EGF c.1270C>G ;(p.P424A)

Variant ID: 4-110883099-C-G

NM_001963.4(EGF):c.1270C>G;(p.P424A)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


The pro-apoptotic kinase Mst1 and its caspase cleavage products are direct inhibitors of Akt1.

The Embo Journal
Cinar, Bekir B; Fang, Ping-Ke PK; Lutchman, Mohini M; Di Vizio, Dolores D; Adam, Rosalyn M RM; Pavlova, Natalya N; Rubin, Mark A MA; Yelick, Pamela C PC; Freeman, Michael R MR
Publication Date: 2007-10-31

Variant appearance in text: EGF: P424A
PubMed Link: 17932490
Variant Present in the following documents:
  • Main text
View BVdb publication page



Akt binds to and phosphorylates phospholipase C-gamma1 in response to epidermal growth factor.

Molecular Biology Of The Cell
Wang, Yi Y; Wu, Jiliang J; Wang, Zhixiang Z
Publication Date: 2006-05

Variant appearance in text: EGF: P424A
PubMed Link: 16525023
Variant Present in the following documents:
  • Main text
View BVdb publication page



The adaptor protein Tom1L1 is a negative regulator of Src mitogenic signaling induced by growth factors.

Molecular And Cellular Biology
Franco, Mélanie M; Furstoss, Olivia O; Simon, Valérie V; Benistant, Chrsitine C; Hong, Wan Jing WJ; Roche, Serge S
Publication Date: 2006-03

Variant appearance in text: EGF: P424A
PubMed Link: 16479011
Variant Present in the following documents:
  • Main text
View BVdb publication page