EGF c.1993G>A ;(p.V665M)

Variant ID: 4-110897331-G-A

NM_001963.4(EGF):c.1993G>A;(p.V665M)

This variant was identified in 8 publications

View GRCh38 version.




Publications:


Association of Polymorphisms of MASP1/3, COLEC10, and COLEC11 Genes with 3MC Syndrome.

International Journal Of Molecular Sciences
Gajek, Gabriela G; Świerzko, Anna S AS; Cedzyński, Maciej M
Publication Date: 2020-07-31

Variant appearance in text: EGF: 1993G>A
PubMed Link: 32751929
Variant Present in the following documents:
  • Main text
  • ijms-21-05483.pdf
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Allosteric regulation of epidermal growth factor (EGF) receptor ligand binding by tyrosine kinase inhibitors.

The Journal Of Biological Chemistry
Macdonald-Obermann, Jennifer L JL; Pike, Linda J LJ
Publication Date: 2018-08-31

Variant appearance in text: EGF: V665M
PubMed Link: 29997256
Variant Present in the following documents:
  • Main text
View BVdb publication page



Activation of the EGF Receptor by Ligand Binding and Oncogenic Mutations: The "Rotation Model".

Cells
Purba, Endang R ER; Saita, Ei-Ichiro EI; Maruyama, Ichiro N IN
Publication Date: 2017-06-02

Variant appearance in text: EGF: V665M
PubMed Link: 28574446
Variant Present in the following documents:
  • Main text
  • cells-06-00013.pdf
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A structural perspective on the regulation of the epidermal growth factor receptor.

Annual Review Of Biochemistry
Kovacs, Erika E; Zorn, Julie Anne JA; Huang, Yongjian Y; Barros, Tiago T; Kuriyan, John J
Publication Date: 2015

Variant appearance in text: EGF: V665M
PubMed Link: 25621509
Variant Present in the following documents:
  • Main text
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The EGFR family: not so prototypical receptor tyrosine kinases.

Cold Spring Harbor Perspectives In Biology
Lemmon, Mark A MA; Schlessinger, Joseph J; Ferguson, Kathryn M KM
Publication Date: 2014-04-01

Variant appearance in text: EGF: V665M
PubMed Link: 24691965
Variant Present in the following documents:
  • Main text
View BVdb publication page



The membrane-proximal intracellular domain of the epidermal growth factor receptor underlies negative cooperativity in ligand binding.

The Journal Of Biological Chemistry
Adak, Sangeeta S; Yang, Katherine S KS; Macdonald-Obermann, Jennifer J; Pike, Linda J LJ
Publication Date: 2011-12-30

Variant appearance in text: EGF: V665M
PubMed Link: 22069315
Variant Present in the following documents:
  • Main text
View BVdb publication page



Convergence between Wnt-β-catenin and EGFR signaling in cancer.

Molecular Cancer
Hu, Tianhui T; Li, Cunxi C
Publication Date: 2010-09-09

Variant appearance in text: EGF: V665M
PubMed Link: 20828404
Variant Present in the following documents:
  • Main text
  • 1476-4598-9-236.pdf
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The juxtamembrane region of the EGF receptor functions as an activation domain.

Molecular Cell
Red Brewer, Monica M; Choi, Sung Hee SH; Alvarado, Diego D; Moravcevic, Katarina K; Pozzi, Ambra A; Lemmon, Mark A MA; Carpenter, Graham G
Publication Date: 2009-06-26

Variant appearance in text: EGF: V665M
PubMed Link: 19560417
Variant Present in the following documents:
  • Main text
View BVdb publication page