Publications:

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A pathogen-derived effector modulates host glucose metabolism by arginine GlcNAcylation of HIF-1α protein.

Plos Pathogens

Xu, Chenxi C; Liu, Xing X; Zha, Huangyuan H; Fan, Sijia S; Zhang, Dawei D; Li, Shan S; Xiao, Wuhan W

Publication Date: 2018-08

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PubMed Link: 30125331

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• ppat.1007259.pdf

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Manipulation of neural progenitor fate through the oxygen sensing pathway.

Methods (San Diego, Calif.)

Xie, Yuan Y; Lowry, William E WE

Publication Date: 2018-01-15

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PubMed Link: 28864353

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The mitochondrial calcium uniporter regulates breast cancer progression via HIF-1α.

Embo Molecular Medicine

Tosatto, Anna A; Sommaggio, Roberta R; Kummerow, Carsten C; Bentham, Robert B RB; Blacker, Thomas S TS; Berecz, Tunde T; Duchen, Michael R MR; Rosato, Antonio A; Bogeski, Ivan I; Szabadkai, Gyorgy G; Rizzuto, Rosario R; Mammucari, Cristina C

Publication Date: 2016-05

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PubMed Link: 27138568

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• Main text
• EMMM-8-569.pdf

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Hypoxia/HIF1α induces lapatinib resistance in ERBB2-positive breast cancer cells via regulation of DUSP2.

Oncotarget

Karakashev, Sergey V SV; Reginato, Mauricio J MJ

Publication Date: 2015-02-10

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PubMed Link: 25596742

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• Main text
• oncotarget-06-1967.pdf

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Hypoxia-inducible factor-1α induces ErbB4 signaling in the differentiating mammary gland.

The Journal Of Biological Chemistry

Paatero, Ilkka I; Seagroves, Tiffany N TN; Vaparanta, Katri K; Han, Wen W; Jones, Frank E FE; Johnson, Randall S RS; Elenius, Klaus K

Publication Date: 2014-08-08

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PubMed Link: 24966332

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Hypoxia induces IGFBP3 in esophageal squamous cancer cells through HIF-1α-mediated mRNA transcription and continuous protein synthesis.

Faseb Journal : Official Publication Of The Federation Of American Societies For Experimental Biology

Natsuizaka, Mitsuteru M; Naganuma, Seiji S; Kagawa, Shingo S; Ohashi, Shinya S; Ahmadi, Azal A; Subramanian, Harry H; Chang, Sanders S; Nakagawa, Kei J KJ; Ji, Xinjun X; Liebhaber, Stephen A SA; Klein-Szanto, Andres J AJ; Nakagawa, Hiroshi H

Publication Date: 2012-06

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PubMed Link: 22415309

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Bcl-2 regulates HIF-1alpha protein stabilization in hypoxic melanoma cells via the molecular chaperone HSP90.

Plos One

Trisciuoglio, Daniela D; Gabellini, Chiara C; Desideri, Marianna M; Ziparo, Elio E; Zupi, Gabriella G; Del Bufalo, Donatella D

Publication Date: 2010-07-27

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PubMed Link: 20668552

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• Main text
• pone.0011772.pdf

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Epidermal growth factor receptor regulates MET levels and invasiveness through hypoxia-inducible factor-1alpha in non-small cell lung cancer cells.

Oncogene

Xu, L L; Nilsson, M B MB; Saintigny, P P; Cascone, T T; Herynk, M H MH; Du, Z Z; Nikolinakos, P G PG; Yang, Y Y; Prudkin, L L; Liu, D D; Lee, J J JJ; Johnson, F M FM; Wong, K-K KK; Girard, L L; Gazdar, A F AF; Minna, J D JD; Kurie, J M JM; Wistuba, I I II; Heymach, J V JV

Publication Date: 2010-05-06

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PubMed Link: 20154724

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Hypoxia-associated factor, a novel E3-ubiquitin ligase, binds and ubiquitinates hypoxia-inducible factor 1alpha, leading to its oxygen-independent degradation.

Molecular And Cellular Biology

Koh, Mei Yee MY; Darnay, Bryant G BG; Powis, Garth G

Publication Date: 2008-12

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PubMed Link: 18838541

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Translational up-regulation of the EGFR by tumor hypoxia provides a nonmutational explanation for its overexpression in human cancer.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Franovic, Aleksandra A; Gunaratnam, Lakshman L; Smith, Karlene K; Robert, Isabelle I; Patten, David D; Lee, Stephen S

Publication Date: 2007-08-07

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PubMed Link: 17670948

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