yao, Ling L; Kuang, Xia-Ying XY; Zuo, Wen-Jia WJ; Li, Shan S; Qiao, Feng F; Liu, Yi-Rong YR; Cao, Zhi-Gang ZG; Zhou, Shu-Ling SL; Zhou, Xiao-Yan XY; Yang, Wen-Tao WT; Shi, Jin-Xiu JX; Huang, Wei W; Hu, Xin X; Shao, Zhi-Ming ZM
Publication Date: 2018-04-10

Variant appearance in text: PIK3CA: N497S
PubMed Link: 29636477
Variant Present in the following documents:
  • 41467_2018_3867_MOESM1_ESM.pdf
  • 41467_2018_Article_3867.pdf
View BVdb publication page



Insulin resistance uncoupled from dyslipidemia due to C-terminal PIK3R1 mutations.

Jci Insight
Huang-Doran, Isabel I; Tomlinson, Patsy P; Payne, Felicity F; Gast, Alexandra A; Sleigh, Alison A; Bottomley, William W; Harris, Julie J; Daly, Allan A; Rocha, Nuno N; Rudge, Simon S; Clark, Jonathan J; Kwok, Albert A; Romeo, Stefano S; McCann, Emma E; Müksch, Barbara B; Dattani, Mehul M; Zucchini, Stefano S; Wakelam, Michael M; Foukas, Lazaros C LC; Savage, David B DB; Murphy, Rinki R; O'Rahilly, Stephen S; Barroso, Inês I; Semple, Robert K RK
Publication Date: 2016-10-20

Variant appearance in text: PI3K: N497S
PubMed Link: 27766312
Variant Present in the following documents:
  • jciinsight-1-88766-s001.pdf
View BVdb publication page



The molecular landscape of extraskeletal osteosarcoma: A clinicopathological and molecular biomarker study.

The Journal Of Pathology. Clinical Research
Jour, George G; Wang, Lu L; Middha, Sumit S; Zehir, Ahmet A; Chen, Wen W; Sadowska, Justyna J; Healey, John J; Agaram, Narasimhan P NP; Choi, Lisa L; Nafa, Khedoudja K; Hameed, Meera M
Publication Date: 2016-01

Variant appearance in text: PIK3CA: 1490A>G; N497S
PubMed Link: 27499911
Variant Present in the following documents:
  • CJP2-2-09-s001.xlsx, sheet 1
View BVdb publication page



Uncovering the genomic heterogeneity of multifocal breast cancer.

The Journal Of Pathology
Desmedt, Christine C; Fumagalli, Debora D; Pietri, Elisabetta E; Zoppoli, Gabriele G; Brown, David D; Nik-Zainal, Serena S; Gundem, Gunes G; Rothé, Françoise F; Majjaj, Samira S; Garuti, Anna A; Carminati, Enrico E; Loi, Sherene S; Van Brussel, Thomas T; Boeckx, Bram B; Maetens, Marion M; Mudie, Laura L; Vincent, Delphine D; Kheddoumi, Naima N; Serra, Luigi L; Massa, Ilaria I; Ballestrero, Alberto A; Amadori, Dino D; Salgado, Roberto R; de Wind, Alexandre A; Lambrechts, Diether D; Piccart, Martine M; Larsimont, Denis D; Campbell, Peter J PJ; Sotiriou, Christos C
Publication Date: 2015-08

Variant appearance in text: PIK3CA: 1490A>G; N497S
PubMed Link: 25850943
Variant Present in the following documents:
  • path0236-0457-sd9.xlsx, sheet 1
View BVdb publication page



PIK3CA mutation impact on survival in breast cancer patients and in ERα, PR and ERBB2-based subgroups.

Breast Cancer Research : Bcr
Cizkova, Magdalena M; Susini, Aurélie A; Vacher, Sophie S; Cizeron-Clairac, Géraldine G; Andrieu, Catherine C; Driouch, Keltouma K; Fourme, Emmanuelle E; Lidereau, Rosette R; Bièche, Ivan I
Publication Date: 2012-02-13

Variant appearance in text: PIK3CA: 1490A>G
PubMed Link: 22330809
Variant Present in the following documents:
  • Main text
  • bcr3113.pdf
View BVdb publication page