Publications:

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Genomic landscape, immune characteristics and prognostic mutation signature of cervical cancer in China.

Bmc Medical Genomics

Liu, Jing J; Li, Zirong Z; Lu, Ting T; Pan, Junping J; Li, Li L; Song, Yanwen Y; Hu, Dan D; Zhuo, Yanhong Y; Chen, Ying Y; Xu, Qin Q

Publication Date: 2022-11-04

Variant appearance in text: PIK3CA: 3136G>A; A1046T

PubMed Link: 36333792

Variant Present in the following documents:

• 12920_2022_1376_MOESM1_ESM.xlsx, sheet 1

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Duplex Sequencing Uncovers Recurrent Low-frequency Cancer-associated Mutations in Infant and Childhood KMT2A-rearranged Acute Leukemia.

Hemasphere

Pilheden, Mattias M; Ahlgren, Louise L; Hyrenius-Wittsten, Axel A; Gonzalez-Pena, Veronica V; Sturesson, Helena H; Hansen Marquart, Hanne Vibeke HV; Lausen, Birgitte B; Castor, Anders A; Pronk, Cornelis Jan CJ; Barbany, Gisela G; Pokrovskaja Tamm, Katja K; Fogelstrand, Linda L; Lohi, Olli O; Norén-Nyström, Ulrika U; Asklin, Johanna J; Chen, Yilun Y; Song, Guangchun G; Walsh, Michael M; Ma, Jing J; Zhang, Jinghui J; Saal, Lao H LH; Gawad, Charles C; Hagström-Andersson, Anna K AK

Publication Date: 2022-10

Variant appearance in text: PIK3CA: A1046T

PubMed Link: 36204688

Variant Present in the following documents:

• hs9-6-e785-s001.xlsx, sheet 6

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: PIK3CA: A1046T

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

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Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer

Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA

Publication Date: 2021-05

Variant appearance in text: PIK3CA: 3136G>A; A1046T

PubMed Link: 33704917

Variant Present in the following documents:

• TCA-12-1271-s003.xls, sheet 1

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: PIK3CA: A1046T

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12

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Clinical Implication of Concordant or Discordant Genomic Profiling between Primary and Matched Metastatic Tissues in Patients with Colorectal Cancer.

Cancer Research And Treatment

Choi, Jung Yoon JY; Choi, Sunho S; Lee, Minhyeok M; Park, Young Soo YS; Sung, Jae Sook JS; Chang, Won Jin WJ; Kim, Ju Won JW; Choi, Yoon Ji YJ; Kim, Jin J; Kim, Dong-Sik DS; Lee, Sung-Ho SH; Seok, Junhee J; Park, Kyong Hwa KH; Kim, Seon Hahn SH; Kim, Yeul Hong YH

Publication Date: 2020-07

Variant appearance in text: PIK3CA: A1046T

PubMed Link: 32065847

Variant Present in the following documents:

• crt-2020-044.pdf

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Targeted next-generation sequencing of cancer-related genes in thyroid carcinoma: A single institution's experience.

Oncology Letters

Bandoh, Nobuyuki N; Akahane, Toshiaki T; Goto, Takashi T; Kono, Michihisa M; Ichikawa, Haruyuki H; Sawada, Takahiro T; Yamaguchi, Tomomi T; Nakano, Hiroshi H; Kawase, Yumiko Y; Kato, Yasutaka Y; Kamada, Hajime H; Harabuchi, Yasuaki Y; Shimizu, Kazuo K; Nishihara, Hiroshi H

Publication Date: 2018-12

Variant appearance in text: PIK3CA: A1046T

PubMed Link: 30546467

Variant Present in the following documents:

• Main text

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Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One

Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS

Publication Date: 2018

Variant appearance in text: PIK3CA: A1046T

PubMed Link: 29698444

Variant Present in the following documents:

• pone.0196434.s001.xlsx, sheet 2
• pone.0196434.s001.xlsx, sheet 3
• pone.0196434.s001.xlsx, sheet 1

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Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients.

Nature Communications

Chen, Li L; Yang, Liu L; Yao, Ling L; Kuang, Xia-Ying XY; Zuo, Wen-Jia WJ; Li, Shan S; Qiao, Feng F; Liu, Yi-Rong YR; Cao, Zhi-Gang ZG; Zhou, Shu-Ling SL; Zhou, Xiao-Yan XY; Yang, Wen-Tao WT; Shi, Jin-Xiu JX; Huang, Wei W; Hu, Xin X; Shao, Zhi-Ming ZM

Publication Date: 2018-04-10

Variant appearance in text: PIK3CA: A1046T

PubMed Link: 29636477

Variant Present in the following documents:

• 41467_2018_Article_3867.pdf
• 41467_2018_3867_MOESM1_ESM.pdf

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Pan-urologic cancer genomic subtypes that transcend tissue of origin.

Nature Communications

Chen, Fengju F; Zhang, Yiqun Y; Bossé, Dominick D; Lalani, Aly-Khan A AA; Hakimi, A Ari AA; Hsieh, James J JJ; Choueiri, Toni K TK; Gibbons, Don L DL; Ittmann, Michael M; Creighton, Chad J CJ

Publication Date: 2017-08-04

Variant appearance in text: PIK3CA: 3136G>A; A1046T

PubMed Link: 28775315

Variant Present in the following documents:

• 41467_2017_289_MOESM7_ESM.xlsx, sheet 1

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Molecular profiling of signet ring cell colorectal cancer provides a strong rationale for genomic targeted and immune checkpoint inhibitor therapies.

British Journal Of Cancer

Alvi, Muhammad A MA; Loughrey, Maurice B MB; Dunne, Philip P; McQuaid, Stephen S; Turkington, Richard R; Fuchs, Marc-Aurel MA; McGready, Claire C; Bingham, Victoria V; Pang, Brendan B; Moore, Wendy W; Maxwell, Perry P; Lawler, Mark M; James, Jacqueline A JA; Murray, Graeme I GI; Wilson, Richard H RH; Salto-Tellez, Manuel M

Publication Date: 2017-07-11

Variant appearance in text: PIK3CA: 3136G>A; Ala1046Thr

PubMed Link: 28595259

Variant Present in the following documents:

• bjc2017168x11.xlsx, sheet 1

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Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications

Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ

Publication Date: 2017-05-11

Variant appearance in text: PI3K: 3136G>A

PubMed Link: 28492226

Variant Present in the following documents:

• ncomms15086-s3.xlsx, sheet 1

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Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations.

Genome Research

Brammeld, Jonathan S JS; Petljak, Mia M; Martincorena, Inigo I; Williams, Steven P SP; Alonso, Luz Garcia LG; Dalmases, Alba A; Bellosillo, Beatriz B; Robles-Espinoza, Carla Daniela CD; Price, Stacey S; Barthorpe, Syd S; Tarpey, Patrick P; Alifrangis, Constantine C; Bignell, Graham G; Vidal, Joana J; Young, Jamie J; Stebbings, Lucy L; Beal, Kathryn K; Stratton, Michael R MR; Saez-Rodriguez, Julio J; Garnett, Mathew M; Montagut, Clara C; Iorio, Francesco F; McDermott, Ultan U

Publication Date: 2017-04

Variant appearance in text: PIK3CA: 3136G>A; A1046T

PubMed Link: 28179366

Variant Present in the following documents:

• supp_gr.213546.116_Supplemental_Table_S7.xlsx, sheet 1

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Mutations of KRAS/NRAS/BRAF predict cetuximab resistance in metastatic colorectal cancer patients.

Oncotarget

Hsu, Hung-Chih HC; Thiam, Tan Kien TK; Lu, Yen-Jung YJ; Yeh, Chien Yuh CY; Tsai, Wen-Sy WS; You, Jeng Fu JF; Hung, Hsin Yuan HY; Tsai, Chi-Neu CN; Hsu, An A; Chen, Hua-Chien HC; Chen, Shu-Jen SJ; Yang, Tsai-Sheng TS

Publication Date: 2016-04-19

Variant appearance in text: PIK3CA: 3136G>A; A1046T

PubMed Link: 26989027

Variant Present in the following documents:

• oncotarget-07-22257-s001.pdf

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Rosai-Dorfman Disease Harboring an Activating KRAS K117N Missense Mutation.

Head And Neck Pathology

Shanmugam, Vignesh V; Margolskee, Elizabeth E; Kluk, Michael M; Giorgadze, Tamara T; Orazi, Attilio A

Publication Date: 2016-09

Variant appearance in text: PIK3CA: A1046T

PubMed Link: 26922062

Variant Present in the following documents:

• Main text

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Assessing the clinical value of targeted massively parallel sequencing in a longitudinal, prospective population-based study of cancer patients.

British Journal Of Cancer

Wong, S Q SQ; Fellowes, A A; Doig, K K; Ellul, J J; Bosma, T J TJ; Irwin, D D; Vedururu, R R; Tan, A Y-C AY; Weiss, J J; Chan, K S KS; Lucas, M M; Thomas, D M DM; Dobrovic, A A; Parisot, J P JP; Fox, S B SB

Publication Date: 2015-04-14

Variant appearance in text: PIK3CA: 3136G>A; Ala1046Thr

PubMed Link: 25742471

Variant Present in the following documents:

• bjc201580x7.xls, sheet 1

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Contribution of Beta-HPV Infection and UV Damage to Rapid-Onset Cutaneous Squamous Cell Carcinoma during BRAF-Inhibition Therapy.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Cohen, Daniel N DN; Lawson, Steven K SK; Shaver, Aaron C AC; Du, Liping L; Nguyen, Harrison P HP; He, Qin Q; Johnson, Douglas B DB; Lumbang, Wilfred A WA; Moody, Brent R BR; Prescott, James L JL; Chandra, Pranil K PK; Boyd, Alan S AS; Zwerner, Jeffrey P JP; Robbins, Jason B JB; Tyring, Stephen K SK; Rady, Peter L PL; Chappell, James D JD; Shyr, Yu Y; Infante, Jeffrey R JR; Sosman, Jeffrey A JA

Publication Date: 2015-06-01

Variant appearance in text: PIK3CA: 3136G>A; A1046T

PubMed Link: 25724524

Variant Present in the following documents:

• Main text

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Recurrent RAS and PIK3CA mutations in Erdheim-Chester disease.

Blood

Emile, Jean-François JF; Diamond, Eli L EL; Hélias-Rodzewicz, Zofia Z; Cohen-Aubart, Fleur F; Charlotte, Frédéric F; Hyman, David M DM; Kim, Eunhee E; Rampal, Raajit R; Patel, Minal M; Ganzel, Chezi C; Aumann, Shlomzion S; Faucher, Gladwys G; Le Gall, Catherine C; Leroy, Karen K; Colombat, Magali M; Kahn, Jean-Emmanuel JE; Trad, Salim S; Nizard, Philippe P; Donadieu, Jean J; Taly, Valérie V; Amoura, Zahir Z; Abdel-Wahab, Omar O; Haroche, Julien J

Publication Date: 2014-11-06

Variant appearance in text: PIK3CA: A1046T

PubMed Link: 25150293

Variant Present in the following documents:

• Main text

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Prognostic role of PIK3CA mutation in colorectal cancer: cohort study and literature review.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Liao, Xiaoyun X; Morikawa, Teppei T; Lochhead, Paul P; Imamura, Yu Y; Kuchiba, Aya A; Yamauchi, Mai M; Nosho, Katsuhiko K; Qian, Zhi Rong ZR; Nishihara, Reiko R; Meyerhardt, Jeffrey A JA; Fuchs, Charles S CS; Ogino, Shuji S

Publication Date: 2012-04-15

Variant appearance in text: PIK3CA: 3136G>A

PubMed Link: 22357840

Variant Present in the following documents:

• Main text

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Predicting the functional impact of protein mutations: application to cancer genomics.

Nucleic Acids Research

Reva, Boris B; Antipin, Yevgeniy Y; Sander, Chris C

Publication Date: 2011-09-01

Variant appearance in text: PIK3CA: A1046T

PubMed Link: 21727090

Variant Present in the following documents:

• supp_gkr407_Supplement2_Table_SM1_COSMIC_mutations.xls, sheet 1

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PIK3CA hotspot mutation scanning by a novel and highly sensitive high-resolution small amplicon melting analysis method.

The Journal Of Molecular Diagnostics : Jmd

Vorkas, Panagiotis A PA; Poumpouridou, Nikoleta N; Agelaki, Sophia S; Kroupis, Christos C; Georgoulias, Vassilis V; Lianidou, Evi S ES

Publication Date: 2010-09

Variant appearance in text: PI3K: 3136G>A

PubMed Link: 20616362

Variant Present in the following documents:

• Main text

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PIK3CA mutation in colorectal cancer: relationship with genetic and epigenetic alterations.

Neoplasia (New York, N.Y.)

Nosho, Katsuhiko K; Kawasaki, Takako T; Ohnishi, Mutsuko M; Suemoto, Yuko Y; Kirkner, Gregory J GJ; Zepf, Dimity D; Yan, Liying L; Longtine, Janina A JA; Fuchs, Charles S CS; Ogino, Shuji S

Publication Date: 2008-06

Variant appearance in text: PIK3CA: 3136G>A

PubMed Link: 18516290

Variant Present in the following documents:

• Main text

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