PIK3CA c.1647T>G ;(p.D549E)

Variant ID: 3-178936105-T-G

NM_006218.2(PIK3CA):c.1647T>G;(p.D549E)

This variant was identified in 2 publications

View GRCh38 version.




Publications:


Insights into the mechanism of the PIK3CA E545K activating mutation using MD simulations.

Scientific Reports
Leontiadou, Hari H; Galdadas, Ioannis I; Athanasiou, Christina C; Cournia, Zoe Z
Publication Date: 2018-10-19

Variant appearance in text: PIK3CA: D549E
PubMed Link: 30341384
Variant Present in the following documents:
  • 41598_2018_27044_MOESM1_ESM.pdf
View BVdb publication page



A combined oncogenic pathway signature of BRAF, KRAS and PI3KCA mutation improves colorectal cancer classification and cetuximab treatment prediction.

Gut
Tian, Sun S; Simon, Iris I; Moreno, Victor V; Roepman, Paul P; Tabernero, Josep J; Snel, Mireille M; van't Veer, Laura L; Salazar, Ramon R; Bernards, Rene R; Capella, Gabriel G
Publication Date: 2013-04

Variant appearance in text: PIK3CA: D549E
PubMed Link: 22798500
Variant Present in the following documents:
  • Main text
  • gutjnl-2012-302423.pdf
View BVdb publication page