Minimally invasive transplantation of iPSC-derived ALDHhiSSCloVLA4+ neural stem cells effectively improves the phenotype of an amyotrophic lateral sclerosis model.
Human Molecular Genetics
Nizzardo, Monica M; Simone, Chiara C; Rizzo, Federica F; Ruggieri, Margherita M; Salani, Sabrina S; Riboldi, Giulietta G; Faravelli, Irene I; Zanetta, Chiara C; Bresolin, Nereo N; Comi, Giacomo P GP; Corti, Stefania S
Astrocytes from familial and sporadic ALS patients are toxic to motor neurons.
Nature Biotechnology
Haidet-Phillips, Amanda M AM; Hester, Mark E ME; Miranda, Carlos J CJ; Meyer, Kathrin K; Braun, Lyndsey L; Frakes, Ashley A; Song, SungWon S; Likhite, Shibi S; Murtha, Matthew J MJ; Foust, Kevin D KD; Rao, Meghan M; Eagle, Amy A; Kammesheidt, Anja A; Christensen, Ashley A; Mendell, Jerry R JR; Burghes, Arthur H M AH; Kaspar, Brian K BK