Publications:

S6K1-mediated phosphorylation of PDK1 impairs AKT kinase activity and oncogenic functions.

Nature Communications

Jiang, Qiwei Q; Zhang, Xiaomei X; Dai, Xiaoming X; Han, Shiyao S; Wu, Xueji X; Wang, Lei L; Wei, Wenyi W; Zhang, Ning N; Xie, Wei W; Guo, Jianping J

Publication Date: 2022-03-22

Variant appearance in text: PI3K: S501A

PubMed Link: 35318320

Variant Present in the following documents:

• 41467_2022_28910_MOESM1_ESM.pdf

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Monoallelic loss of the imprinted gene Grb10 promotes tumor formation in irradiated Nf1+/- mice.

Plos Genetics

Mroue, Rana R; Huang, Brian B; Braunstein, Steve S; Firestone, Ari J AJ; Nakamura, Jean L JL

Publication Date: 2015-05

Variant appearance in text: PI3K: S501A

PubMed Link: 26000738

Variant Present in the following documents:

• Main text

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Bora downregulation results in radioresistance by promoting repair of double strand breaks.

Plos One

Cairns, Junmei J; Peng, Yi Y; Yee, Vivien C VC; Lou, Zhenkun Z; Wang, Liewei L

Publication Date: 2015

Variant appearance in text: PI3K: S501A

PubMed Link: 25742493

Variant Present in the following documents:

• Main text
• pone.0119208.pdf

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Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling.

Science (New York, N.Y.)

Yu, Yonghao Y; Yoon, Sang-Oh SO; Poulogiannis, George G; Yang, Qian Q; Ma, Xiaoju Max XM; Villén, Judit J; Kubica, Neil N; Hoffman, Gregory R GR; Cantley, Lewis C LC; Gygi, Steven P SP; Blenis, John J

Publication Date: 2011-06-10

Variant appearance in text: PI3K: S501A

PubMed Link: 21659605

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NGF rapidly increases membrane expression of TRPV1 heat-gated ion channels.

The Embo Journal

Zhang, Xuming X; Huang, Jiehong J; McNaughton, Peter A PA

Publication Date: 2005-12-21

Variant appearance in text: PI3K: S501A

PubMed Link: 16319926

Variant Present in the following documents:

• Main text

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