EGF c.473A>G ;(p.K158R)

Variant ID: 4-110864555-A-G

NM_001963.4(EGF):c.473A>G;(p.K158R)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


The brain-specific splice variant of the CDC42 GTPase works together with the kinase ACK to downregulate the EGF receptor in promoting neurogenesis.

The Journal Of Biological Chemistry
Endo, Makoto M; Cerione, Richard A RA
Publication Date: 2022-11

Variant appearance in text: EGF: K158R
PubMed Link: 36206843
Variant Present in the following documents:
  • main.pdf
View BVdb publication page



Regulation of Ack1 localization and activity by the amino-terminal SAM domain.

Bmc Biochemistry
Prieto-Echagüe, Victoria V; Gucwa, Azad A; Brown, Deborah A DA; Miller, W Todd WT
Publication Date: 2010-10-27

Variant appearance in text: EGF: K158R
PubMed Link: 20979614
Variant Present in the following documents:
  • Main text
  • 1471-2091-11-42.pdf
View BVdb publication page



Cancer-associated mutations activate the nonreceptor tyrosine kinase Ack1.

The Journal Of Biological Chemistry
Prieto-Echagüe, Victoria V; Gucwa, Azad A; Craddock, Barbara P BP; Brown, Deborah A DA; Miller, W Todd WT
Publication Date: 2010-04-02

Variant appearance in text: EGF: K158R
PubMed Link: 20110370
Variant Present in the following documents:
  • Main text
View BVdb publication page