Publications:

Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology.

Nature Medicine

Sturm, Dominik D; Capper, David D; Andreiuolo, Felipe F; Gessi, Marco M; Kölsche, Christian C; Reinhardt, Annekathrin A; Sievers, Philipp P; Wefers, Annika K AK; Ebrahimi, Azadeh A; Suwala, Abigail K AK; Gielen, Gerrit H GH; Sill, Martin M; Schrimpf, Daniel D; Stichel, Damian D; Hovestadt, Volker V; Daenekas, Bjarne B; Rode, Agata A; Hamelmann, Stefan S; Previti, Christopher C; Jäger, Natalie N; Buchhalter, Ivo I; Blattner-Johnson, Mirjam M; Jones, Barbara C BC; Warmuth-Metz, Monika M; Bison, Brigitte B; Grund, Kerstin K; Sutter, Christian C; Hirsch, Steffen S; Dikow, Nicola N; Hasselblatt, Martin M; Schüller, Ulrich U; Gerber, Nicolas U NU; White, Christine L CL; Buntine, Molly K MK; Kinross, Kathryn K; Algar, Elizabeth M EM; Hansford, Jordan R JR; Gottardo, Nicholas G NG; Hernáiz Driever, Pablo P; Gnekow, Astrid A; Witt, Olaf O; Müller, Hermann L HL; Calaminus, Gabriele G; Fleischhack, Gudrun G; Kordes, Uwe U; Mynarek, Martin M; Rutkowski, Stefan S; Frühwald, Michael C MC; Kramm, Christof M CM; von Deimling, Andreas A; Pietsch, Torsten T; Sahm, Felix F; Pfister, Stefan M SM; Jones, David T W DTW

Publication Date: 2023-03-16

Variant appearance in text: PIK3CA: K567E

PubMed Link: 36928815

Variant Present in the following documents:

• 41591_2023_2255_MOESM3_ESM.xlsx, sheet 5

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Somatic PIK3R1 variation as a cause of vascular malformations and overgrowth.

Genetics In Medicine : Official Journal Of The American College Of Medical Genetics

Cottrell, Catherine E CE; Bender, Nicole R NR; Zimmermann, Michael T MT; Heusel, Jonathan W JW; Corliss, Meagan M; Evenson, Michael J MJ; Magrini, Vincent V; Corsmeier, Donald J DJ; Avenarius, Matthew M; Dudley, Jeffrey N JN; Johnston, Jennifer J JJ; Lindhurst, Marjorie J MJ; Vigh-Conrad, Katinka K; Davies, Olivia M T OMT; Coughlin, Carrie C CC; Frieden, Ilona J IJ; Tollefson, Megha M; Zaenglein, Andrea L AL; Ciliberto, Heather H; Tosi, Laura L LL; Semple, Robert K RK; Biesecker, Leslie G LG; Drolet, Beth A BA

Publication Date: 2021-10

Variant appearance in text: PI3K: 1699A>G

PubMed Link: 34040190

Variant Present in the following documents:

• Main text

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Characterization of the genomic landscape and actionable mutations in Chinese breast cancers by clinical sequencing.

Nature Communications

Lang, Guan-Tian GT; Jiang, Yi-Zhou YZ; Shi, Jin-Xiu JX; Yang, Fan F; Li, Xiao-Guang XG; Pei, Yu-Chen YC; Zhang, Chen-Hui CH; Ma, Ding D; Xiao, Yi Y; Hu, Peng-Chen PC; Wang, Hai H; Yang, Yun-Song YS; Guo, Lin-Wei LW; Lu, Xun-Xi XX; Xue, Meng-Zhu MZ; Wang, Peng P; Cao, A-Yong AY; Ling, Hong H; Wang, Zhong-Hua ZH; Yu, Ke-Da KD; Di, Gen-Hong GH; Li, Da-Qiang DQ; Wang, Yun-Jin YJ; Yu, Ying Y; Shi, Le-Ming LM; Hu, Xin X; Huang, Wei W; Shao, Zhi-Ming ZM

Publication Date: 2020-11-10

Variant appearance in text: PIK3CA: K567E

PubMed Link: 33173047

Variant Present in the following documents:

• 41467_2020_19342_MOESM7_ESM.xlsx, sheet 1

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Preclinical evaluation and reverse phase protein Array-based profiling of PI3K and MEK inhibitors in endometrial carcinoma in vitro.

Bmc Cancer

Aslan, Ozlem O; Cremona, Mattia M; Morgan, Clare C; Cheung, Lydia W LW; Mills, Gordon B GB; Hennessy, Bryan T BT

Publication Date: 2018-02-09

Variant appearance in text: PIK3CA: K567E

PubMed Link: 29426295

Variant Present in the following documents:

• Main text
• 12885_2018_Article_4035.pdf

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Pharmacokinetic, pharmacodynamic and biomarker evaluation of transforming growth factor-β receptor I kinase inhibitor, galunisertib, in phase 1 study in patients with advanced cancer.

Investigational New Drugs

Rodón, Jordi J; Carducci, Michael M; Sepulveda-Sánchez, Juan M JM; Azaro, Analía A; Calvo, Emiliano E; Seoane, Joan J; Braña, Irene I; Sicart, Elisabet E; Gueorguieva, Ivelina I; Cleverly, Ann A; Pillay, N Sokalingum NS; Desaiah, Durisala D; Estrem, Shawn T ST; Paz-Ares, Luis L; Holdhoff, Matthias M; Blakeley, Jaishri J; Lahn, Michael M MM; Baselga, Jose J

Publication Date: 2015-04

Variant appearance in text: PIK3CA: K567E

PubMed Link: 25529192

Variant Present in the following documents:

• Main text
• 10637_2014_Article_192.pdf

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