JAK-STAT signaling in inflammatory breast cancer enables chemotherapy-resistant cell states.
Cancer Research
Stevens, Laura E LE; Peluffo, Guillermo G; Qiu, Xintao X; Temko, Daniel D; Fassl, Anne A; Li, Zheqi Z; Trinh, Anne A; Seehawer, Marco M; Jovanovic, Bojana B; Aleckovic, Masa M; Wilde, Callahan M CM; Geck, Renee C RC; Shu, Shaokun S; Kingston, Natalie L NL; Harper, Nicholas W NW; Almendro, Vanessa V; Pyke, Alanna L AL; Egri, Shawn B SB; Papanastasiou, Malvina M; Clement, Kendell K; Zhou, Ningxuan N; Walker, Sarah S; Salas, Jacqueline J; Park, So Yeon SY; Frank, David A DA; Meissner, Alexander A; Jaffe, Jacob D JD; Sicinski, Piotr P; Toker, Alex A; Michor, Franziska F; Long, Henry W HW; Overmoyer, Beth A BA; Polyak, Kornelia K
Genome-Wide Association Study Data Reveal Genetic Susceptibility to Chronic Inflammatory Intestinal Diseases and Pancreatic Ductal Adenocarcinoma Risk.
Cancer Research
Yuan, Fangcheng F; Hung, Rayjean J RJ; Walsh, Naomi N; Zhang, Han H; Platz, Elizabeth A EA; Wheeler, William W; Song, Lei L; Arslan, Alan A AA; Beane Freeman, Laura E LE; Bracci, Paige P; Canzian, Federico F; Du, Mengmeng M; Gallinger, Steven S; Giles, Graham G GG; Goodman, Phyllis J PJ; Kooperberg, Charles C; Le Marchand, Loic L; Neale, Rachel E RE; Rosendahl, Jonas J; Scelo, Ghislaine G; Shu, Xiao-Ou XO; Visvanathan, Kala K; White, Emily E; Zheng, Wei W; Albanes, Demetrius D; Amiano, Pilar P; Andreotti, Gabriella G; Babic, Ana A; Bamlet, William R WR; Berndt, Sonja I SI; Brennan, Paul P; Bueno-de-Mesquita, Bas B; Buring, Julie E JE; Campbell, Peter T PT; Chanock, Stephen J SJ; Fuchs, Charles S CS; Gaziano, J Michael JM; Goggins, Michael G MG; Hackert, Thilo T; Hartge, Patricia P; Hassan, Manal M MM; Holly, Elizabeth A EA; Hoover, Robert N RN; Katzke, Verena V; Kirsten, Holger H; Kurtz, Robert C RC; Lee, I-Min IM; Malats, Nuria N; Milne, Roger L RL; Murphy, Neil N; Ng, Kimmie K; Oberg, Ann L AL; Porta, Miquel M; Rabe, Kari G KG; Real, Francisco X FX; Rothman, Nathaniel N; Sesso, Howard D HD; Silverman, Debra T DT; Thompson, Ian M IM; Wactawski-Wende, Jean J; Wang, Xiaoliang X; Wentzensen, Nicolas N; Wilkens, Lynne R LR; Yu, Herbert H; Zeleniuch-Jacquotte, Anne A; Shi, Jianxin J; Duell, Eric J EJ; Amundadottir, Laufey T LT; Li, Donghui D; Petersen, Gloria M GM; Wolpin, Brian M BM; Risch, Harvey A HA; Yu, Kai K; Klein, Alison P AP; Stolzenberg-Solomon, Rachael R
Fine-mapping inflammatory bowel disease loci to single-variant resolution.
Nature
Huang, Hailiang H; Fang, Ming M; Jostins, Luke L; Umićević Mirkov, Maša M; Boucher, Gabrielle G; Anderson, Carl A CA; Andersen, Vibeke V; Cleynen, Isabelle I; Cortes, Adrian A; Crins, François F; D'Amato, Mauro M; Deffontaine, Valérie V; Dmitrieva, Julia J; Docampo, Elisa E; Elansary, Mahmoud M; Farh, Kyle Kai-How KK; Franke, Andre A; Gori, Ann-Stephan AS; Goyette, Philippe P; Halfvarson, Jonas J; Haritunians, Talin T; Knight, Jo J; Lawrance, Ian C IC; Lees, Charlie W CW; Louis, Edouard E; Mariman, Rob R; Meuwissen, Theo T; Mni, Myriam M; Momozawa, Yukihide Y; Parkes, Miles M; Spain, Sarah L SL; Théâtre, Emilie E; Trynka, Gosia G; Satsangi, Jack J; van Sommeren, Suzanne S; Vermeire, Severine S; Xavier, Ramnik J RJ; , ; Weersma, Rinse K RK; Duerr, Richard H RH; Mathew, Christopher G CG; Rioux, John D JD; McGovern, Dermot P B DPB; Cho, Judy H JH; Georges, Michel M; Daly, Mark J MJ; Barrett, Jeffrey C JC
Blood and Intestine eQTLs from an Anti-TNF-Resistant Crohn's Disease Cohort Inform IBD Genetic Association Loci.
Clinical And Translational Gastroenterology
Di Narzo, Antonio F AF; Peters, Lauren A LA; Argmann, Carmen C; Stojmirovic, Aleksandar A; Perrigoue, Jacqueline J; Li, Katherine K; Telesco, Shannon S; Kidd, Brian B; Walker, Jennifer J; Dudley, Joel J; Cho, Judy J; Schadt, Eric E EE; Kasarskis, Andrew A; Curran, Mark M; Dobrin, Radu R; Hao, Ke K
Transcriptomic landscape of lncRNAs in inflammatory bowel disease.
Genome Medicine
Mirza, Aashiq H AH; Berthelsen, Claus Hb CH; Seemann, Stefan E SE; Pan, Xiaoyong X; Frederiksen, Klaus S KS; Vilien, Mogens M; Gorodkin, Jan J; Pociot, Flemming F
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.
Nature Genetics
Anderson, Carl A CA; Boucher, Gabrielle G; Lees, Charlie W CW; Franke, Andre A; D'Amato, Mauro M; Taylor, Kent D KD; Lee, James C JC; Goyette, Philippe P; Imielinski, Marcin M; Latiano, Anna A; Lagacé, Caroline C; Scott, Regan R; Amininejad, Leila L; Bumpstead, Suzannah S; Baidoo, Leonard L; Baldassano, Robert N RN; Barclay, Murray M; Bayless, Theodore M TM; Brand, Stephan S; Büning, Carsten C; Colombel, Jean-Frédéric JF; Denson, Lee A LA; De Vos, Martine M; Dubinsky, Marla M; Edwards, Cathryn C; Ellinghaus, David D; Fehrmann, Rudolf S N RS; Floyd, James A B JA; Florin, Timothy T; Franchimont, Denis D; Franke, Lude L; Georges, Michel M; Glas, Jürgen J; Glazer, Nicole L NL; Guthery, Stephen L SL; Haritunians, Talin T; Hayward, Nicholas K NK; Hugot, Jean-Pierre JP; Jobin, Gilles G; Laukens, Debby D; Lawrance, Ian I; Lémann, Marc M; Levine, Arie A; Libioulle, Cecile C; Louis, Edouard E; McGovern, Dermot P DP; Milla, Monica M; Montgomery, Grant W GW; Morley, Katherine I KI; Mowat, Craig C; Ng, Aylwin A; Newman, William W; Ophoff, Roel A RA; Papi, Laura L; Palmieri, Orazio O; Peyrin-Biroulet, Laurent L; Panés, Julián J; Phillips, Anne A; Prescott, Natalie J NJ; Proctor, Deborah D DD; Roberts, Rebecca R; Russell, Richard R; Rutgeerts, Paul P; Sanderson, Jeremy J; Sans, Miquel M; Schumm, Philip P; Seibold, Frank F; Sharma, Yashoda Y; Simms, Lisa A LA; Seielstad, Mark M; Steinhart, A Hillary AH; Targan, Stephan R SR; van den Berg, Leonard H LH; Vatn, Morten M; Verspaget, Hein H; Walters, Thomas T; Wijmenga, Cisca C; Wilson, David C DC; Westra, Harm-Jan HJ; Xavier, Ramnik J RJ; Zhao, Zhen Z ZZ; Ponsioen, Cyriel Y CY; Andersen, Vibeke V; Torkvist, Leif L; Gazouli, Maria M; Anagnou, Nicholas P NP; Karlsen, Tom H TH; Kupcinskas, Limas L; Sventoraityte, Jurgita J; Mansfield, John C JC; Kugathasan, Subra S; Silverberg, Mark S MS; Halfvarson, Jonas J; Rotter, Jerome I JI; Mathew, Christopher G CG; Griffiths, Anne M AM; Gearry, Richard R; Ahmad, Tariq T; Brant, Steven R SR; Chamaillard, Mathias M; Satsangi, Jack J; Cho, Judy H JH; Schreiber, Stefan S; Daly, Mark J MJ; Barrett, Jeffrey C JC; Parkes, Miles M; Annese, Vito V; Hakonarson, Hakon H; Radford-Smith, Graham G; Duerr, Richard H RH; Vermeire, Séverine S; Weersma, Rinse K RK; Rioux, John D JD
Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci.
Proceedings Of The National Academy Of Sciences Of The United States Of America
Raelson, John V JV; Little, Randall D RD; Ruether, Andreas A; Fournier, Hélène H; Paquin, Bruno B; Van Eerdewegh, Paul P; Bradley, W E C WE; Croteau, Pascal P; Nguyen-Huu, Quynh Q; Segal, Jonathan J; Debrus, Sophie S; Allard, René R; Rosenstiel, Philip P; Franke, Andre A; Jacobs, Gunnar G; Nikolaus, Susanna S; Vidal, Jean-Michel JM; Szego, Peter P; Laplante, Nathalie N; Clark, Hilary F HF; Paulussen, René J RJ; Hooper, John W JW; Keith, Tim P TP; Belouchi, Abdelmajid A; Schreiber, Stefan S