Publications:

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FcγRIIb-SHIP2 axis links Aβ to tau pathology by disrupting phosphoinositide metabolism in Alzheimer's disease model.

Elife

Kam, Tae-In TI; Park, Hyejin H; Gwon, Youngdae Y; Song, Sungmin S; Kim, Seo-Hyun SH; Moon, Seo Won SW; Jo, Dong-Gyu DG; Jung, Yong-Keun YK

Publication Date: 2016-11-11

Variant appearance in text: PI3K: D608A

PubMed Link: 27834631

Variant Present in the following documents:

• Main text

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5'-Inositol phosphatase SHIP2 recruits Mena to stabilize invadopodia for cancer cell invasion.

The Journal Of Cell Biology

Rajadurai, Charles V CV; Havrylov, Serhiy S; Coelho, Paula P PP; Ratcliffe, Colin D H CD; Zaoui, Kossay K; Huang, Bruce H BH; Monast, Anie A; Chughtai, Naila N; Sangwan, Veena V; Gertler, Frank B FB; Siegel, Peter M PM; Park, Morag M

Publication Date: 2016-09-12

Variant appearance in text: PI3K: D608A

PubMed Link: 27597754

Variant Present in the following documents:

• Main text
• JCB_201501003.pdf

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Tks5 and SHIP2 regulate invadopodium maturation, but not initiation, in breast carcinoma cells.

Current Biology : Cb

Sharma, Ved P VP; Eddy, Robert R; Entenberg, David D; Kai, Masayuki M; Gertler, Frank B FB; Condeelis, John J

Publication Date: 2013-11-04

Variant appearance in text: PI3K: D608A

PubMed Link: 24206842

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The inositol 5-phosphatase SHIP2 is an effector of RhoA and is involved in cell polarity and migration.

Molecular Biology Of The Cell

Kato, Katsuhiro K; Yazawa, Tsubasa T; Taki, Kentaro K; Mori, Kazutaka K; Wang, Shujie S; Nishioka, Tomoki T; Hamaguchi, Tomonari T; Itoh, Toshiki T; Takenawa, Tadaomi T; Kataoka, Chikako C; Matsuura, Yoshiharu Y; Amano, Mutsuki M; Murohara, Toyoaki T; Kaibuchi, Kozo K

Publication Date: 2012-07

Variant appearance in text: PI3K: D608A

PubMed Link: 22593208

Variant Present in the following documents:

• Main text
• 2593.pdf

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Serum withdrawal-induced accumulation of phosphoinositide 3-kinase lipids in differentiating 3T3-L6 myoblasts: distinct roles for Ship2 and PTEN.

Molecular And Cellular Biology

Mandl, Adel A; Sarkes, Deborah D; Carricaburu, Valerie V; Jung, Vanessa V; Rameh, Lucia L

Publication Date: 2007-12

Variant appearance in text: PI3K: D608A

PubMed Link: 17893321

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5' phospholipid phosphatase SHIP-2 causes protein kinase B inactivation and cell cycle arrest in glioblastoma cells.

Molecular And Cellular Biology

Taylor, V V; Wong, M M; Brandts, C C; Reilly, L L; Dean, N M NM; Cowsert, L M LM; Moodie, S S; Stokoe, D D

Publication Date: 2000-09

Variant appearance in text: PI3K: D608A

PubMed Link: 10958682

Variant Present in the following documents:

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