Publications:

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An effective AKT inhibitor-PARP inhibitor combination therapy for recurrent ovarian cancer.

Cancer Chemotherapy And Pharmacology

Xu, Jing J; Gao, Yi Y; Luan, Xiaotian X; Li, Ke K; Wang, Jing J; Dai, Yilin Y; Kang, Mingyi M; Lu, Chong C; Zhang, Minhua M; Lu, Chris X CX; Kang, Yu Y; Xu, Congjian C

Publication Date: 2022-05

Variant appearance in text: PI3K: F1059L

PubMed Link: 35419627

Variant Present in the following documents:

• Main text

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Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One

Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS

Publication Date: 2018

Variant appearance in text: PIK3CA: F1059L

PubMed Link: 29698444

Variant Present in the following documents:

• pone.0196434.s001.xlsx, sheet 1
• pone.0196434.s001.xlsx, sheet 2

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Molecular characterization of circulating colorectal tumor cells defines genetic signatures for individualized cancer care.

Oncotarget

Kong, Say Li SL; Liu, Xingliang X; Suhaimi, Nur-Afidah Mohamed NM; Koh, Kenneth Jia Hao KJH; Hu, Min M; Lee, Daniel Yoke San DYS; Cima, Igor I; Phyo, Wai Min WM; Lee, Esther Xing Wei EXW; Tai, Joyce A JA; Foong, Yu Miin YM; Vo, Jess Honganh JH; Koh, Poh Koon PK; Zhang, Tong T; Ying, Jackie Y JY; Lim, Bing B; Tan, Min-Han MH; Hillmer, Axel M AM

Publication Date: 2017-09-15

Variant appearance in text: PIK3CA: F1059L

PubMed Link: 28978093

Variant Present in the following documents:

• oncotarget-08-68026-s002.xlsx, sheet 3

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Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications

Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ

Publication Date: 2017-05-11

Variant appearance in text: PI3K: 3177C>A

PubMed Link: 28492226

Variant Present in the following documents:

• ncomms15086-s3.xlsx, sheet 1

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ATM mutations and E-cadherin expression define sensitivity to EGFR-targeted therapy in colorectal cancer.

Oncotarget

Geißler, Anna-Lena AL; Geißler, Miriam M; Kottmann, Daniel D; Lutz, Lisa L; Fichter, Christiane D CD; Fritsch, Ralph R; Weddeling, Britta B; Makowiec, Frank F; Werner, Martin M; Lassmann, Silke S

Publication Date: 2017-03-07

Variant appearance in text: PIK3CA: Phe1059Leu

PubMed Link: 28199979

Variant Present in the following documents:

• oncotarget-08-17164-s001.pdf

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Amplicon sequencing of colorectal cancer: variant calling in frozen and formalin-fixed samples.

Plos One

Betge, Johannes J; Kerr, Grainne G; Miersch, Thilo T; Leible, Svenja S; Erdmann, Gerrit G; Galata, Christian L CL; Zhan, Tianzuo T; Gaiser, Timo T; Post, Stefan S; Ebert, Matthias P MP; Horisberger, Karoline K; Boutros, Michael M

Publication Date: 2015

Variant appearance in text: PIK3CA: F1059L

PubMed Link: 26010451

Variant Present in the following documents:

• pone.0127146.s014.xlsx, sheet 3

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Targeting EGFR/HER2 pathways enhances the antiproliferative effect of gemcitabine in biliary tract and gallbladder carcinomas.

Bmc Cancer

Pignochino, Ymera Y; Sarotto, Ivana I; Peraldo-Neia, Caterina C; Penachioni, Junia Y JY; Cavalloni, Giuliana G; Migliardi, Giorgia G; Casorzo, Laura L; Chiorino, Giovanna G; Risio, Mauro M; Bardelli, Alberto A; Aglietta, Massimo M; Leone, Francesco F

Publication Date: 2010-11-18

Variant appearance in text: PI3K: F1059L

PubMed Link: 21087480

Variant Present in the following documents:

• Main text
• 1471-2407-10-631.pdf

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