Publications:

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Recognition of BRAF by CDC37 and Re-Evaluation of the Activation Mechanism for the Class 2 BRAF-L597R Mutant.

Biomolecules

Bjorklund, Dennis M DM; Morgan, R Marc L RML; Oberoi, Jasmeen J; Day, Katie L I M KLIM; Galliou, Panagiota A PA; Prodromou, Chrisostomos C

Publication Date: 2022-06-28

Variant appearance in text: PI3K: L834R

PubMed Link: 35883461

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• biomolecules-12-00905.pdf

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Advances of Targeted Therapy for Hepatocellular Carcinoma.

Frontiers In Oncology

Niu, Mengke M; Yi, Ming M; Li, Ning N; Wu, Kongju K; Wu, Kongming K

Publication Date: 2021

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PubMed Link: 34381735

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• fonc-11-719896.pdf

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Deep mutational analysis reveals functional trade-offs in the sequences of EGFR autophosphorylation sites.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Cantor, Aaron J AJ; Shah, Neel H NH; Kuriyan, John J

Publication Date: 2018-07-31

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PubMed Link: 30012625

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• Main text
• pnas.201803598.pdf

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Activation of the EGF Receptor by Ligand Binding and Oncogenic Mutations: The "Rotation Model".

Cells

Purba, Endang R ER; Saita, Ei-Ichiro EI; Maruyama, Ichiro N IN

Publication Date: 2017-06-02

Variant appearance in text: PI3K: L834R

PubMed Link: 28574446

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• Main text
• cells-06-00013.pdf

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Applications of hydrogen/deuterium exchange MS from 2012 to 2014.

Analytical Chemistry

Pirrone, Gregory F GF; Iacob, Roxana E RE; Engen, John R JR

Publication Date: 2015-01-06

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PubMed Link: 25398026

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• Main text
• ac5040242.pdf

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Cellular functions regulated by phosphorylation of EGFR on Tyr845.

International Journal Of Molecular Sciences

Sato, Ken-Ichi K

Publication Date: 2013-05-23

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PubMed Link: 23702846

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• ijms-14-10761.pdf

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Structural systems biology and multiscale signaling models.

Annals Of Biomedical Engineering

Telesco, Shannon E SE; Radhakrishnan, Ravi R

Publication Date: 2012-11

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PubMed Link: 22539148

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Analysis of Somatic Mutations in Cancer: Molecular Mechanisms of Activation in the ErbB Family of Receptor Tyrosine Kinases.

Cancers

Shih, Andrew J AJ; Telesco, Shannon E SE; Radhakrishnan, Ravi R

Publication Date: 2011-03

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PubMed Link: 21701703

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• Main text
• cancers-03-01195.pdf

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Molecular systems biology of ErbB1 signaling: bridging the gap through multiscale modeling and high-performance computing.

Molecular Biosystems

Shih, Andrew J AJ; Purvis, Jeremy J; Radhakrishnan, Ravi R

Publication Date: 2008-12

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PubMed Link: 19396377

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Role of network branching in eliciting differential short-term signaling responses in the hypersensitive epidermal growth factor receptor mutants implicated in lung cancer.

Biotechnology Progress

Purvis, Jeremy J; Ilango, Vibitha V; Radhakrishnan, Ravi R

Publication Date: 2008

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PubMed Link: 18412405

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A multiscale computational approach to dissect early events in the Erb family receptor mediated activation, differential signaling, and relevance to oncogenic transformations.

Annals Of Biomedical Engineering

Liu, Yingting Y; Purvis, Jeremy J; Shih, Andrew A; Weinstein, Joshua J; Agrawal, Neeraj N; Radhakrishnan, Ravi R

Publication Date: 2007-06

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PubMed Link: 17273938

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