A likely pathogenic variant putatively affecting splicing of PIGA identified in a multiple congenital anomalies hypotonia-seizures syndrome 2 (MCAHS2) family pedigree via whole-exome sequencing.
Lessons learned from whole exome sequencing in multiplex families affected by a complex genetic disorder, intracranial aneurysm.
Plos One
Farlow, Janice L JL; Lin, Hai H; Sauerbeck, Laura L; Lai, Dongbing D; Koller, Daniel L DL; Pugh, Elizabeth E; Hetrick, Kurt K; Ling, Hua H; Kleinloog, Rachel R; van der Vlies, Pieter P; Deelen, Patrick P; Swertz, Morris A MA; Verweij, Bon H BH; Regli, Luca L; Rinkel, Gabriel J E GJ; Ruigrok, Ynte M YM; Doheny, Kimberly K; Liu, Yunlong Y; Broderick, Joseph J; Foroud, Tatiana T; ,
Integrated analysis of germline and somatic variants in ovarian cancer.
Nature Communications
Kanchi, Krishna L KL; Johnson, Kimberly J KJ; Lu, Charles C; McLellan, Michael D MD; Leiserson, Mark D M MD; Wendl, Michael C MC; Zhang, Qunyuan Q; Koboldt, Daniel C DC; Xie, Mingchao M; Kandoth, Cyriac C; McMichael, Joshua F JF; Wyczalkowski, Matthew A MA; Larson, David E DE; Schmidt, Heather K HK; Miller, Christopher A CA; Fulton, Robert S RS; Spellman, Paul T PT; Mardis, Elaine R ER; Druley, Todd E TE; Graubert, Timothy A TA; Goodfellow, Paul J PJ; Raphael, Benjamin J BJ; Wilson, Richard K RK; Ding, Li L