EGF c.1688A>C ;(p.D563A)

Variant ID: 4-110890239-A-C

NM_001963.4(EGF):c.1688A>C;(p.D563A)

This variant was identified in 8 publications

View GRCh38 version.




Publications:


Allosteric regulation of epidermal growth factor (EGF) receptor ligand binding by tyrosine kinase inhibitors.

The Journal Of Biological Chemistry
Macdonald-Obermann, Jennifer L JL; Pike, Linda J LJ
Publication Date: 2018-08-31

Variant appearance in text: EGF: D563A
PubMed Link: 29997256
Variant Present in the following documents:
  • Main text
View BVdb publication page



Plasma-Generated OH Radical Production for Analyzing Three-Dimensional Structure in Protein Therapeutics.

Scientific Reports
Minkoff, Benjamin B BB; Blatz, Joshua M JM; Choudhury, Faraz A FA; Benjamin, Daniel D; Shohet, J Leon JL; Sussman, Michael R MR
Publication Date: 2017-10-11

Variant appearance in text: EGF: D563A
PubMed Link: 29021557
Variant Present in the following documents:
  • Main text
  • 41598_2017_Article_13371.pdf
View BVdb publication page



Molecular basis for multimerization in the activation of the epidermal growth factor receptor.

Elife
Huang, Yongjian Y; Bharill, Shashank S; Karandur, Deepti D; Peterson, Sean M SM; Marita, Morgan M; Shi, Xiaojun X; Kaliszewski, Megan J MJ; Smith, Adam W AW; Isacoff, Ehud Y EY; Kuriyan, John J
Publication Date: 2016-03-28

Variant appearance in text: EGF: D563A
PubMed Link: 27017828
Variant Present in the following documents:
  • Main text
  • elife-14107.pdf
View BVdb publication page



Complex relationship between ligand binding and dimerization in the epidermal growth factor receptor.

Cell Reports
Bessman, Nicholas J NJ; Bagchi, Atrish A; Ferguson, Kathryn M KM; Lemmon, Mark A MA
Publication Date: 2014-11-20

Variant appearance in text: EGF: D563A
PubMed Link: 25453753
Variant Present in the following documents:
  • Main text
View BVdb publication page



The tethering arm of the EGF receptor is required for negative cooperativity and signal transduction.

The Journal Of Biological Chemistry
Adak, Sangeeta S; DeAndrade, Diana D; Pike, Linda J LJ
Publication Date: 2011-01-14

Variant appearance in text: EGF: D563A
PubMed Link: 21047778
Variant Present in the following documents:
  • Main text
View BVdb publication page



ErbB2 resembles an autoinhibited invertebrate epidermal growth factor receptor.

Nature
Alvarado, Diego D; Klein, Daryl E DE; Lemmon, Mark A MA
Publication Date: 2009-09-10

Variant appearance in text: EGF: D563A
PubMed Link: 19718021
Variant Present in the following documents:
  • NIHMS133050-supplement-2.pdf
View BVdb publication page



Mutational activation of ErbB family receptor tyrosine kinases: insights into mechanisms of signal transduction and tumorigenesis.

Bioessays : News And Reviews In Molecular, Cellular And Developmental Biology
Riese, David J DJ; Gallo, Richard M RM; Settleman, Jeffrey J
Publication Date: 2007-06

Variant appearance in text: EGF: D563A
PubMed Link: 17508401
Variant Present in the following documents:
  • Main text
View BVdb publication page



On the nature of low- and high-affinity EGF receptors on living cells.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Ozcan, Ferruh F; Klein, Peter P; Lemmon, Mark A MA; Lax, Irit I; Schlessinger, Joseph J
Publication Date: 2006-04-11

Variant appearance in text: EGF: D563A
PubMed Link: 16571657
Variant Present in the following documents:
  • Main text
View BVdb publication page