EGF c.994_995delinsTC ;(p.Q332S)

Variant ID: 4-110880521-CA-TC

NM_001963.4(EGF):c.994_995delinsTC;(p.Q332S)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


A deimmunized bispecific ligand-directed toxin that shows an impressive anti-pancreatic cancer effect in a systemic nude mouse orthotopic model.

Pancreas
Oh, Seunguk S; Todhunter, Deborah A DA; Panoskaltsis-Mortari, Angela A; Buchsbaum, Donald J DJ; Toma, Shoko S; Vallera, Daniel A DA
Publication Date: 2012-07

Variant appearance in text: EGF: Q332S
PubMed Link: 22258068
Variant Present in the following documents:
  • Main text
View BVdb publication page



A novel reduced immunogenicity bispecific targeted toxin simultaneously recognizing human epidermal growth factor and interleukin-4 receptors in a mouse model of metastatic breast carcinoma.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Oh, Seunguk S; Stish, Brad J BJ; Sachdev, Deepali D; Chen, Hua H; Dudek, Arkadiusz Z AZ; Vallera, Daniel A DA
Publication Date: 2009-10-01

Variant appearance in text: EGF: Q332S
PubMed Link: 19789305
Variant Present in the following documents:
  • Main text
View BVdb publication page



Design and modification of EGF4KDEL 7Mut, a novel bispecific ligand-directed toxin, with decreased immunogenicity and potent anti-mesothelioma activity.

British Journal Of Cancer
Stish, B J BJ; Oh, S S; Chen, H H; Dudek, A Z AZ; Kratzke, R A RA; Vallera, D A DA
Publication Date: 2009-10-06

Variant appearance in text: EGF: Q332S
PubMed Link: 19755995
Variant Present in the following documents:
  • Main text
  • 6605297a.pdf
View BVdb publication page