Publications:

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How the mechanobiology orchestrates the iterative and reciprocal ECM-cell cross-talk that drives microtissue growth.

Science Advances

Benn, Mario C MC; Pot, Simon A SA; Moeller, Jens J; Yamashita, Tadahiro T; Fonta, Charlotte M CM; Orend, Gertraud G; Kollmannsberger, Philip P; Vogel, Viola V

Publication Date: 2023-03-29

Variant appearance in text: EGF: S13A

PubMed Link: 36989370

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• Main text
• sciadv.add9275.pdf

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CCN3/NOV promotes metastasis and tumor progression via GPNMB-induced EGFR activation in triple-negative breast cancer.

Cell Death & Disease

Son, Seogho S; Kim, Hyungjoo H; Lim, Hogeun H; Lee, Joo-Hyung JH; Lee, Kyung-Min KM; Shin, Incheol I

Publication Date: 2023-02-03

Variant appearance in text: EGF: S13A

PubMed Link: 36737605

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• Main text
• 41419_2023_Article_5608.pdf

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Tyrosine kinase SRC-induced YAP1-KLF5 module regulates cancer stemness and metastasis in triple-negative breast cancer.

Cellular And Molecular Life Sciences : Cmls

Zou, Hailin H; Luo, Juan J; Guo, Yibo Y; Tong, Tongyu T; Liu, Yuchen Y; Chen, Yun Y; Xiao, Yunjun Y; Ye, Liping L; Zhu, Chengming C; Deng, Liang L; Wang, Bo B; Pan, Yihang Y; Li, Peng P

Publication Date: 2023-01-12

Variant appearance in text: EGF: S13A

PubMed Link: 36633714

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• Main text

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Control of immediate early gene expression by CPEB4-repressor complex-mediated mRNA degradation.

Genome Biology

Poetz, Fabian F; Lebedeva, Svetlana S; Schott, Johanna J; Lindner, Doris D; Ohler, Uwe U; Stoecklin, Georg G

Publication Date: 2022-09-12

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PubMed Link: 36096941

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• Main text
• 13059_2022_Article_2760.pdf

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A senescence stress secretome is a hallmark of therapy-related myeloid neoplasm stromal tissue occurring soon after cytotoxic exposure.

Leukemia

Kutyna, Monika M MM; Kok, Chung Hoow CH; Lim, Yoon Y; Tran, Elizabeth Ngoc Hoa ENH; Campbell, David D; Paton, Sharon S; Thompson-Peach, Chloe C; Lim, Kelly K; Cakouros, Dimitrios D; Arthur, Agnes A; Hughes, Timothy T; Kumar, Sharad S; Thomas, Daniel D; Gronthos, Stan S; Hiwase, Devendra K DK

Publication Date: 2022-11

Variant appearance in text: EGF: S13A

PubMed Link: 36038666

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• 41375_2022_Article_1686.pdf

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Systematic evaluation of parameters in RNA bisulfite sequencing data generation and analysis.

Nar Genomics And Bioinformatics

Johnson, Zachary Z; Xu, Xiguang X; Pacholec, Christina C; Xie, Hehuang H

Publication Date: 2022-06

Variant appearance in text: EGF: S13A

PubMed Link: 35669236

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• Main text
• lqac045.pdf

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The Dynamic Range of Acidity: Tracking Rules for the Unidirectional Penetration of Cellular Compartments.

Chembiochem : A European Journal Of Chemical Biology

Assies, Lea L; Mercier, Vincent V; López-Andarias, Javier J; Roux, Aurelien A; Sakai, Naomi N; Matile, Stefan S

Publication Date: 2022-08-03

Variant appearance in text: EGF: S13A

PubMed Link: 35535626

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• CBIC-23-0-s001.pdf

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The mechanism of activation of MEK1 by B-Raf and KSR1.

Cellular And Molecular Life Sciences : Cmls

Maloney, Ryan C RC; Zhang, Mingzhen M; Liu, Yonglan Y; Jang, Hyunbum H; Nussinov, Ruth R

Publication Date: 2022-05-04

Variant appearance in text: EGF: S13a

PubMed Link: 35508574

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• Main text
• 18_2022_Article_4296.pdf

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Isoforms of the orphan nuclear receptor COUP‑TFII differentially modulate pancreatic cancer progression.

International Journal Of Oncology

Polvani, Simone S; Pepe, Sara S; Tempesti, Sara S; Tarocchi, Mirko M; Marroncini, Giada G; Bencini, Lapo L; Ceni, Elisabetta E; Mello, Tommaso T; Picariello, Lucia L; Simeone, Irene I; Grappone, Cecilia C; Dragoni, Gabriele G; Antonuzzo, Lorenzo L; Giommoni, Elisa E; Milani, Stefano S; Galli, Andrea A

Publication Date: 2022-05

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PubMed Link: 35348189

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• Main text

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Long-chain fatty acyl coenzyme A inhibits NME1/2 and regulates cancer metastasis.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Zhang, Shuai S; Nelson, Ornella D OD; Price, Ian R IR; Zhu, Chengliang C; Lu, Xuan X; Fernandez, Irma R IR; Weiss, Robert S RS; Lin, Hening H

Publication Date: 2022-03-15

Variant appearance in text: EGF: S13A

PubMed Link: 35259022

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• pnas.202117013.pdf

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Stable flow-induced expression of KLK10 inhibits endothelial inflammation and atherosclerosis.

Elife

Williams, Darian D; Mahmoud, Marwa M; Liu, Renfa R; Andueza, Aitor A; Kumar, Sandeep S; Kang, Dong-Won DW; Zhang, Jiahui J; Tamargo, Ian I; Villa-Roel, Nicolas N; Baek, Kyung-In KI; Lee, Hwakyoung H; An, Yongjin Y; Zhang, Leran L; Tate, Edward W EW; Bagchi, Pritha P; Pohl, Jan J; Mosnier, Laurent O LO; Diamandis, Eleftherios P EP; Mihara, Koichiro K; Hollenberg, Morley D MD; Dai, Zhifei Z; Jo, Hanjoong H

Publication Date: 2022-01-11

Variant appearance in text: EGF: S13a

PubMed Link: 35014606

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• Main text

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Stable flow-induced expression of KLK10 inhibits endothelial inflammation and atherosclerosis.

Elife

Williams, Darian D; Mahmoud, Marwa M; Liu, Renfa R; Andueza, Aitor A; Kumar, Sandeep S; Kang, Dong-Won DW; Zhang, Jiahui J; Tamargo, Ian I; Villa-Roel, Nicolas N; Baek, Kyung-In KI; Lee, Hwakyoung H; An, Yongjin Y; Zhang, Leran L; Tate, Edward W EW; Bagchi, Pritha P; Pohl, Jan J; Mosnier, Laurent O LO; Diamandis, Eleftherios P EP; Mihara, Koichiro K; Hollenberg, Morley D MD; Dai, Zhifei Z; Jo, Hanjoong H

Publication Date: 2022-01-11

Variant appearance in text: EGF: S13a

PubMed Link: 35014606

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• Main text

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A shared transcriptional code orchestrates temporal patterning of the central nervous system.

Plos Biology

Sagner, Andreas A; Zhang, Isabel I; Watson, Thomas T; Lazaro, Jorge J; Melchionda, Manuela M; Briscoe, James J

Publication Date: 2021-11

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PubMed Link: 34767545

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• Main text
• pbio.3001450.pdf

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A shared transcriptional code orchestrates temporal patterning of the central nervous system.

Plos Biology

Sagner, Andreas A; Zhang, Isabel I; Watson, Thomas T; Lazaro, Jorge J; Melchionda, Manuela M; Briscoe, James J

Publication Date: 2021-11

Variant appearance in text: EGF: S13A

PubMed Link: 34767545

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• Main text
• pbio.3001450.pdf

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Periostin Exon-21 Antibody Neutralization of Triple-Negative Breast Cancer Cell-Derived Periostin Regulates Tumor-Associated Macrophage Polarization and Angiogenesis.

Cancers

Fujikawa, Tatsuya T; Sanada, Fumihiro F; Taniyama, Yoshiaki Y; Shibata, Kana K; Katsuragi, Naruto N; Koibuchi, Nobutaka N; Akazawa, Kaori K; Kanemoto, Yuko Y; Kuroyanagi, Hidehito H; Shimazu, Kenzo K; Rakugi, Hiromi H; Morishita, Ryuichi R

Publication Date: 2021-10-11

Variant appearance in text: EGF: S13A

PubMed Link: 34680221

Variant Present in the following documents:

• Main text
• cancers-13-05072.pdf

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The N6-Methyladenosine-Modified Pseudogene HSPA7 Correlates With the Tumor Microenvironment and Predicts the Response to Immune Checkpoint Therapy in Glioblastoma.

Frontiers In Immunology

Zhao, Rongrong R; Li, Boyan B; Zhang, Shouji S; He, Zheng Z; Pan, Ziwen Z; Guo, Qindong Q; Qiu, Wei W; Qi, Yanhua Y; Zhao, Shulin S; Wang, Shaobo S; Chen, Zihang Z; Zhang, Ping P; Guo, Xing X; Xue, Hao H; Li, Gang G

Publication Date: 2021

Variant appearance in text: EGF: S13A

PubMed Link: 34354698

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• Main text

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Proteome-Wide Profiling of Readers for DNA Modification.

Advanced Science (Weinheim, Baden-Wurttemberg, Germany)

Bai, Lin L; Yang, Guojian G; Qin, Zhaoyu Z; Lyu, Jiacheng J; Wang, Yunzhi Y; Feng, Jinwen J; Liu, Mingwei M; Gong, Tongqing T; Li, Xianju X; Li, Zhengyang Z; Li, Jixi J; Qin, Jun J; Yang, Wenjun W; Ding, Chen C

Publication Date: 2021-10

Variant appearance in text: EGF: S13A

PubMed Link: 34351703

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• Main text

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PFKFB3 Inhibition Sensitizes DNA Crosslinking Chemotherapies by Suppressing Fanconi Anemia Repair.

Cancers

Ninou, Anna Huguet AH; Lehto, Jemina J; Chioureas, Dimitrios D; Stigsdotter, Hannah H; Schelzig, Korbinian K; Åkerlund, Emma E; Gudoityte, Greta G; Joneborg, Ulrika U; Carlson, Joseph J; Jonkers, Jos J; Seashore-Ludlow, Brinton B; Gustafsson, Nina Marie Susanne NMS

Publication Date: 2021-07-18

Variant appearance in text: EGF: S13a

PubMed Link: 34298817

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• Main text
• cancers-13-03604.pdf

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Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer.

Science Translational Medicine

Chrysostomou, Stelios S; Roy, Rajat R; Prischi, Filippo F; Thamlikitkul, Lucksamon L; Chapman, Kathryn L KL; Mufti, Uwais U; Peach, Robert R; Ding, Laifeng L; Hancock, David D; Moore, Christopher C; Molina-Arcas, Miriam M; Mauri, Francesco F; Pinato, David J DJ; Abrahams, Joel M JM; Ottaviani, Silvia S; Castellano, Leandro L; Giamas, Georgios G; Pascoe, Jennifer J; Moonamale, Devmini D; Pirrie, Sarah S; Gaunt, Claire C; Billingham, Lucinda L; Steven, Neil M NM; Cullen, Michael M; Hrouda, David D; Winkler, Mathias M; Post, John J; Cohen, Philip P; Salpeter, Seth J SJ; Bar, Vered V; Zundelevich, Adi A; Golan, Shay S; Leibovici, Dan D; Lara, Romain R; Klug, David R DR; Yaliraki, Sophia N SN; Barahona, Mauricio M; Wang, Yulan Y; Downward, Julian J; Skehel, J Mark JM; Ali, Maruf M U MMU; Seckl, Michael J MJ; Pardo, Olivier E OE

Publication Date: 2021-07-14

Variant appearance in text: EGF: S13A

PubMed Link: 34261798

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• Main text

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PTEN suppresses tumorigenesis by directly dephosphorylating Akt.

Signal Transduction And Targeted Therapy

Bu, Lang L; Wang, Huan H; Pan, Ji-An JA; Chen, Lang L; Xing, Fan F; Wu, Junyu J; Li, Shun S; Guo, Deyin D

Publication Date: 2021-07-12

Variant appearance in text: EGF: S13a

PubMed Link: 34248141

Variant Present in the following documents:

• Main text

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PTEN suppresses tumorigenesis by directly dephosphorylating Akt.

Signal Transduction And Targeted Therapy

Bu, Lang L; Wang, Huan H; Pan, Ji-An JA; Chen, Lang L; Xing, Fan F; Wu, Junyu J; Li, Shun S; Guo, Deyin D

Publication Date: 2021-07-12

Variant appearance in text: EGF: S13a

PubMed Link: 34248141

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• Main text

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Negative correlation of single-cell PAX3:FOXO1 expression with tumorigenicity in rhabdomyosarcoma.

Life Science Alliance

Regina, Carla C; Hamed, Ebrahem E; Andrieux, Geoffroy G; Angenendt, Sina S; Schneider, Michaela M; Ku, Manching M; Follo, Marie M; Wachtel, Marco M; Ke, Eugene E; Kikuchi, Ken K; Henssen, Anton G AG; Schäfer, Beat W BW; Boerries, Melanie M; Wagers, Amy J AJ; Keller, Charles C; Hettmer, Simone S

Publication Date: 2021-09

Variant appearance in text: EGF: S13A

PubMed Link: 34187933

Variant Present in the following documents:

• Main text
• LSA-2020-01002.pdf

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Spatiotemporally confined red light-controlled gene delivery at single-cell resolution using adeno-associated viral vectors.

Science Advances

Hörner, Maximilian M; Jerez-Longres, Carolina C; Hudek, Anna A; Hook, Sebastian S; Yousefi, O Sascha OS; Schamel, Wolfgang W A WWA; Hörner, Cindy C; Zurbriggen, Matias D MD; Ye, Haifeng H; Wagner, Hanna J HJ; Weber, Wilfried W

Publication Date: 2021-06

Variant appearance in text: EGF: S13A

PubMed Link: 34134986

Variant Present in the following documents:

• Main text
• abf0797.pdf

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Spatiotemporally confined red light-controlled gene delivery at single-cell resolution using adeno-associated viral vectors.

Science Advances

Hörner, Maximilian M; Jerez-Longres, Carolina C; Hudek, Anna A; Hook, Sebastian S; Yousefi, O Sascha OS; Schamel, Wolfgang W A WWA; Hörner, Cindy C; Zurbriggen, Matias D MD; Ye, Haifeng H; Wagner, Hanna J HJ; Weber, Wilfried W

Publication Date: 2021-06

Variant appearance in text: EGF: S13A

PubMed Link: 34134986

Variant Present in the following documents:

• Main text
• abf0797.pdf

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TrkA Interacts with and Phosphorylates STAT3 to Enhance Gene Transcription and Promote Breast Cancer Stem Cells in Triple-Negative and HER2-Enriched Breast Cancers.

Cancers

Regua, Angelina T AT; Aguayo, Noah R NR; Jalboush, Sara Abu SA; Doheny, Daniel L DL; Manore, Sara G SG; Zhu, Dongqin D; Wong, Grace L GL; Arrigo, Austin A; Wagner, Calvin J CJ; Yu, Yang Y; Thomas, Alexandra A; Chan, Michael D MD; Ruiz, Jimmy J; Jin, Guangxu G; Strowd, Roy R; Sun, Peiqing P; Lin, Jiayuh J; Lo, Hui-Wen HW

Publication Date: 2021-05-12

Variant appearance in text: EGF: S13A

PubMed Link: 34066153

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• Main text

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Nuclear FGFR1 Regulates Gene Transcription and Promotes Antiestrogen Resistance in ER+ Breast Cancer.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Servetto, Alberto A; Kollipara, Rahul R; Formisano, Luigi L; Lin, Chang-Ching CC; Lee, Kyung-Min KM; Sudhan, Dhivya R DR; Gonzalez-Ericsson, Paula I PI; Chatterjee, Sumanta S; Guerrero-Zotano, Angel A; Mendiratta, Saurabh S; Akamatsu, Hiroaki H; James, Nicholas N; Bianco, Roberto R; Hanker, Ariella B AB; Kittler, Ralf R; Arteaga, Carlos L CL

Publication Date: 2021-08-01

Variant appearance in text: EGF: S13A

PubMed Link: 34011560

Variant Present in the following documents:

• Main text
• 4379.pdf

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Nuclear FGFR1 Regulates Gene Transcription and Promotes Antiestrogen Resistance in ER+ Breast Cancer.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Servetto, Alberto A; Kollipara, Rahul R; Formisano, Luigi L; Lin, Chang-Ching CC; Lee, Kyung-Min KM; Sudhan, Dhivya R DR; Gonzalez-Ericsson, Paula I PI; Chatterjee, Sumanta S; Guerrero-Zotano, Angel A; Mendiratta, Saurabh S; Akamatsu, Hiroaki H; James, Nicholas N; Bianco, Roberto R; Hanker, Ariella B AB; Kittler, Ralf R; Arteaga, Carlos L CL

Publication Date: 2021-08-01

Variant appearance in text: EGF: S13A

PubMed Link: 34011560

Variant Present in the following documents:

• Main text
• 4379.pdf

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Changes in Biomechanical Properties of A375 Cells Due to the Silencing of TMSB4X Expression Are Not Directly Correlated with Alterations in Their Stemness Features.

Cells

Makowiecka, Aleksandra A; Mazurkiewicz, Ewa E; Mrówczyńska, Ewa E; Malek, Natalia N; Battistella, Alice A; Lazzarino, Marco M; Nowak, Dorota D; Mazur, Antonina Joanna AJ

Publication Date: 2021-03-31

Variant appearance in text: EGF: S13A

PubMed Link: 33807338

Variant Present in the following documents:

• Main text
• cells-10-00769.pdf

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Cellular plasticity balances the metabolic and proliferation dynamics of a regenerating liver.

Genome Research

Chembazhi, Ullas V UV; Bangru, Sushant S; Hernaez, Mikel M; Kalsotra, Auinash A

Publication Date: 2021-04

Variant appearance in text: EGF: S13A

PubMed Link: 33649154

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• Main text

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Genome-wide CRISPR-Cas9 screen identified KLF11 as a druggable suppressor for sarcoma cancer stem cells.

Science Advances

Wang, Yicun Y; Wu, Jinhui J; Chen, Hui H; Yang, Yang Y; Xiao, Chengwu C; Yi, Xiaoming X; Shi, Changjie C; Zhong, Ke K; He, Haowei H; Li, Yaoming Y; Wu, Zhenjie Z; Zhou, Guangxin G; Rao, Qiu Q; Wang, Xiaoxia X; Zhou, Xiaodie X; Lomberk, Gwen G; Liu, Bing B; Zhao, Jianning J; Ge, Jingping J; Zhou, Wenquan W; Chu, Xiaoyuan X; Chen, Cheng C; Zhou, Xuhui X; Wang, Linhui L; Guan, Kunliang K; Qu, Le L

Publication Date: 2021-01

Variant appearance in text: EGF: S13A

PubMed Link: 33571129

Variant Present in the following documents:

• Main text
• abe3445.pdf

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Genome-wide CRISPR-Cas9 screen identified KLF11 as a druggable suppressor for sarcoma cancer stem cells.

Science Advances

Wang, Yicun Y; Wu, Jinhui J; Chen, Hui H; Yang, Yang Y; Xiao, Chengwu C; Yi, Xiaoming X; Shi, Changjie C; Zhong, Ke K; He, Haowei H; Li, Yaoming Y; Wu, Zhenjie Z; Zhou, Guangxin G; Rao, Qiu Q; Wang, Xiaoxia X; Zhou, Xiaodie X; Lomberk, Gwen G; Liu, Bing B; Zhao, Jianning J; Ge, Jingping J; Zhou, Wenquan W; Chu, Xiaoyuan X; Chen, Cheng C; Zhou, Xuhui X; Wang, Linhui L; Guan, Kunliang K; Qu, Le L

Publication Date: 2021-01

Variant appearance in text: EGF: S13A

PubMed Link: 33571129

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• Main text
• abe3445.pdf

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Cartilage oligomeric matrix protein is an endogenous β-arrestin-2-selective allosteric modulator of AT1 receptor counteracting vascular injury.

Cell Research

Fu, Yi Y; Huang, Yaqian Y; Yang, Zhao Z; Chen, Yufei Y; Zheng, Jingang J; Mao, Chenfeng C; Li, Zhiqing Z; Liu, Zhixin Z; Yu, Bing B; Li, Tuoyi T; Wang, Meili M; Xu, Chanjuan C; Zhou, Yiwei Y; Zhao, Guizhen G; Jia, Yiting Y; Guo, Wei W; Jia, Xin X; Zhang, Tao T; Li, Li L; Liu, Ziyi Z; Guo, Shengchao S; Ma, Mingliang M; Zhang, Heng H; Liu, Bo B; Du, Junbao J; Wang, Wengong W; Tang, Chaoshu C; Gao, Pei P; Xu, Qingbo Q; Wang, Xian X; Liu, Jianfeng J; Sun, Jinpeng J; Kong, Wei W

Publication Date: 2021-07

Variant appearance in text: EGF: S13a

PubMed Link: 33510386

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• Main text
• 41422_2020_Article_464.pdf

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Cell swelling, softening and invasion in a three-dimensional breast cancer model.

Nature Physics

Han, Yu Long YL; Pegoraro, Adrian F AF; Li, Hui H; Li, Kaifu K; Yuan, Yuan Y; Xu, Guoqiang G; Gu, Zichen Z; Sun, Jiawei J; Hao, Yukun Y; Gupta, Satish Kumar SK; Li, Yiwei Y; Tang, Wenhui W; Tang, Xiao X; Teng, Lianghong L; Fredberg, Jeffrey J JJ; Guo, Ming M

Publication Date: 2020-01

Variant appearance in text: EGF: S13a

PubMed Link: 32905405

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• Main text
• nihms-1539128.pdf

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Marker Identification of the Grade of Dysplasia of Intraductal Papillary Mucinous Neoplasm in Pancreatic Cyst Fluid by Quantitative Proteomic Profiling.

Cancers

Do, Misol M; Kim, Hongbeom H; Shin, Dongyoon D; Park, Joonho J; Kim, Haeryoung H; Han, Youngmin Y; Jang, Jin-Young JY; Kim, Youngsoo Y

Publication Date: 2020-08-23

Variant appearance in text: EGF: S13A

PubMed Link: 32842508

Variant Present in the following documents:

• cancers-12-02383.pdf

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Pyrvinium Pamoate Induces Death of Triple-Negative Breast Cancer Stem-Like Cells and Reduces Metastases through Effects on Lipid Anabolism.

Cancer Research

Dattilo, Rosanna R; Mottini, Carla C; Camera, Emanuela E; Lamolinara, Alessia A; Auslander, Noam N; Doglioni, Ginevra G; Muscolini, Michela M; Tang, Wei W; Planque, Melanie M; Ercolani, Cristiana C; Buglioni, Simonetta S; Manni, Isabella I; Trisciuoglio, Daniela D; Boe, Alessandra A; Grande, Sveva S; Luciani, Anna Maria AM; Iezzi, Manuela M; Ciliberto, Gennaro G; Ambs, Stefan S; De Maria, Ruggero R; Fendt, Sarah-Maria SM; Ruppin, Eytan E; Cardone, Luca L

Publication Date: 2020-10-01

Variant appearance in text: EGF: S13A

PubMed Link: 32718996

Variant Present in the following documents:

• Main text

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PTPN2 Regulates Interactions Between Macrophages and Intestinal Epithelial Cells to Promote Intestinal Barrier Function.

Gastroenterology

Spalinger, Marianne R MR; Sayoc-Becerra, Anica A; Santos, Alina N AN; Shawki, Ali A; Canale, Vinicius V; Krishnan, Moorthy M; Niechcial, Anna A; Obialo, Nicole N; Scharl, Michael M; Li, Jiang J; Nair, Meera G MG; McCole, Declan F DF

Publication Date: 2020-11

Variant appearance in text: EGF: S13A

PubMed Link: 32652144

Variant Present in the following documents:

• Main text

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Computational inference of cancer-specific vulnerabilities in clinical samples.

Genome Biology

Jang, Kiwon K; Park, Min Ji MJ; Park, Jae Soon JS; Hwangbo, Haeun H; Sung, Min Kyung MK; Kim, Sinae S; Jung, Jaeyun J; Lee, Jong Won JW; Ahn, Sei-Hyun SH; Chang, Suhwan S; Choi, Jung Kyoon JK

Publication Date: 2020-06-29

Variant appearance in text: EGF: S13A

PubMed Link: 32600395

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• Main text

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Loss of c-Jun N-terminal Kinase 1 and 2 Function in Liver Epithelial Cells Triggers Biliary Hyperproliferation Resembling Cholangiocarcinoma.

Hepatology Communications

Cubero, Francisco Javier FJ; Mohamed, Mohamed Ramadan MR; Woitok, Marius M MM; Zhao, Gang G; Hatting, Maximilian M; Nevzorova, Yulia A YA; Chen, Chaobo C; Haybaeck, Johannes J; de Bruin, Alain A; Avila, Matias A MA; Boekschoten, Mark V MV; Davis, Roger J RJ; Trautwein, Christian C

Publication Date: 2020-06

Variant appearance in text: EGF: S13A

PubMed Link: 32490320

Variant Present in the following documents:

• HEP4-4-834.pdf

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A salt-induced kinase is required for the metabolic regulation of sleep.

Plos Biology

Grubbs, Jeremy J JJ; Lopes, Lindsey E LE; van der Linden, Alexander M AM; Raizen, David M DM

Publication Date: 2020-04

Variant appearance in text: EGF: S13A

PubMed Link: 32315298

Variant Present in the following documents:

• Main text

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Intein mediated high throughput screening for bispecific antibodies.

Mabs

Hofmann, Tim T; Schmidt, Johannes J; Ciesielski, Elke E; Becker, Stefan S; Rysiok, Thomas T; Schütte, Mark M; Toleikis, Lars L; Kolmar, Harald H; Doerner, Achim A

Publication Date: 2020

Variant appearance in text: EGF: S13A

PubMed Link: 32151188

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Prior acquired resistance to paclitaxel relays diverse EGFR-targeted therapy persistence mechanisms.

Science Advances

Aldonza, Mark Borris D MBD; Ku, Jayoung J; Hong, Ji-Young JY; Kim, Donghwa D; Yu, Seung Jung SJ; Lee, Min-Seok MS; Prayogo, Monica Celine MC; Tan, Stephanie S; Kim, Dayeon D; Han, Jinju J; Lee, Sang Kook SK; Im, Sung Gap SG; Ryu, Han Suk HS; Kim, Yoosik Y

Publication Date: 2020-02

Variant appearance in text: EGF: S13A

PubMed Link: 32083171

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An activator of G protein-coupled receptor and MEK1/2-ERK1/2 signaling inhibits HIV-1 replication by altering viral RNA processing.

Plos Pathogens

Wong, Raymond W RW; Balachandran, Ahalya A; Cheung, Peter K PK; Cheng, Ran R; Pan, Qun Q; Stoilov, Peter P; Harrigan, P Richard PR; Blencowe, Benjamin J BJ; Branch, Donald R DR; Cochrane, Alan A

Publication Date: 2020-02

Variant appearance in text: EGF: S13A

PubMed Link: 32069328

Variant Present in the following documents:

• Main text
• ppat.1008307.pdf

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Complex Rab4-Mediated Regulation of Endosomal Size and EGFR Activation.

Molecular Cancer Research : Mcr

Tubbesing, Kate K; Ward, Jamie J; Abini-Agbomson, Raymond R; Malhotra, Aditi A; Rudkouskaya, Alena A; Warren, Janine J; Lamar, John J; Martino, Nina N; Adam, Alejandro P AP; Barroso, Margarida M

Publication Date: 2020-05

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PubMed Link: 32019812

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Signal flow control of complex signaling networks.

Scientific Reports

Lee, Daewon D; Cho, Kwang-Hyun KH

Publication Date: 2019-10-03

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PubMed Link: 31582789

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Fast-diffusing p75NTR monomers support apoptosis and growth cone collapse by neurotrophin ligands.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Marchetti, Laura L; Bonsignore, Fulvio F; Gobbo, Francesco F; Amodeo, Rosy R; Calvello, Mariantonietta M; Jacob, Ajesh A; Signore, Giovanni G; Schirripa Spagnolo, Chiara C; Porciani, David D; Mainardi, Marco M; Beltram, Fabio F; Luin, Stefano S; Cattaneo, Antonino A

Publication Date: 2019-10-22

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PubMed Link: 31515449

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• pnas.201902790.pdf

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The AMPK-Related Kinases SIK1 and SIK3 Mediate Key Tumor-Suppressive Effects of LKB1 in NSCLC.

Cancer Discovery

Hollstein, Pablo E PE; Eichner, Lillian J LJ; Brun, Sonja N SN; Kamireddy, Anwesh A; Svensson, Robert U RU; Vera, Liliana I LI; Ross, Debbie S DS; Rymoff, T J TJ; Hutchins, Amanda A; Galvez, Hector M HM; Williams, April E AE; Shokhirev, Maxim N MN; Screaton, Robert A RA; Berdeaux, Rebecca R; Shaw, Reuben J RJ

Publication Date: 2019-11

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PubMed Link: 31350328

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Slowly Reducible Genetically Encoded Green Fluorescent Indicator for In Vivo and Ex Vivo Visualization of Hydrogen Peroxide.

International Journal Of Molecular Sciences

Subach, Oksana M OM; Kunitsyna, Tatiana A TA; Mineyeva, Olga A OA; Lazutkin, Alexander A AA; Bezryadnov, Dmitri V DV; Barykina, Natalia V NV; Piatkevich, Kiryl D KD; Ermakova, Yulia G YG; Bilan, Dmitry S DS; Belousov, Vsevolod V VV; Anokhin, Konstantin V KV; Enikolopov, Grigori N GN; Subach, Fedor V FV

Publication Date: 2019-06-27

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PubMed Link: 31252566

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A compact synthetic pathway rewires cancer signaling to therapeutic effector release.

Science (New York, N.Y.)

Chung, Hokyung K HK; Zou, Xinzhi X; Bajar, Bryce T BT; Brand, Veronica R VR; Huo, Yunwen Y; Alcudia, Javier F JF; Ferrell, James E JE; Lin, Michael Z MZ

Publication Date: 2019-05-03

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PubMed Link: 31048459

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Cortical branched actin determines cell cycle progression.

Cell Research

Molinie, Nicolas N; Rubtsova, Svetlana N SN; Fokin, Artem A; Visweshwaran, Sai P SP; Rocques, Nathalie N; Polesskaya, Anna A; Schnitzler, Anne A; Vacher, Sophie S; Denisov, Evgeny V EV; Tashireva, Lubov A LA; Perelmuter, Vladimir M VM; Cherdyntseva, Nadezhda V NV; Bièche, Ivan I; Gautreau, Alexis M AM

Publication Date: 2019-06

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PubMed Link: 30971746

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• 41422_2019_Article_160.pdf

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MERTK mediated novel site Akt phosphorylation alleviates SAV1 suppression.

Nature Communications

Jiang, Yao Y; Zhang, Yanqiong Y; Leung, Janet Y JY; Fan, Cheng C; Popov, Konstantin I KI; Su, Siyuan S; Qian, Jiayi J; Wang, Xiaodong X; Holtzhausen, Alisha A; Ubil, Eric E; Xiang, Yang Y; Davis, Ian I; Dokholyan, Nikolay V NV; Wu, Gang G; Perou, Charles M CM; Kim, William Y WY; Earp, H Shelton HS; Liu, Pengda P

Publication Date: 2019-04-03

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PubMed Link: 30944303

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• 41467_2019_9233_MOESM1_ESM.pdf

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Active Targeting of Cancer Cells by Nanobody Decorated Polypeptide Micelle with Bio-orthogonally Conjugated Drug.

Nano Letters

Costa, Simone A SA; Mozhdehi, Davoud D; Dzuricky, Michael J MJ; Isaacs, Farren J FJ; Brustad, Eric M EM; Chilkoti, Ashutosh A

Publication Date: 2019-01-09

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PubMed Link: 30540482

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Quantitation of class IA PI3Ks in mice reveals p110-free-p85s and isoform-selective subunit associations and recruitment to receptors.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Tsolakos, N N; Durrant, T N TN; Chessa, T T; Suire, S M SM; Oxley, D D; Kulkarni, S S; Downward, J J; Perisic, O O; Williams, R L RL; Stephens, L L; Hawkins, P T PT

Publication Date: 2018-11-27

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PubMed Link: 30442661

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• pnas.201803446.pdf

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Systems modelling of the EGFR-PYK2-c-Met interaction network predicts and prioritizes synergistic drug combinations for triple-negative breast cancer.

Plos Computational Biology

Shin, Sung-Young SY; Müller, Anna-Katharina AK; Verma, Nandini N; Lev, Sima S; Nguyen, Lan K LK

Publication Date: 2018-06

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PubMed Link: 29920512

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• pcbi.1006192.pdf

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Fatty acid synthase mediates EGFR palmitoylation in EGFR mutated non-small cell lung cancer.

Embo Molecular Medicine

Ali, Azhar A; Levantini, Elena E; Teo, Jun Ting JT; Goggi, Julian J; Clohessy, John G JG; Wu, Chan Shuo CS; Chen, Leilei L; Yang, Henry H; Krishnan, Indira I; Kocher, Olivier O; Zhang, Junyan J; Soo, Ross A RA; Bhakoo, Kishore K; Chin, Tan Min TM; Tenen, Daniel G DG

Publication Date: 2018-03

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PubMed Link: 29449326

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• EMMM-10-e8313.pdf
• EMMM-10-e8313-s007.pdf

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In vivo imaging of emerging endocrine cells reveals a requirement for PI3K-regulated motility in pancreatic islet morphogenesis.

Development (Cambridge, England)

Freudenblum, Julia J; Iglesias, José A JA; Hermann, Martin M; Walsen, Tanja T; Wilfinger, Armin A; Meyer, Dirk D; Kimmel, Robin A RA

Publication Date: 2018-02-08

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PubMed Link: 29386244

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Protein profiling identified key chemokines that regulate the maintenance of human pluripotent stem cells.

Scientific Reports

Jiang, Zongmin Z; Li, Yonggang Y; Ji, Xinglai X; Tang, Yiyuli Y; Yu, Haijing H; Ding, Lei L; Yu, Min M; Cui, Qinghua Q; Zhang, Ming M; Ma, Yanping Y; Li, Meizhang M

Publication Date: 2017-11-06

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PubMed Link: 29109449

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