PIK3CA c.1523A>T ;(p.Y508F)

Variant ID: 3-178928337-A-T

NM_006218.2(PIK3CA):c.1523A>T;(p.Y508F)

This variant was identified in 10 publications

View GRCh38 version.




Publications:


Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.

Nature Communications
Havugimana, Pierre C PC; Goel, Raghuveera Kumar RK; Phanse, Sadhna S; Youssef, Ahmed A; Padhorny, Dzmitry D; Kotelnikov, Sergei S; Kozakov, Dima D; Emili, Andrew A
Publication Date: 2022-07-13

Variant appearance in text: PIK3CA: 1523A>T; Y508F
PubMed Link: 35831314
Variant Present in the following documents:
  • 41467_2022_31809_MOESM8_ESM.xlsx, sheet 3
View BVdb publication page



Short tandem repeat profiling for the authentication of cancer stem-like cells.

International Journal Of Cancer
Visconti, Paola P; Parodi, Federica F; Parodi, Barbara B; Casarino, Lucia L; Romano, Paolo P; Buccarelli, Mariachiara M; Pallini, Roberto R; D'Alessandris, Quintino Giorgio QG; Montori, Andrea A; Pilozzi, Emanuela E; Ricci-Vitiani, Lucia L
Publication Date: 2021-03-15

Variant appearance in text: PIK3CA: 1523A>T; Tyr508Phe
PubMed Link: 33128777
Variant Present in the following documents:
  • IJC-148-1489-s001.pdf
View BVdb publication page



Lyn, Lupus, and (B) Lymphocytes, a Lesson on the Critical Balance of Kinase Signaling in Immunity.

Frontiers In Immunology
Brodie, Erica J EJ; Infantino, Simona S; Low, Michael S Y MSY; Tarlinton, David M DM
Publication Date: 2018

Variant appearance in text: PI3K: Y508F
PubMed Link: 29545808
Variant Present in the following documents:
  • Main text
View BVdb publication page



Axitinib and sorafenib are potent in tyrosine kinase inhibitor resistant chronic myeloid leukemia cells.

Cell Communication And Signaling : Ccs
Halbach, Sebastian S; Hu, Zehan Z; Gretzmeier, Christine C; Ellermann, Julia J; Wöhrle, Franziska U FU; Dengjel, Jörn J; Brummer, Tilman T
Publication Date: 2016-02-24

Variant appearance in text: PI3K: Y508F
PubMed Link: 26912052
Variant Present in the following documents:
  • Main text
  • 12964_2016_129_MOESM8_ESM.pdf
  • 12964_2016_Article_129.pdf
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Lyn facilitates glioblastoma cell survival under conditions of nutrient deprivation by promoting autophagy.

Plos One
Liu, Wei Michael WM; Huang, Ping P; Kar, Niladri N; Burgett, Monica M; Muller-Greven, Gaelle G; Nowacki, Amy S AS; Distelhorst, Clark W CW; Lathia, Justin D JD; Rich, Jeremy N JN; Kappes, John C JC; Gladson, Candece L CL
Publication Date: 2013

Variant appearance in text: PI3K: Y508F
PubMed Link: 23936469
Variant Present in the following documents:
  • Main text
  • pone.0070804.pdf
View BVdb publication page



Regulation of PTEN/Akt and MAP kinase signaling pathways by the ubiquitin ligase activators Ndfip1 and Ndfip2.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Mund, Thomas T; Pelham, Hugh R B HR
Publication Date: 2010-06-22

Variant appearance in text: PI3K: Y508F
PubMed Link: 20534535
Variant Present in the following documents:
  • Main text
View BVdb publication page



Epstein-Barr virus latent membrane protein 2A preferentially signals through the Src family kinase Lyn.

Journal Of Virology
Rovedo, Mark M; Longnecker, Richard R
Publication Date: 2008-09

Variant appearance in text: PI3K: Y508F
PubMed Link: 18579586
Variant Present in the following documents:
  • Main text
View BVdb publication page



The diverse functions of Src family kinases in macrophages.

Frontiers In Bioscience : A Journal And Virtual Library
Abram, Clare L CL; Lowell, Clifford A CA
Publication Date: 2008-05-01

Variant appearance in text: PI3K: Y508F
PubMed Link: 18508521
Variant Present in the following documents:
  • Main text
View BVdb publication page



Negative regulation of immunoglobulin E-dependent allergic responses by Lyn kinase.

The Journal Of Experimental Medicine
Odom, Sandra S; Gomez, Gregorio G; Kovarova, Martina M; Furumoto, Yasuko Y; Ryan, John J JJ; Wright, Harry V HV; Gonzalez-Espinosa, Claudia C; Hibbs, Margaret L ML; Harder, Kenneth W KW; Rivera, Juan J
Publication Date: 2004-06-07

Variant appearance in text: PI3K: Y508F
PubMed Link: 15173205
Variant Present in the following documents:
  • Main text
  • 20040382.pdf
View BVdb publication page



BANK regulates BCR-induced calcium mobilization by promoting tyrosine phosphorylation of IP(3) receptor.

The Embo Journal
Yokoyama, Kazumasa K; Su Ih, I-hsin IH; Tezuka, Tohru T; Yasuda, Tomoharu T; Mikoshiba, Katsuhiko K; Tarakhovsky, Alexander A; Yamamoto, Tadashi T
Publication Date: 2002-01-15

Variant appearance in text: PI3K: Y508F
PubMed Link: 11782428
Variant Present in the following documents:
  • Main text
View BVdb publication page