EGF c.1078_1079delinsGC ;(p.C360A)

Variant ID: 4-110882034-TG-GC

NM_001963.4(EGF):c.1078_1079delinsGC;(p.C360A)

This variant was identified in 9 publications

View GRCh38 version.




Publications:


A quantitative analysis of the interplay of environment, neighborhood, and cell state in 3D spheroids.

Molecular Systems Biology
Zanotelli, Vito Rt VR; Leutenegger, Matthias M; Lun, Xiao-Kang XK; Georgi, Fanny F; de Souza, Natalie N; Bodenmiller, Bernd B
Publication Date: 2020-12

Variant appearance in text: EGF: C360A
PubMed Link: 33369114
Variant Present in the following documents:
  • MSB-16-e9798-s004.xlsx, sheet 1
View BVdb publication page



Narrowing the focus: a toolkit to systematically connect oncogenic signaling pathways with cancer phenotypes.

Genes & Cancer
Singleton, Katherine R KR; Wood, Kris C KC
Publication Date: 2016-07

Variant appearance in text: EGF: C360A
PubMed Link: 27738492
Variant Present in the following documents:
  • ganc-07-218.pdf
View BVdb publication page



Caspase-8 tyrosine-380 phosphorylation inhibits CD95 DISC function by preventing procaspase-8 maturation and cycling within the complex.

Oncogene
Powley, I R IR; Hughes, M A MA; Cain, K K; MacFarlane, M M
Publication Date: 2016-10-27

Variant appearance in text: EGF: C360A
PubMed Link: 27109099
Variant Present in the following documents:
  • Main text
View BVdb publication page



Caspase-8 as a regulator of tumor cell motility.

Current Molecular Medicine
Graf, R P RP; Keller, N N; Barbero, S S; Stupack, D D
Publication Date: 2014-02

Variant appearance in text: EGF: C360A
PubMed Link: 24467204
Variant Present in the following documents:
  • Main text
View BVdb publication page



Small-molecule IAP antagonists sensitize cancer cells to TRAIL-induced apoptosis: roles of XIAP and cIAPs.

Molecular Cancer Therapeutics
Finlay, Darren D; Vamos, Mitchell M; González-López, Marcos M; Ardecky, Robert J RJ; Ganji, Santhi Reddy SR; Yuan, Hongbin H; Su, Ying Y; Cooley, Trina R TR; Hauser, Curt T CT; Welsh, Kate K; Reed, John C JC; Cosford, Nicholas D P ND; Vuori, Kristiina K
Publication Date: 2014-01

Variant appearance in text: EGF: C360A
PubMed Link: 24194568
Variant Present in the following documents:
  • Main text
View BVdb publication page



Phosphorylation of caspase-8 (Thr-263) by ribosomal S6 kinase 2 (RSK2) mediates caspase-8 ubiquitination and stability.

The Journal Of Biological Chemistry
Peng, Cong C; Cho, Yong-Yeon YY; Zhu, Feng F; Zhang, Jishuai J; Wen, Weihong W; Xu, Yanming Y; Yao, Ke K; Ma, Wei-Ya WY; Bode, Ann M AM; Dong, Zigang Z
Publication Date: 2011-03-04

Variant appearance in text: EGF: C360A
PubMed Link: 21183680
Variant Present in the following documents:
  • Main text
View BVdb publication page



Rab5 mediates caspase-8-promoted cell motility and metastasis.

Molecular Biology Of The Cell
Torres, Vicente A VA; Mielgo, Ainhoa A; Barbero, Simone S; Hsiao, Ruth R; Wilkins, John A JA; Stupack, Dwayne G DG
Publication Date: 2010-01-15

Variant appearance in text: EGF: C360A
PubMed Link: 19923319
Variant Present in the following documents:
  • zmk369.pdf
View BVdb publication page



Critical role for caspase-8 in epidermal growth factor signaling.

Cancer Research
Finlay, Darren D; Howes, Amy A; Vuori, Kristiina K
Publication Date: 2009-06-15

Variant appearance in text: EGF: C360A
PubMed Link: 19470771
Variant Present in the following documents:
  • Main text
View BVdb publication page



Alix and ALG-2 are involved in tumor necrosis factor receptor 1-induced cell death.

The Journal Of Biological Chemistry
Mahul-Mellier, Anne-Laure AL; Strappazzon, Flavie F; Petiot, Anne A; Chatellard-Causse, Christine C; Torch, Sakina S; Blot, Béatrice B; Freeman, Kimberley K; Kuhn, Loriane L; Garin, Jérome J; Verna, Jean-Marc JM; Fraboulet, Sandrine S; Sadoul, Rémy R
Publication Date: 2008-12-12

Variant appearance in text: EGF: C360A
PubMed Link: 18936101
Variant Present in the following documents:
  • Main text
View BVdb publication page