Publications:

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Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective.

Acs Chemical Neuroscience

Ong, Han Wee HW; Liang, Yi Y; Richardson, William W; Lowry, Emily R ER; Wells, Carrow I CI; Chen, Xiangrong X; Silvestre, Margaux M; Dempster, Kelvin K; Silvaroli, Josie A JA; Smith, Jeffery L JL; Wichterle, Hynek H; Pabla, Navjot S NS; Ultanir, Sila K SK; Bullock, Alex N AN; Drewry, David H DH; Axtman, Alison D AD

Publication Date: 2023-04-21

Variant appearance in text: PIK3CA: V559D

PubMed Link: 37084253

Variant Present in the following documents:

• cn3c00135_si_001.pdf

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Deep Annotation of Donated Chemical Probes (DCP) in Organotypic Human Liver Cultures and Patient-Derived Organoids from Tumor and Normal Colorectum.

Acs Chemical Biology

Tredup, Claudia C; Ndreshkjana, Benardina B; Schneider, Natalie S NS; Tjaden, Amelie A; Kemas, Aurino M AM; Youhanna, Sonia S; Lauschke, Volker M VM; Berger, Benedict-Tilman BT; Krämer, Andreas A; Berger, Lena M LM; Röhm, Sandra S; Knapp, Stefan S; Farin, Henner F HF; Müller, Susanne S

Publication Date: 2023-03-21

Variant appearance in text: PIK3CA: V559D

PubMed Link: 36944371

Variant Present in the following documents:

• cb2c00877_si_002.xlsx, sheet 1

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KLF5 inhibition overcomes oxaliplatin resistance in patient-derived colorectal cancer organoids by restoring apoptotic response.

Cell Death & Disease

Shen, Xiaohui X; Zhang, Yuchen Y; Xu, Zhuoqing Z; Gao, Han H; Feng, Wenqing W; Li, Wenchang W; Miao, Yiming Y; Xu, Zifeng Z; Zong, Yaping Y; Zhao, Jingkun J; Lu, Aiguo A

Publication Date: 2022-04-05

Variant appearance in text: PI3K: V559D

PubMed Link: 35379798

Variant Present in the following documents:

• 41419_2022_4773_MOESM9_ESM.xlsx, sheet 1

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Identification of 4-phenylquinolin-2(1H)-one as a specific allosteric inhibitor of Akt.

Scientific Reports

Huang, Bill X BX; Newcomer, Kenny K; Kevala, Karl K; Barnaeva, Elena E; Zheng, Wei W; Hu, Xin X; Patnaik, Samarjit S; Southall, Noel N; Marugan, Juan J; Ferrer, Marc M; Kim, Hee-Yong HY

Publication Date: 2017-09-15

Variant appearance in text: PIK3CA: V559D

PubMed Link: 28916818

Variant Present in the following documents:

• 41598_2017_11870_MOESM1_ESM.pdf

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Possible prognostic and therapeutic significance of c-Kit expression, mast cell count and microvessel density in renal cell carcinoma.

International Journal Of Molecular Sciences

Marech, Ilaria I; Gadaleta, Cosmo Damiano CD; Ranieri, Girolamo G

Publication Date: 2014-07-23

Variant appearance in text: PI3K: V559D

PubMed Link: 25056544

Variant Present in the following documents:

• Main text
• ijms-15-13060.pdf

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Oncogene mutational profile in nasopharyngeal carcinoma.

Oncotargets And Therapy

Zhang, Zi-Chen ZC; Fu, Sha S; Wang, Fang F; Wang, Hai-Yun HY; Zeng, Yi-Xin YX; Shao, Jian-Yong JY

Publication Date: 2014

Variant appearance in text: PIK3CA: V559D

PubMed Link: 24672248

Variant Present in the following documents:

• ott-7-457.pdf

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A rapid, sensitive, reproducible and cost-effective method for mutation profiling of colon cancer and metastatic lymph nodes.

Bmc Cancer

Fumagalli, Debora D; Gavin, Patrick G PG; Taniyama, Yusuke Y; Kim, Seung-Il SI; Choi, Hyun-Joo HJ; Paik, Soonmyung S; Pogue-Geile, Katherine L KL

Publication Date: 2010-03-16

Variant appearance in text: PIK3CA: V559D

PubMed Link: 20233444

Variant Present in the following documents:

• Main text
• 1471-2407-10-101.pdf

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