PIK3CA c.3062A>T ;(p.Y1021F)

Variant ID: 3-178952007-A-T

NM_006218.2(PIK3CA):c.3062A>T;(p.Y1021F)

This variant was identified in 8 publications

View GRCh38 version.




Publications:


White blood cell and cell-free DNA analyses for detection of residual disease in gastric cancer.

Nature Communications
Leal, Alessandro A; van Grieken, Nicole C T NCT; Palsgrove, Doreen N DN; Phallen, Jillian J; Medina, Jamie E JE; Hruban, Carolyn C; Broeckaert, Mark A M MAM; Anagnostou, Valsamo V; Adleff, Vilmos V; Bruhm, Daniel C DC; Canzoniero, Jenna V JV; Fiksel, Jacob J; Nordsmark, Marianne M; Warmerdam, Fabienne A R M FARM; Verheul, Henk M W HMW; van Spronsen, Dick Johan DJ; Beerepoot, Laurens V LV; Geenen, Maud M MM; Portielje, Johanneke E A JEA; Jansen, Edwin P M EPM; van Sandick, Johanna J; Meershoek-Klein Kranenbarg, Elma E; van Laarhoven, Hanneke W M HWM; van der Peet, Donald L DL; van de Velde, Cornelis J H CJH; Verheij, Marcel M; Fijneman, Remond R; Scharpf, Robert B RB; Meijer, Gerrit A GA; Cats, Annemieke A; Velculescu, Victor E VE
Publication Date: 2020-01-27

Variant appearance in text: PIK3CA: Y1021F
PubMed Link: 31988276
Variant Present in the following documents:
  • 41467_2020_14310_MOESM6_ESM.xlsx, sheet 9
  • 41467_2020_14310_MOESM8_ESM.xlsx, sheet 1
  • 41467_2020_14310_MOESM11_ESM.xlsx, sheet 1
  • 41467_2020_14310_MOESM6_ESM.xlsx, sheet 6
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Mutation status and prognostic values of KRAS, NRAS, BRAF and PIK3CA in 353 Chinese colorectal cancer patients.

Scientific Reports
Guo, Fang F; Gong, Hai H; Zhao, Huanhuan H; Chen, Jing J; Zhang, Yiming Y; Zhang, Lihua L; Shi, Xin X; Zhang, Aifeng A; Jin, Hui H; Zhang, Jianqiong J; He, Youji Y
Publication Date: 2018-04-17

Variant appearance in text: PIK3CA: Y1021F
PubMed Link: 29666387
Variant Present in the following documents:
  • Main text
  • 41598_2018_Article_24306.pdf
View BVdb publication page



Epstein-Barr virus-associated gastric cancer reveals intratumoral heterogeneity of PIK3CA mutations.

Annals Of Oncology : Official Journal Of The European Society For Medical Oncology
Böger, C C; Krüger, S S; Behrens, H M HM; Bock, S S; Haag, J J; Kalthoff, H H; Röcken, C C
Publication Date: 2017-05-01

Variant appearance in text: PIK3CA: Y1021F
PubMed Link: 28453696
Variant Present in the following documents:
  • Main text
  • mdx047.pdf
View BVdb publication page



Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations.

Genome Research
Brammeld, Jonathan S JS; Petljak, Mia M; Martincorena, Inigo I; Williams, Steven P SP; Alonso, Luz Garcia LG; Dalmases, Alba A; Bellosillo, Beatriz B; Robles-Espinoza, Carla Daniela CD; Price, Stacey S; Barthorpe, Syd S; Tarpey, Patrick P; Alifrangis, Constantine C; Bignell, Graham G; Vidal, Joana J; Young, Jamie J; Stebbings, Lucy L; Beal, Kathryn K; Stratton, Michael R MR; Saez-Rodriguez, Julio J; Garnett, Mathew M; Montagut, Clara C; Iorio, Francesco F; McDermott, Ultan U
Publication Date: 2017-04

Variant appearance in text: PIK3CA: 3062A>T; Y1021F
PubMed Link: 28179366
Variant Present in the following documents:
  • supp_gr.213546.116_Supplemental_Table_S7.xlsx, sheet 1
View BVdb publication page



BRAF V600E mutation and KRAS codon 13 mutations predict poor survival in Chinese colorectal cancer patients.

Bmc Cancer
Chen, Jing J; Guo, Fang F; Shi, Xin X; Zhang, Lihua L; Zhang, Aifeng A; Jin, Hui H; He, Youji Y
Publication Date: 2014-11-03

Variant appearance in text: PIK3CA: Y1021F
PubMed Link: 25367198
Variant Present in the following documents:
  • Main text
  • 12885_2014_Article_4999.pdf
View BVdb publication page



Validation and utilisation of high-coverage next-generation sequencing to deliver the pharmacological audit trail.

British Journal Of Cancer
Ong, M M; Carreira, S S; Goodall, J J; Mateo, J J; Figueiredo, I I; Rodrigues, D N DN; Perkins, G G; Seed, G G; Yap, T A TA; Attard, G G; de Bono, J S JS
Publication Date: 2014-08-26

Variant appearance in text: PIK3CA: Y1021F
PubMed Link: 24983367
Variant Present in the following documents:
  • Main text
  • bjc2014350a.pdf
View BVdb publication page



Phosphatidylinositol-3-kinase α catalytic subunit gene somatic mutations in bronchopulmonary neuroendocrine tumours.

Oncology Reports
Capodanno, Alessandra A; Boldrini, Laura L; Alì, Greta G; Pelliccioni, Serena S; Mussi, Alfredo A; Fontanini, Gabriella G
Publication Date: 2012-11

Variant appearance in text: PIK3CA: 3062A>T
PubMed Link: 22949056
Variant Present in the following documents:
  • Main text
  • or-28-05-1559.pdf
View BVdb publication page



Kinase domain mutants of Bcr-Abl exhibit altered transformation potency, kinase activity, and substrate utilization, irrespective of sensitivity to imatinib.

Molecular And Cellular Biology
Griswold, Ian J IJ; MacPartlin, Mary M; Bumm, Thomas T; Goss, Valerie L VL; O'Hare, Thomas T; Lee, Kimberly A KA; Corbin, Amie S AS; Stoffregen, Eric P EP; Smith, Caitlyn C; Johnson, Kara K; Moseson, Erika M EM; Wood, Lisa J LJ; Polakiewicz, Roberto D RD; Druker, Brian J BJ; Deininger, Michael W MW
Publication Date: 2006-08

Variant appearance in text: PI3K: Y1021F
PubMed Link: 16880519
Variant Present in the following documents:
  • Main text
View BVdb publication page