Publications:

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Predictive Biomarkers for Immune Checkpoint Inhibitors in Metastatic Breast Cancer.

Cancer Medicine

Sivapiragasam, Abirami A; Ashok Kumar, Prashanth P; Sokol, Ethan S ES; Albacker, Lee A LA; Killian, Jonathan K JK; Ramkissoon, Shakti H SH; Huang, Richard S P RSP; Severson, Eric A EA; Brown, Charlotte A CA; Danziger, Natalie N; McGregor, Kimberly K; Ross, Jeffrey S JS

Publication Date: 2021-01

Variant appearance in text: PIK3CA: E545R

PubMed Link: 33314633

Variant Present in the following documents:

• CAM4-10-53-s003.xlsx, sheet 1

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Comparison of TCGA and GENIE genomic datasets for the detection of clinically actionable alterations in breast cancer.

Scientific Reports

Kaur, Pushpinder P; Porras, Tania B TB; Ring, Alexander A; Carpten, John D JD; Lang, Julie E JE

Publication Date: 2019-02-06

Variant appearance in text: PIK3CA: E545R

PubMed Link: 30728399

Variant Present in the following documents:

• 41598_2018_37574_MOESM1_ESM.pdf

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PI3K/mTOR inhibition potentiates and extends palbociclib activity in anaplastic thyroid cancer.

Endocrine-Related Cancer

Wong, Kristen K; Di Cristofano, Francesca F; Ranieri, Michela M; De Martino, Daniela D; Di Cristofano, Antonio A

Publication Date: 2019-04-01

Variant appearance in text: PIK3CA: E545R

PubMed Link: 30699064

Variant Present in the following documents:

• Main text

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The PIK3CA E542K and E545K mutations promote glycolysis and proliferation via induction of the β-catenin/SIRT3 signaling pathway in cervical cancer.

Journal Of Hematology & Oncology

Jiang, Wei W; He, Tiancong T; Liu, Shuai S; Zheng, Yingying Y; Xiang, Libing L; Pei, Xuan X; Wang, Ziliang Z; Yang, Huijuan H

Publication Date: 2018-12-14

Variant appearance in text: PIK3CA: E545R

PubMed Link: 30547809

Variant Present in the following documents:

• Main text
• 13045_2018_Article_674.pdf

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PI3K blockage synergizes with PLK1 inhibition preventing endoreduplication and enhancing apoptosis in anaplastic thyroid cancer.

Cancer Letters

De Martino, Daniela D; Yilmaz, Emrullah E; Orlacchio, Arturo A; Ranieri, Michela M; Zhao, Ke K; Di Cristofano, Antonio A

Publication Date: 2018-12-28

Variant appearance in text: PIK3CA: E545R

PubMed Link: 30243708

Variant Present in the following documents:

• Main text

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Kinetic and structural analyses reveal residues in phosphoinositide 3-kinase α that are critical for catalysis and substrate recognition.

The Journal Of Biological Chemistry

Maheshwari, Sweta S; Miller, Michelle S MS; O'Meally, Robert R; Cole, Robert N RN; Amzel, L Mario LM; Gabelli, Sandra B SB

Publication Date: 2017-08-18

Variant appearance in text: PI3K: E545R

PubMed Link: 28676499

Variant Present in the following documents:

• Main text

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Molecular profiling of lung adenosquamous carcinoma: hybrid or genuine type?

Oncotarget

Vassella, Erik E; Langsch, Stephanie S; Dettmer, Matthias S MS; Schlup, Cornelia C; Neuenschwander, Maja M; Frattini, Milo M; Gugger, Mathias M; Schäfer, Stephan C SC

Publication Date: 2015-09-15

Variant appearance in text: PIK3CA: E545R

PubMed Link: 26068980

Variant Present in the following documents:

• oncotarget-06-23905-s001.pdf

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Use of multivariate analysis to suggest a new molecular classification of colorectal cancer.

The Journal Of Pathology

Domingo, Enric E; Ramamoorthy, Rajarajan R; Oukrif, Dahmane D; Rosmarin, Daniel D; Presz, Michal M; Wang, Haitao H; Pulker, Hannah H; Lockstone, Helen H; Hveem, Tarjei T; Cranston, Treena T; Danielsen, Havard H; Novelli, Marco M; Davidson, Brian B; Xu, Zheng-Zhou ZZ; Molloy, Peter P; Johnstone, Elaine E; Holmes, Christopher C; Midgley, Rachel R; Kerr, David D; Sieber, Oliver O; Tomlinson, Ian I

Publication Date: 2013-02

Variant appearance in text: PIK3CA: E545R

PubMed Link: 23165447

Variant Present in the following documents:

• path0229-0441-FigureS1.pdf

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