PIK3CA c.3074C>A ;(p.T1025N)

Variant ID: 3-178952019-C-A

NM_006218.2(PIK3CA):c.3074C>A;(p.T1025N)

This variant was identified in 10 publications

View GRCh38 version.




Publications:


Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer
Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA
Publication Date: 2021-05

Variant appearance in text: PIK3CA: 3074C>A; T1025N
PubMed Link: 33704917
Variant Present in the following documents:
  • TCA-12-1271-s003.xls, sheet 1
View BVdb publication page



Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology
Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR
Publication Date: 2019-04

Variant appearance in text: PIK3CA: T1025N
PubMed Link: 31034466
Variant Present in the following documents:
  • pcbi.1006981.s010.xlsx, sheet 1
View BVdb publication page



Use of nonsteroidal anti-inflammatory drugs predicts improved patient survival for PIK3CA-altered head and neck cancer.

The Journal Of Experimental Medicine
Hedberg, Matthew L ML; Peyser, Noah D ND; Bauman, Julie E JE; Gooding, William E WE; Li, Hua H; Bhola, Neil E NE; Zhu, Tian Ran TR; Zeng, Yan Y; Brand, Toni M TM; Kim, Mi-Ok MO; Jordan, Richard C K RCK; VandenBerg, Scott S; Olivas, Victor V; Bivona, Trever G TG; Chiosea, Simion I SI; Wang, Lin L; Mills, Gordon B GB; Johnson, Jonas T JT; Duvvuri, Umamaheswar U; Ferris, Robert L RL; Ha, Patrick P; Johnson, Daniel E DE; Grandis, Jennifer R JR
Publication Date: 2019-02-04

Variant appearance in text: PIK3CA: T1025N
PubMed Link: 30683736
Variant Present in the following documents:
  • Main text
  • JEM_20181936.pdf
View BVdb publication page



Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications
Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ
Publication Date: 2017-05-11

Variant appearance in text: PI3K: 3074C>A
PubMed Link: 28492226
Variant Present in the following documents:
  • ncomms15086-s3.xlsx, sheet 1
View BVdb publication page



Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations.

Genome Research
Brammeld, Jonathan S JS; Petljak, Mia M; Martincorena, Inigo I; Williams, Steven P SP; Alonso, Luz Garcia LG; Dalmases, Alba A; Bellosillo, Beatriz B; Robles-Espinoza, Carla Daniela CD; Price, Stacey S; Barthorpe, Syd S; Tarpey, Patrick P; Alifrangis, Constantine C; Bignell, Graham G; Vidal, Joana J; Young, Jamie J; Stebbings, Lucy L; Beal, Kathryn K; Stratton, Michael R MR; Saez-Rodriguez, Julio J; Garnett, Mathew M; Montagut, Clara C; Iorio, Francesco F; McDermott, Ultan U
Publication Date: 2017-04

Variant appearance in text: PIK3CA: 3074C>A; T1025N
PubMed Link: 28179366
Variant Present in the following documents:
  • supp_gr.213546.116_Supplemental_Table_S7.xlsx, sheet 1
View BVdb publication page



Reproducible Analysis of Post-Translational Modifications in Proteomes--Application to Human Mutations.

Plos One
Holehouse, Alex S AS; Naegle, Kristen M KM
Publication Date: 2015

Variant appearance in text: PI3K: T1025N
PubMed Link: 26659599
Variant Present in the following documents:
  • pone.0144692.s002.xlsx, sheet 1
View BVdb publication page



Lavage of the Uterine Cavity for Molecular Detection of Müllerian Duct Carcinomas: A Proof-of-Concept Study.

Journal Of Clinical Oncology : Official Journal Of The American Society Of Clinical Oncology
Maritschnegg, Elisabeth E; Wang, Yuxuan Y; Pecha, Nina N; Horvat, Reinhard R; Van Nieuwenhuysen, Els E; Vergote, Ignace I; Heitz, Florian F; Sehouli, Jalid J; Kinde, Isaac I; Diaz, Luis A LA; Papadopoulos, Nickolas N; Kinzler, Kenneth W KW; Vogelstein, Bert B; Speiser, Paul P; Zeillinger, Robert R
Publication Date: 2015-12-20

Variant appearance in text: PIK3CA: T1025N
PubMed Link: 26552420
Variant Present in the following documents:
  • Main text
  • zlj4293.pdf
View BVdb publication page



GESPA: classifying nsSNPs to predict disease association.

Bmc Bioinformatics
Khurana, Jay K JK; Reeder, Jay E JE; Shrimpton, Antony E AE; Thakar, Juilee J
Publication Date: 2015-07-25

Variant appearance in text: PIK3CA: T1025N
PubMed Link: 26206375
Variant Present in the following documents:
  • 12859_2015_673_MOESM1_ESM.xls, sheet 2
View BVdb publication page



Predicting the functional impact of protein mutations: application to cancer genomics.

Nucleic Acids Research
Reva, Boris B; Antipin, Yevgeniy Y; Sander, Chris C
Publication Date: 2011-09-01

Variant appearance in text: PIK3CA: T1025N
PubMed Link: 21727090
Variant Present in the following documents:
  • supp_gkr407_Supplement2_Table_SM1_COSMIC_mutations.xls, sheet 1
View BVdb publication page



A unique spectrum of somatic PIK3CA (p110alpha) mutations within primary endometrial carcinomas.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Rudd, Meghan L ML; Price, Jessica C JC; Fogoros, Sarah S; Godwin, Andrew K AK; Sgroi, Dennis C DC; Merino, Maria J MJ; Bell, Daphne W DW
Publication Date: 2011-03-15

Variant appearance in text: PIK3CA: T1025N
PubMed Link: 21266528
Variant Present in the following documents:
  • Main text
View BVdb publication page