Publications:

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Integrative genomic and transcriptomic analyses illuminate the ontology of HER2-low breast carcinomas.

Genome Medicine

Berrino, Enrico E; Annaratone, Laura L; Bellomo, Sara Erika SE; Ferrero, Giulio G; Gagliardi, Amedeo A; Bragoni, Alberto A; Grassini, Dora D; Guarrera, Simonetta S; Parlato, Caterina C; Casorzo, Laura L; Panero, Mara M; Sarotto, Ivana I; Giordano, Silvia S; Cereda, Matteo M; Montemurro, Filippo F; Ponzone, Riccardo R; Crosetto, Nicola N; Naccarati, Alessio A; Sapino, Anna A; Marchiò, Caterina C

Publication Date: 2022-08-29

Variant appearance in text: PIK3CA: 1598C>T

PubMed Link: 36038884

Variant Present in the following documents:

• 13073_2022_1104_MOESM10_ESM.xlsx, sheet 1

View BVdb publication page

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GPCR-mediated PI3K pathway mutations in pediatric and adult thyroid cancer.

Oncotarget

Murugan, Avaniyapuram Kannan AK; Qasem, Ebtesam E; Al-Hindi, Hindi H; Alzahrani, Ali S AS

Publication Date: 2019-06-25

Variant appearance in text: PIK3CA: A533V

PubMed Link: 31289610

Variant Present in the following documents:

• Main text
• oncotarget-10-4107.pdf

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Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One

Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS

Publication Date: 2018

Variant appearance in text: PIK3CA: A533V

PubMed Link: 29698444

Variant Present in the following documents:

• pone.0196434.s001.xlsx, sheet 2
• pone.0196434.s001.xlsx, sheet 3

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Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients.

Nature Communications

Chen, Li L; Yang, Liu L; Yao, Ling L; Kuang, Xia-Ying XY; Zuo, Wen-Jia WJ; Li, Shan S; Qiao, Feng F; Liu, Yi-Rong YR; Cao, Zhi-Gang ZG; Zhou, Shu-Ling SL; Zhou, Xiao-Yan XY; Yang, Wen-Tao WT; Shi, Jin-Xiu JX; Huang, Wei W; Hu, Xin X; Shao, Zhi-Ming ZM

Publication Date: 2018-04-10

Variant appearance in text: PIK3CA: A533V

PubMed Link: 29636477

Variant Present in the following documents:

• 41467_2018_Article_3867.pdf
• 41467_2018_3867_MOESM1_ESM.pdf

View BVdb publication page

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Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications

Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ

Publication Date: 2017-05-11

Variant appearance in text: PIK3CA: A533V

PubMed Link: 28492226

Variant Present in the following documents:

• ncomms15086-s3.xlsx, sheet 1

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PIK3CA mutations are associated with reduced pathological complete response rates in primary HER2-positive breast cancer: pooled analysis of 967 patients from five prospective trials investigating lapatinib and trastuzumab.

Annals Of Oncology : Official Journal Of The European Society For Medical Oncology

Loibl, S S; Majewski, I I; Guarneri, V V; Nekljudova, V V; Holmes, E E; Bria, E E; Denkert, C C; Schem, C C; Sotiriou, C C; Loi, S S; Untch, M M; Conte, P P; Bernards, R R; Piccart, M M; von Minckwitz, G G; Baselga, J J

Publication Date: 2016-08

Variant appearance in text: PIK3CA: A533V

PubMed Link: 27177864

Variant Present in the following documents:

• Main text

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Erlotinib, erlotinib-sulindac versus placebo: a randomized, double-blind, placebo-controlled window trial in operable head and neck cancer.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Gross, Neil D ND; Bauman, Julie E JE; Gooding, William E WE; Denq, William W; Thomas, Sufi M SM; Wang, Lin L; Chiosea, Simion S; Hood, Brian L BL; Flint, Melanie S MS; Sun, Mai M; Conrads, Thomas P TP; Ferris, Robert L RL; Johnson, Jonas T JT; Kim, Seungwon S; Argiris, Athanassios A; Wirth, Lori L; Nikiforova, Marina N MN; Siegfried, Jill M JM; Grandis, Jennifer R JR

Publication Date: 2014-06-15

Variant appearance in text: PIK3CA: 1598C>T; A533V

PubMed Link: 24727329

Variant Present in the following documents:

• Main text

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Predicting the functional impact of protein mutations: application to cancer genomics.

Nucleic Acids Research

Reva, Boris B; Antipin, Yevgeniy Y; Sander, Chris C

Publication Date: 2011-09-01

Variant appearance in text: PIK3CA: A533V

PubMed Link: 21727090

Variant Present in the following documents:

• supp_gkr407_Supplement2_Table_SM1_COSMIC_mutations.xls, sheet 1

View BVdb publication page

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