Publications:

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PROTACs in the Management of Prostate Cancer.

Molecules (Basel, Switzerland)

Yedla, Poornachandra P; Babalghith, Ahmed O AO; Andra, Vindhya Vasini VV; Syed, Riyaz R

Publication Date: 2023-04-25

Variant appearance in text: PI3K: L702H

PubMed Link: 37175108

Variant Present in the following documents:

• Main text
• molecules-28-03698.pdf

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Androgen Metabolism and Response in Prostate Cancer Anti-Androgen Therapy Resistance.

International Journal Of Molecular Sciences

Zhang, Haozhe H; Zhou, Yi Y; Xing, Zengzhen Z; Sah, Rajiv Kumar RK; Hu, Junqi J; Hu, Hailiang H

Publication Date: 2022-11-04

Variant appearance in text: PI3K: L702H

PubMed Link: 36362304

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• Main text
• ijms-23-13521.pdf

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Multisite gynecologic endometrioid adenocarcinomas: Can mutation profiling be used to distinguish synchronous primary cancers from metastases?

Gynecologic Oncology Reports

Barnes, Dominique D; Mohammad, Nissreen N; Hoang, Lien L; Anglesio, Michael M; Hollis, Robert L RL; Gourley, Charlie C; Stuart, Heather C HC; Carey, Mark S MS; Stuart, Gavin C E GCE

Publication Date: 2022-12

Variant appearance in text: PIK3CA: L702H

PubMed Link: 36299398

Variant Present in the following documents:

• Main text
• main.pdf

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Overcoming Obstacles in Liquid Biopsy Developments for Prostate Cancer.

Oncotargets And Therapy

Jang, Albert A; Rauterkus, Grant P GP; Vaishampayan, Ulka N UN; Barata, Pedro C PC

Publication Date: 2022

Variant appearance in text: PI3K: L702H

PubMed Link: 36051571

Variant Present in the following documents:

• Main text
• ott-15-897.pdf

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Resistance to second generation antiandrogens in prostate cancer: pathways and mechanisms.

Cancer Drug Resistance (Alhambra, Calif.)

Verma, Shiv S; Prajapati, Kumari Sunita KS; Kushwaha, Prem Prakash PP; Shuaib, Mohd M; Kumar Singh, Atul A; Kumar, Shashank S; Gupta, Sanjay S

Publication Date: 2020

Variant appearance in text: PI3K: L702H

PubMed Link: 35582225

Variant Present in the following documents:

• cdr-3-742.pdf

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Systematic review and meta-analysis of genomic alterations in acral melanoma.

Pigment Cell & Melanoma Research

Broit, Natasa N; Johansson, Peter A PA; Rodgers, Chloe B CB; Walpole, Sebastian T ST; Hayward, Nicholas K NK; Pritchard, Antonia L AL

Publication Date: 2022-05

Variant appearance in text: PIK3CA: L702H

PubMed Link: 35229492

Variant Present in the following documents:

• PCMR-35-369-s003.xlsx, sheet 12

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Genomic attributes of homology-directed DNA repair deficiency in metastatic prostate cancer.

Jci Insight

De Sarkar, Navonil N; Dasgupta, Sayan S; Chatterjee, Payel P; Coleman, Ilsa I; Ha, Gavin G; Ang, Lisa S LS; Kohlbrenner, Emily A EA; Frank, Sander B SB; Nunez, Talina A TA; Salipante, Stephen J SJ; Corey, Eva E; Morrissey, Colm C; Van Allen, Eliezer E; Schweizer, Michael T MT; Haffner, Michael C MC; Patel, Radhika R; Hanratty, Brian B; Lucas, Jared M JM; Dumpit, Ruth F RF; Pritchard, Colin C CC; Montgomery, Robert B RB; Nelson, Peter S PS

Publication Date: 2021-12-08

Variant appearance in text: PIK3CA: L702H

PubMed Link: 34877933

Variant Present in the following documents:

• jciinsight-6-152789-s069.xlsx, sheet 8

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Androgen Receptor Signaling in Prostate Cancer and Therapeutic Strategies.

Cancers

Jacob, Aasems A; Raj, Rishi R; Allison, Derek B DB; Myint, Zin W ZW

Publication Date: 2021-10-28

Variant appearance in text: PI3K: L702H

PubMed Link: 34771580

Variant Present in the following documents:

• Main text
• cancers-13-05417.pdf

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Molecular Characterization of Prostate Cancers in the Precision Medicine Era.

Cancers

Giunta, Emilio Francesco EF; Annaratone, Laura L; Bollito, Enrico E; Porpiglia, Francesco F; Cereda, Matteo M; Banna, Giuseppe Luigi GL; Mosca, Alessandra A; Marchiò, Caterina C; Rescigno, Pasquale P

Publication Date: 2021-09-24

Variant appearance in text: PI3K: L702H

PubMed Link: 34638258

Variant Present in the following documents:

• Main text
• cancers-13-04771.pdf

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: PIK3CA: L702H

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

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Breaking androgen receptor addiction of prostate cancer by targeting different functional domains in the treatment of advanced disease.

Translational Oncology

Maylin, Zoe R ZR; Nicolescu, Radu Cb RC; Pandha, Hardev H; Asim, Mohammad M

Publication Date: 2021-08

Variant appearance in text: PI3K: L702H

PubMed Link: 33993099

Variant Present in the following documents:

• Main text
• main.pdf

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Signaling Pathways in Cancer: Therapeutic Targets, Combinatorial Treatments, and New Developments.

Cells

Yip, Hon Yan Kelvin HYK; Papa, Antonella A

Publication Date: 2021-03-16

Variant appearance in text: PIK3CA: L702H

PubMed Link: 33809714

Variant Present in the following documents:

• Main text
• cells-10-00659.pdf

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Non-Coding RNAs Set a New Phenotypic Frontier in Prostate Cancer Metastasis and Resistance.

International Journal Of Molecular Sciences

Altschuler, Joshua J; Stockert, Jennifer A JA; Kyprianou, Natasha N

Publication Date: 2021-02-20

Variant appearance in text: PI3K: L702H

PubMed Link: 33672595

Variant Present in the following documents:

• Main text
• ijms-22-02100.pdf

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Preclinical Models in Prostate Cancer: Resistance to AR Targeting Therapies in Prostate Cancer.

Cancers

Devlies, Wout W; Handle, Florian F; Devos, Gaëtan G; Joniau, Steven S; Claessens, Frank F

Publication Date: 2021-02-22

Variant appearance in text: PI3K: L702H

PubMed Link: 33671614

Variant Present in the following documents:

• Main text

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Assessment of Clinical Benefit of Integrative Genomic Profiling in Advanced Solid Tumors.

Jama Oncology

Cobain, Erin F EF; Wu, Yi-Mi YM; Vats, Pankaj P; Chugh, Rashmi R; Worden, Francis F; Smith, David C DC; Schuetze, Scott M SM; Zalupski, Mark M MM; Sahai, Vaibhav V; Alva, Ajjai A; Schott, Anne F AF; Caram, Megan E V MEV; Hayes, Daniel F DF; Stoffel, Elena M EM; Jacobs, Michelle F MF; Kumar-Sinha, Chandan C; Cao, Xuhong X; Wang, Rui R; Lucas, David D; Ning, Yu Y; Rabban, Erica E; Bell, Janice J; Camelo-Piragua, Sandra S; Udager, Aaron M AM; Cieslik, Marcin M; Lonigro, Robert J RJ; Kunju, Lakshmi P LP; Robinson, Dan R DR; Talpaz, Moshe M; Chinnaiyan, Arul M AM

Publication Date: 2021-04-01

Variant appearance in text: PIK3CA: L702H

PubMed Link: 33630025

Variant Present in the following documents:

• jamaoncol-e207987-s004.xlsx, sheet 2

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New Prognostic Biomarkers in Metastatic Castration-Resistant Prostate Cancer.

Cells

Conteduca, Vincenza V; Mosca, Alessandra A; Brighi, Nicole N; de Giorgi, Ugo U; Rescigno, Pasquale P

Publication Date: 2021-01-19

Variant appearance in text: PI3K: L702H

PubMed Link: 33478015

Variant Present in the following documents:

• Main text
• cells-10-00193.pdf

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Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: PIK3CA: L702H

PubMed Link: 33397889

Variant Present in the following documents:

• Main text

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Clinical Actionability of the Genomic Landscape of Metastatic Castration Resistant Prostate Cancer.

Cells

Devlies, Wout W; Eckstein, Markus M; Cimadamore, Alessia A; Devos, Gaëtan G; Moris, Lisa L; Van den Broeck, Thomas T; Montironi, Rodolfo R; Joniau, Steven S; Claessens, Frank F; Gevaert, Thomas T

Publication Date: 2020-11-17

Variant appearance in text: PI3K: L702H

PubMed Link: 33212909

Variant Present in the following documents:

• Main text

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Genomic Instability in Circulating Tumor Cells.

Cancers

Freitas, Monique Oliveira MO; Gartner, John J; Rangel-Pozzo, Aline A; Mai, Sabine S

Publication Date: 2020-10-16

Variant appearance in text: PIK3CA: L702H

PubMed Link: 33081135

Variant Present in the following documents:

• Main text
• cancers-12-03001.pdf

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Clinical Applications of Molecular Biomarkers in Prostate Cancer.

Cancers

Couñago, Felipe F; López-Campos, Fernando F; Díaz-Gavela, Ana Aurora AA; Almagro, Elena E; Fenández-Pascual, Esaú E; Henríquez, Iván I; Lozano, Rebeca R; Linares Espinós, Estefanía E; Gómez-Iturriaga, Alfonso A; de Velasco, Guillermo G; Quintana Franco, Luis Miguel LM; Rodríguez-Melcón, Ignacio I; López-Torrecilla, José J; Spratt, Daniel E DE; Guerrero, Luis Leonardo LL; Martínez-Salamanca, Juan Ignacio JI; Del Cerro, Elia E

Publication Date: 2020-06-12

Variant appearance in text: PI3K: L702H

PubMed Link: 32545454

Variant Present in the following documents:

• cancers-12-01550.pdf

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Phase and context shape the function of composite oncogenic mutations.

Nature

Gorelick, Alexander N AN; Sánchez-Rivera, Francisco J FJ; Cai, Yanyan Y; Bielski, Craig M CM; Biederstedt, Evan E; Jonsson, Philip P; Richards, Allison L AL; Vasan, Neil N; Penson, Alexander V AV; Friedman, Noah D ND; Ho, Yu-Jui YJ; Baslan, Timour T; Bandlamudi, Chaitanya C; Scaltriti, Maurizio M; Schultz, Nikolaus N; Lowe, Scott W SW; Reznik, Ed E; Taylor, Barry S BS

Publication Date: 2020-06

Variant appearance in text: PIK3CA: L702H

PubMed Link: 32461694

Variant Present in the following documents:

• NIHMS1582596-supplement-1582596_Supp_Tab1-5.xlsx, sheet 2

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Comprehensive Analysis of AR Alterations in Circulating Tumor DNA from Patients with Advanced Prostate Cancer.

The Oncologist

Ledet, Elisa M EM; Lilly, Michael B MB; Sonpavde, Guru G; Lin, Edwin E; Nussenzveig, Roberto H RH; Barata, Pedro C PC; Yandell, Mark M; Nagy, Rebecca J RJ; Kiedrowski, Lesli L; Agarwal, Neeraj N; Sartor, Oliver O

Publication Date: 2020-04

Variant appearance in text: PIK3CA: L702H

PubMed Link: 32297439

Variant Present in the following documents:

• Main text

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Clinical and genomic insights into circulating tumor DNA-based alterations across the spectrum of metastatic hormone-sensitive and castrate-resistant prostate cancer.

Ebiomedicine

Kohli, Manish M; Tan, Winston W; Zheng, Tiantian T; Wang, Amy A; Montesinos, Carlos C; Wong, Calven C; Du, Pan P; Jia, Shidong S; Yadav, Siddhartha S; Horvath, Lisa G LG; Mahon, Kate L KL; Kwan, Edmond M EM; Fettke, Heidi H; Yu, Jianjun J; Azad, Arun A AA

Publication Date: 2020-04

Variant appearance in text: PIK3CA: Leu702His

PubMed Link: 32268276

Variant Present in the following documents:

• mmc5.xlsx, sheet 2

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Circulating tumor DNA analysis in the era of precision oncology.

Oncotarget

Said, Rabih R; Guibert, Nicolas N; Oxnard, Geoffrey R GR; Tsimberidou, Apostolia M AM

Publication Date: 2020-01-14

Variant appearance in text: PI3K: L702H

PubMed Link: 32010431

Variant Present in the following documents:

• Main text
• oncotarget-11-188.pdf

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Therapies Targeted to Androgen Receptor Signaling Axis in Prostate Cancer: Progress, Challenges, and Hope.

Cancers

Saranyutanon, Sirin S; Srivastava, Sanjeev Kumar SK; Pai, Sachin S; Singh, Seema S; Singh, Ajay Pratap AP

Publication Date: 2019-12-23

Variant appearance in text: PI3K: L702H

PubMed Link: 31877956

Variant Present in the following documents:

• Main text

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Genomics of lethal prostate cancer at diagnosis and castration resistance.

The Journal Of Clinical Investigation

Mateo, Joaquin J; Seed, George G; Bertan, Claudia C; Rescigno, Pasquale P; Dolling, David D; Figueiredo, Ines I; Miranda, Susana S; Nava Rodrigues, Daniel D; Gurel, Bora B; Clarke, Matthew M; Atkin, Mark M; Chandler, Rob R; Messina, Carlo C; Sumanasuriya, Semini S; Bianchini, Diletta D; Barrero, Maialen M; Petermolo, Antonella A; Zafeiriou, Zafeiris Z; Fontes, Mariane M; Perez-Lopez, Raquel R; Tunariu, Nina N; Fulton, Ben B; Jones, Robert R; McGovern, Ursula U; Ralph, Christy C; Varughese, Mohini M; Parikh, Omi O; Jain, Suneil S; Elliott, Tony T; Sandhu, Shahneen S; Porta, Nuria N; Hall, Emma E; Yuan, Wei W; Carreira, Suzanne S; de Bono, Johann S JS

Publication Date: 2020-04-01

Variant appearance in text: PIK3CA: L702H

PubMed Link: 31874108

Variant Present in the following documents:

• jci-130-132031-s102.xlsx, sheet 2

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The Role Of Circulating Tumor DNA In Therapeutic Resistance.

Oncotargets And Therapy

Xu, Chenxin C; Cao, Haixia H; Shi, Chen C; Feng, Jifeng J

Publication Date: 2019

Variant appearance in text: PI3K: L702H

PubMed Link: 31807023

Variant Present in the following documents:

• Main text
• ott-12-9459.pdf

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Comprehensive Analysis of AR Alterations in Circulating Tumor DNA from Patients with Advanced Prostate Cancer.

The Oncologist

Ledet, Elisa M EM; Lilly, Michael B MB; Sonpavde, Guru G; Lin, Edwin E; Nussenzveig, Roberto H RH; Barata, Pedro C PC; Yandell, Mark M; Nagy, Rebecca J RJ; Kiedrowski, Lesli L; Agarwal, Neeraj N; Sartor, Oliver O

Publication Date: 2019-11-11

Variant appearance in text: PIK3CA: L702H

PubMed Link: 31712304

Variant Present in the following documents:

• Main text

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Pan-cancer whole-genome analyses of metastatic solid tumours.

Nature

Priestley, Peter P; Baber, Jonathan J; Lolkema, Martijn P MP; Steeghs, Neeltje N; de Bruijn, Ewart E; Shale, Charles C; Duyvesteyn, Korneel K; Haidari, Susan S; van Hoeck, Arne A; Onstenk, Wendy W; Roepman, Paul P; Voda, Mircea M; Bloemendal, Haiko J HJ; Tjan-Heijnen, Vivianne C G VCG; van Herpen, Carla M L CML; Labots, Mariette M; Witteveen, Petronella O PO; Smit, Egbert F EF; Sleijfer, Stefan S; Voest, Emile E EE; Cuppen, Edwin E

Publication Date: 2019-11

Variant appearance in text: PIK3CA: Leu702His

PubMed Link: 31645765

Variant Present in the following documents:

• 41586_2019_1689_MOESM10_ESM.xlsx, sheet 1

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Towards precision oncology in advanced prostate cancer.

Nature Reviews. Urology

Ku, Sheng-Yu SY; Gleave, Martin E ME; Beltran, Himisha H

Publication Date: 2019-11

Variant appearance in text: PI3K: L702H

PubMed Link: 31591549

Variant Present in the following documents:

• Main text

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Analysis of error profiles in deep next-generation sequencing data.

Genome Biology

Ma, Xiaotu X; Shao, Ying Y; Tian, Liqing L; Flasch, Diane A DA; Mulder, Heather L HL; Edmonson, Michael N MN; Liu, Yu Y; Chen, Xiang X; Newman, Scott S; Nakitandwe, Joy J; Li, Yongjin Y; Li, Benshang B; Shen, Shuhong S; Wang, Zhaoming Z; Shurtleff, Sheila S; Robison, Leslie L LL; Levy, Shawn S; Easton, John J; Zhang, Jinghui J

Publication Date: 2019-03-14

Variant appearance in text: PIK3CA: L702H

PubMed Link: 30867008

Variant Present in the following documents:

• 13059_2019_1659_MOESM1_ESM.xlsx, sheet 7

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Molecular Mechanisms Related to Hormone Inhibition Resistance in Prostate Cancer.

Cells

Mollica, Veronica V; Di Nunno, Vincenzo V; Cimadamore, Alessia A; Lopez-Beltran, Antonio A; Cheng, Liang L; Santoni, Matteo M; Scarpelli, Marina M; Montironi, Rodolfo R; Massari, Francesco F

Publication Date: 2019-01-11

Variant appearance in text: PI3K: L702H

PubMed Link: 30642011

Variant Present in the following documents:

• Main text

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Enzalutamide-resistant castration-resistant prostate cancer: challenges and solutions.

Oncotargets And Therapy

Tucci, Marcello M; Zichi, Clizia C; Buttigliero, Consuelo C; Vignani, Francesca F; Scagliotti, Giorgio V GV; Di Maio, Massimo M

Publication Date: 2018

Variant appearance in text: PI3K: L702H

PubMed Link: 30425524

Variant Present in the following documents:

• Main text
• ott-11-7353.pdf

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Castration-Resistant Prostate Cancer Refractory to Second-Generation Androgen Receptor Axis-Targeted Agents: Opportunities and Challenges.

Cancers

Kita, Yuki Y; Goto, Takayuki T; Akamatsu, Shusuke S; Yamasaki, Toshinari T; Inoue, Takahiro T; Ogawa, Osamu O; Kobayashi, Takashi T

Publication Date: 2018-09-21

Variant appearance in text: PI3K: L702H

PubMed Link: 30248934

Variant Present in the following documents:

• Main text

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Role of Androgen Receptor in Prostate Cancer: A Review.

The World Journal Of Men'S Health

Fujita, Kazutoshi K; Nonomura, Norio N

Publication Date: 2019-09

Variant appearance in text: PI3K: L702H

PubMed Link: 30209899

Variant Present in the following documents:

• Main text
• wjmh-37-288.pdf

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TP53 Outperforms Other Androgen Receptor Biomarkers to Predict Abiraterone or Enzalutamide Outcome in Metastatic Castration-Resistant Prostate Cancer.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

De Laere, Bram B; Oeyen, Steffi S; Mayrhofer, Markus M; Whitington, Tom T; van Dam, Pieter-Jan PJ; Van Oyen, Peter P; Ghysel, Christophe C; Ampe, Jozef J; Ost, Piet P; Demey, Wim W; Hoekx, Lucien L; Schrijvers, Dirk D; Brouwers, Barbara B; Lybaert, Willem W; Everaert, Els G EG; De Maeseneer, Daan D; Strijbos, Michiel M; Bols, Alain A; Fransis, Karen K; Beije, Nick N; de Kruijff, Inge E IE; van Dam, Valerie V; Brouwer, Anja A; Goossens, Dirk D; Heyrman, Lien L; Van den Eynden, Gert G GG; Rutten, Annemie A; Del Favero, Jurgen J; Rantalainen, Mattias M; Rajan, Prabhakar P; Sleijfer, Stefan S; Ullén, Anders A; Yachnin, Jeffrey J; Grönberg, Henrik H; Van Laere, Steven J SJ; Lindberg, Johan J; Dirix, Luc Y LY

Publication Date: 2019-03-15

Variant appearance in text: PI3K: L702H

PubMed Link: 30209161

Variant Present in the following documents:

• Main text

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Liquid biopsy approach in the management of prostate cancer.

Translational Research : The Journal Of Laboratory And Clinical Medicine

Riaz, Irbaz Bin IB; Wang, Liang L; Kohli, Manish M

Publication Date: 2018-11

Variant appearance in text: PI3K: L702H

PubMed Link: 29936077

Variant Present in the following documents:

• Main text

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Molecular and cellular mechanisms of castration resistant prostate cancer.

Oncology Letters

Huang, Yiqiao Y; Jiang, Xianhan X; Liang, Xue X; Jiang, Ganggang G

Publication Date: 2018-05

Variant appearance in text: PI3K: L702H

PubMed Link: 29616091

Variant Present in the following documents:

• Main text
• ol-15-05-6063.pdf

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Utility of cell-free nucleic acid and circulating tumor cell analyses in prostate cancer.

Asian Journal Of Andrology

Gourdin, Theodore T; Sonpavde, Guru G

Publication Date: 2018

Variant appearance in text: PIK3CA: L702H

PubMed Link: 29578115

Variant Present in the following documents:

• Main text
• AJA-20-230.pdf

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Concordance of Circulating Tumor DNA and Matched Metastatic Tissue Biopsy in Prostate Cancer.

Journal Of The National Cancer Institute

Wyatt, Alexander W AW; Annala, Matti M; Aggarwal, Rahul R; Beja, Kevin K; Feng, Felix F; Youngren, Jack J; Foye, Adam A; Lloyd, Paul P; Nykter, Matti M; Beer, Tomasz M TM; Alumkal, Joshi J JJ; Thomas, George V GV; Reiter, Robert E RE; Rettig, Matthew B MB; Evans, Christopher P CP; Gao, Allen C AC; Chi, Kim N KN; Small, Eric J EJ; Gleave, Martin E ME

Publication Date: 2017-12-01

Variant appearance in text: PI3K: L702H

PubMed Link: 29206995

Variant Present in the following documents:

• Main text

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Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients.

Nature Medicine

Zehir, Ahmet A; Benayed, Ryma R; Shah, Ronak H RH; Syed, Aijazuddin A; Middha, Sumit S; Kim, Hyunjae R HR; Srinivasan, Preethi P; Gao, Jianjiong J; Chakravarty, Debyani D; Devlin, Sean M SM; Hellmann, Matthew D MD; Barron, David A DA; Schram, Alison M AM; Hameed, Meera M; Dogan, Snjezana S; Ross, Dara S DS; Hechtman, Jaclyn F JF; DeLair, Deborah F DF; Yao, JinJuan J; Mandelker, Diana L DL; Cheng, Donavan T DT; Chandramohan, Raghu R; Mohanty, Abhinita S AS; Ptashkin, Ryan N RN; Jayakumaran, Gowtham G; Prasad, Meera M; Syed, Mustafa H MH; Rema, Anoop Balakrishnan AB; Liu, Zhen Y ZY; Nafa, Khedoudja K; Borsu, Laetitia L; Sadowska, Justyna J; Casanova, Jacklyn J; Bacares, Ruben R; Kiecka, Iwona J IJ; Razumova, Anna A; Son, Julie B JB; Stewart, Lisa L; Baldi, Tessara T; Mullaney, Kerry A KA; Al-Ahmadie, Hikmat H; Vakiani, Efsevia E; Abeshouse, Adam A AA; Penson, Alexander V AV; Jonsson, Philip P; Camacho, Niedzica N; Chang, Matthew T MT; Won, Helen H HH; Gross, Benjamin E BE; Kundra, Ritika R; Heins, Zachary J ZJ; Chen, Hsiao-Wei HW; Phillips, Sarah S; Zhang, Hongxin H; Wang, Jiaojiao J; Ochoa, Angelica A; Wills, Jonathan J; Eubank, Michael M; Thomas, Stacy B SB; Gardos, Stuart M SM; Reales, Dalicia N DN; Galle, Jesse J; Durany, Robert R; Cambria, Roy R; Abida, Wassim W; Cercek, Andrea A; Feldman, Darren R DR; Gounder, Mrinal M MM; Hakimi, A Ari AA; Harding, James J JJ; Iyer, Gopa G; Janjigian, Yelena Y YY; Jordan, Emmet J EJ; Kelly, Ciara M CM; Lowery, Maeve A MA; Morris, Luc G T LGT; Omuro, Antonio M AM; Raj, Nitya N; Razavi, Pedram P; Shoushtari, Alexander N AN; Shukla, Neerav N; Soumerai, Tara E TE; Varghese, Anna M AM; Yaeger, Rona R; Coleman, Jonathan J; Bochner, Bernard B; Riely, Gregory J GJ; Saltz, Leonard B LB; Scher, Howard I HI; Sabbatini, Paul J PJ; Robson, Mark E ME; Klimstra, David S DS; Taylor, Barry S BS; Baselga, Jose J; Schultz, Nikolaus N; Hyman, David M DM; Arcila, Maria E ME; Solit, David B DB; Ladanyi, Marc M; Berger, Michael F MF

Publication Date: 2017-06

Variant appearance in text: PIK3CA: L702H

PubMed Link: 28481359

Variant Present in the following documents:

• Main text
• nihms865784.pdf

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Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden.

Genome Medicine

Chalmers, Zachary R ZR; Connelly, Caitlin F CF; Fabrizio, David D; Gay, Laurie L; Ali, Siraj M SM; Ennis, Riley R; Schrock, Alexa A; Campbell, Brittany B; Shlien, Adam A; Chmielecki, Juliann J; Huang, Franklin F; He, Yuting Y; Sun, James J; Tabori, Uri U; Kennedy, Mark M; Lieber, Daniel S DS; Roels, Steven S; White, Jared J; Otto, Geoffrey A GA; Ross, Jeffrey S JS; Garraway, Levi L; Miller, Vincent A VA; Stephens, Phillip J PJ; Frampton, Garrett M GM

Publication Date: 2017-04-19

Variant appearance in text: PIK3CA: L702H

PubMed Link: 28420421

Variant Present in the following documents:

• 13073_2017_424_MOESM7_ESM.xlsx, sheet 1

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Detection fidelity of AR mutations in plasma derived cell-free DNA.

Oncotarget

Goldstein, Alexa A; Toro, Patricia Valda PV; Lee, Justin J; Silberstein, John L JL; Nakazawa, Mary M; Waters, Ian I; Cravero, Karen K; Chu, David D; Cochran, Rory L RL; Kim, Minsoo M; Shinn, Daniel D; Torquato, Samantha S; Hughes, Robert M RM; Pallavajjala, Aparna A; Carducci, Michael A MA; Paller, Channing J CJ; Denmeade, Samuel R SR; Kressel, Bruce B; Trock, Bruce J BJ; Eisenberger, Mario A MA; Antonarakis, Emmanuel S ES; Park, Ben H BH; Hurley, Paula J PJ

Publication Date: 2017-02-28

Variant appearance in text: PIK3CA: L702H

PubMed Link: 28152506

Variant Present in the following documents:

• oncotarget-08-15651.pdf

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Molecular mechanisms underlying resistance to androgen deprivation therapy in prostate cancer.

Oncotarget

Wadosky, Kristine M KM; Koochekpour, Shahriar S

Publication Date: 2016-09-27

Variant appearance in text: PI3K: L702H

PubMed Link: 27487144

Variant Present in the following documents:

• Main text
• oncotarget-07-64447.pdf

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A Pilot Study of Clinical Targeted Next Generation Sequencing for Prostate Cancer: Consequences for Treatment and Genetic Counseling.

The Prostate

Cheng, Heather H HH; Klemfuss, Nola N; Montgomery, Bruce B; Higano, Celestia S CS; Schweizer, Michael T MT; Mostaghel, Elahe A EA; McFerrin, Lisa G LG; Yu, Evan Y EY; Nelson, Peter S PS; Pritchard, Colin C CC

Publication Date: 2016-10

Variant appearance in text: PI3K: L702H

PubMed Link: 27324988

Variant Present in the following documents:

• Main text

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