Publications:

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Nitrogen Containing Heterocycles as Anticancer Agents: A Medicinal Chemistry Perspective.

Pharmaceuticals (Basel, Switzerland)

Kumar, Adarsh A; Singh, Ankit Kumar AK; Singh, Harshwardhan H; Vijayan, Veena V; Kumar, Deepak D; Naik, Jashwanth J; Thareja, Suresh S; Yadav, Jagat Pal JP; Pathak, Prateek P; Grishina, Maria M; Verma, Amita A; Khalilullah, Habibullah H; Jaremko, Mariusz M; Emwas, Abdul-Hamid AH; Kumar, Pradeep P

Publication Date: 2023-02-14

Variant appearance in text: EGF: L858R

PubMed Link: 37259442

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• Main text
• pharmaceuticals-16-00299.pdf

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Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Nature Communications

Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA

Publication Date: 2023-04-03

Variant appearance in text: EGF: L858R

PubMed Link: 37012232

Variant Present in the following documents:

• 41467_2023_37547_MOESM12_ESM.xlsx, sheet 2

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Transgelin promotes lung cancer progression via activation of cancer-associated fibroblasts with enhanced IL-6 release.

Oncogenesis

Sun, Chanjun C; Zhang, Kaishang K; Ni, Chen C; Wan, Jiajia J; Duan, Xixi X; Lou, Xiaohan X; Yao, Xiaohan X; Li, Xiangnan X; Wang, Ming M; Gu, Zhuoyu Z; Yang, Pengyuan P; Li, Zhenzhen Z; Qin, Zhihai Z

Publication Date: 2023-03-29

Variant appearance in text: EGF: L858R

PubMed Link: 36990991

Variant Present in the following documents:

• 41389_2023_Article_463.pdf

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Proximity proteome mapping reveals PD-L1-dependent pathways disrupted by anti-PD-L1 antibody specifically in EGFR-mutant lung cancer cells.

Cell Communication And Signaling : Ccs

Letian, Anudari A; Lemma, Eyoel Yemanaberhan EY; Cavaliere, Paola P; Dephoure, Noah N; Altorki, Nasser K NK; McGraw, Timothy E TE

Publication Date: 2023-03-13

Variant appearance in text: EGF: L858R

PubMed Link: 36915197

Variant Present in the following documents:

• Main text
• 12964_2023_Article_1084.pdf

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The Role of Proteomics and Phosphoproteomics in the Discovery of Therapeutic Targets and Biomarkers in Acquired EGFR-TKI-Resistant Non-Small Cell Lung Cancer.

International Journal Of Molecular Sciences

Moonmuang, Sutpirat S; Tantraworasin, Apichat A; Orrapin, Santhasiri S; Udomruk, Sasimol S; Chewaskulyong, Busyamas B; Pruksakorn, Dumnoensun D; Chaiyawat, Parunya P

Publication Date: 2023-03-02

Variant appearance in text: EGF: L858R

PubMed Link: 36902280

Variant Present in the following documents:

• Main text

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Epidermal growth factor receptor modulates hepatitis e virus entry in human hepatocytes -HEP-22-1113.

Hepatology (Baltimore, Md.)

Schrader, Jil Alexandra JA; Burkard, Thomas Leon TL; Brüggemann, Yannick Y; Gömer, André A; Meister, Toni Luise TL; Fu, Rebecca Menhua RM; Mehnert, Ann-Kathrin AK; Dao Thi, Viet Loan VL; Behrendt, Patrick P; Durantel, David D; Broering, Ruth R; Vondran, Florian W R FWR; Todt, Daniel D; Kinast, Volker V; Steinmann, Eike E

Publication Date: 2023-02-07

Variant appearance in text: EGF: L858R

PubMed Link: 36745934

Variant Present in the following documents:

• Main text
• hep-77-2104.pdf

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Advancements in Cancer Immunotherapies.

Vaccines

Roy, Ruchi R; Singh, Sunil Kumar SK; Misra, Sweta S

Publication Date: 2022-12-27

Variant appearance in text: EGF: L858R

PubMed Link: 36679904

Variant Present in the following documents:

• vaccines-11-00059.pdf

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miRNome profiling of lung cancer metastases revealed a key role for miRNA-PD-L1 axis in the modulation of chemotherapy response.

Journal Of Hematology & Oncology

Cuttano, Roberto R; Colangelo, Tommaso T; Guarize, Juliana J; Dama, Elisa E; Cocomazzi, Maria Pia MP; Mazzarelli, Francesco F; Melocchi, Valentina V; Palumbo, Orazio O; Marino, Elena E; Belloni, Elena E; Montani, Francesca F; Vecchi, Manuela M; Barberis, Massimo M; Graziano, Paolo P; Pasquier, Andrea A; Sanz-Ortega, Julian J; Montuenga, Luis M LM; Carbonelli, Cristiano C; Spaggiari, Lorenzo L; Bianchi, Fabrizio F

Publication Date: 2022-12-31

Variant appearance in text: EGF: L858R

PubMed Link: 36587234

Variant Present in the following documents:

• Main text
• 13045_2022_Article_1394.pdf

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Luteolin: a flavonoid with a multifaceted anticancer potential.

Cancer Cell International

Prasher, Parteek P; Sharma, Mousmee M; Singh, Sachin Kumar SK; Gulati, Monica M; Chellappan, Dinesh Kumar DK; Zacconi, Flavia F; De Rubis, Gabriele G; Gupta, Gaurav G; Sharifi-Rad, Javad J; Cho, William C WC; Dua, Kamal K

Publication Date: 2022-12-08

Variant appearance in text: EGF: L858R

PubMed Link: 36482329

Variant Present in the following documents:

• Main text
• 12935_2022_Article_2808.pdf

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Targeting the EGF receptor family in non-small cell lung cancer-increased complexity and future perspectives.

Cancer Biology & Medicine

Boch, Tobias T; Köhler, Jens J; Janning, Melanie M; Loges, Sonja S

Publication Date: 2022-12-05

Variant appearance in text: EGF: L858R

PubMed Link: 36476337

Variant Present in the following documents:

• Main text
• cbm-19-1543.pdf

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Polyclonal antibody-induced downregulation of HER1/EGFR and HER2 surpasses the effect of combinations of specific registered antibodies.

Frontiers In Oncology

Bergado-Báez, Gretchen G; Gonzalez Suarez, Narjara N; García, Lisset Chao LC; Pérez-Martínez, Dayana D; Hernández-Fernández, Diana Rosa DR; Fundora-Barrios, Talia T; Rodríguez-Álvarez, Antonio A; Díaz-Ordaz, Geidy Diana GD; Lindzen, Moshit M; Yarden, Yosef Y; Sánchez-Ramírez, Belinda B

Publication Date: 2022

Variant appearance in text: EGF: L858R

PubMed Link: 36408164

Variant Present in the following documents:

• Main text
• fonc-12-951267.pdf

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Discovery of a Novel Potent Antitumor Molecule, P19G1, by Erlotinib Derivative Libraries Synthesized by Modular Click-Chemistry.

Technology In Cancer Research & Treatment

Cui, Qianfei Q; Song, Peng P; Ma, Tiancheng T; Wang, Zefeng Z; Lu, Xiaojing X; Shi, Yongjia Y; Zhang, Fang F; Lin, Guoqiang G; Dong, Jiajia J; Zhang, Jiange J

Publication Date: 2022

Variant appearance in text: EGF: L858R

PubMed Link: 36303409

Variant Present in the following documents:

• 10.1177_15330338221109649.pdf

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Qingfei Jiedu decoction inhibits PD-L1 expression in lung adenocarcinoma based on network pharmacology analysis, molecular docking and experimental verification.

Frontiers In Pharmacology

Pan, Junjie J; Yang, Hongkuan H; Zhu, Lihong L; Lou, Yafang Y; Jin, Bo B

Publication Date: 2022

Variant appearance in text: EGF: L858R

PubMed Link: 36091822

Variant Present in the following documents:

• fphar-13-897966.pdf

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Cartilage Oligomeric Matrix Protein, Diseases, and Therapeutic Opportunities.

International Journal Of Molecular Sciences

Cui, Jiarui J; Zhang, Jiaming J

Publication Date: 2022-08-17

Variant appearance in text: EGF: L858R

PubMed Link: 36012514

Variant Present in the following documents:

• Main text

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Recent Advances Regarding the Molecular Mechanisms of Triterpenic Acids: A Review (Part I).

International Journal Of Molecular Sciences

Mioc, Marius M; Milan, Andreea A; Malița, Daniel D; Mioc, Alexandra A; Prodea, Alexandra A; Racoviceanu, Roxana R; Ghiulai, Roxana R; Cristea, Andreea A; Căruntu, Florina F; Șoica, Codruța C

Publication Date: 2022-07-13

Variant appearance in text: EGF: L858R

PubMed Link: 35887090

Variant Present in the following documents:

• Main text
• ijms-23-07740.pdf

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Drug repositioning of tranilast to sensitize a cancer therapy by targeting cancer-associated fibroblast.

Cancer Science

Ochi, Kosuke K; Suzawa, Ken K; Thu, Yin Min YM; Takatsu, Fumiaki F; Tsudaka, Shimpei S; Zhu, Yidan Y; Nakata, Kentaro K; Takeda, Tatsuaki T; Shien, Kazuhiko K; Yamamoto, Hiromasa H; Okazaki, Mikio M; Sugimoto, Seiichiro S; Shien, Tadahiko T; Okamoto, Yoshiharu Y; Tomida, Shuta S; Toyooka, Shinichi S

Publication Date: 2022-10

Variant appearance in text: EGF: L858R

PubMed Link: 35871750

Variant Present in the following documents:

• Main text

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Small-molecule IKKβ activation modulator (IKAM) targets MAP3K1 and inhibits pancreatic tumor growth.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Napoleon, John Victor JV; Sagar, Satish S; Kubica, Sydney P SP; Boghean, Lidia L; Kour, Smit S; King, Hannah M HM; Sonawane, Yogesh A YA; Crawford, Ayrianne J AJ; Gautam, Nagsen N; Kizhake, Smitha S; Bialk, Pawel A PA; Kmiec, Eric E; Mallareddy, Jayapal Reddy JR; Patil, Prathamesh P PP; Rana, Sandeep S; Singh, Sarbjit S; Prahlad, Janani J; Grandgenett, Paul M PM; Borgstahl, Gloria E O GEO; Ghosal, Gargi G; Alnouti, Yazen Y; Hollingsworth, Michael A MA; Radhakrishnan, Prakash P; Natarajan, Amarnath A

Publication Date: 2022-05-03

Variant appearance in text: EGF: L858R

PubMed Link: 35476515

Variant Present in the following documents:

• pnas.2115071119.sapp.pdf

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Bax/Bcl-2 Cascade Is Regulated by the EGFR Pathway: Therapeutic Targeting of Non-Small Cell Lung Cancer.

Frontiers In Oncology

Alam, Manzar M; Alam, Shoaib S; Shamsi, Anas A; Adnan, Mohd M; Elasbali, Abdelbaset Mohamed AM; Al-Soud, Waleed Abu WA; Alreshidi, Mousa M; Hawsawi, Yousef MohammedRabaa YM; Tippana, Anitha A; Pasupuleti, Visweswara Rao VR; Hassan, Md Imtaiyaz MI

Publication Date: 2022

Variant appearance in text: EGF: L858R

PubMed Link: 35402265

Variant Present in the following documents:

• Main text
• fonc-12-869672.pdf

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Anaplastic thyroid cancer: genome-based search for new targeted therapy options.

Endocrine Connections

Hescheler, Daniel Alexander DA; Hartmann, Milan Janis Michael MJM; Riemann, Burkhard B; Michel, Maximilian M; Bruns, Christiane Josephine CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2022-04-29

Variant appearance in text: EGF: L858R

PubMed Link: 35275096

Variant Present in the following documents:

• supplementary_table_1.xlsx, sheet 1

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Systematic Review of Gossypol/AT-101 in Cancer Clinical Trials.

Pharmaceuticals (Basel, Switzerland)

Renner, Olga O; Mayer, Mascha M; Leischner, Christian C; Burkard, Markus M; Berger, Alexander A; Lauer, Ulrich M UM; Venturelli, Sascha S; Bischoff, Stephan C SC

Publication Date: 2022-01-26

Variant appearance in text: EGF: L858R

PubMed Link: 35215257

Variant Present in the following documents:

• pharmaceuticals-15-00144.pdf

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Clinical utility of cerebrospinal fluid-derived circular RNAs in lung adenocarcinoma patients with brain metastases.

Journal Of Translational Medicine

Wang, Zhen Z; Yu, Ruoying R; Chen, Xiaoxi X; Bao, Hua H; Cao, Ran R; Li, An-Na AN; Ou, Qiuxiang Q; Tu, Hai-Yan HY; Zhou, Qing Q; Wu, Xue X; Lin, Zhi-Bo ZB; Wu, Yi-Long YL

Publication Date: 2022-02-05

Variant appearance in text: EGF: L858R

PubMed Link: 35123506

Variant Present in the following documents:

• Main text

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Clinical utility of cerebrospinal fluid-derived circular RNAs in lung adenocarcinoma patients with brain metastases.

Journal Of Translational Medicine

Wang, Zhen Z; Yu, Ruoying R; Chen, Xiaoxi X; Bao, Hua H; Cao, Ran R; Li, An-Na AN; Ou, Qiuxiang Q; Tu, Hai-Yan HY; Zhou, Qing Q; Wu, Xue X; Lin, Zhi-Bo ZB; Wu, Yi-Long YL

Publication Date: 2022-02-05

Variant appearance in text: EGF: L858R

PubMed Link: 35123506

Variant Present in the following documents:

• Main text

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Estradiol-mediated inhibition of Sp1 decreases miR-3194-5p expression to enhance CD44 expression during lung cancer progression.

Journal Of Biomedical Science

Young, Ming-Jer MJ; Chen, Yung-Ching YC; Wang, Shao-An SA; Chang, Hui-Ping HP; Yang, Wen-Bin WB; Lee, Chia-Chi CC; Liu, Chia-Yu CY; Tseng, Yau-Lin YL; Wang, Yi-Ching YC; Sun, H Sunny HS; Chang, Wen-Chang WC; Hung, Jan-Jong JJ

Publication Date: 2022-01-17

Variant appearance in text: EGF: L858R

PubMed Link: 35034634

Variant Present in the following documents:

• Main text

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Estradiol-mediated inhibition of Sp1 decreases miR-3194-5p expression to enhance CD44 expression during lung cancer progression.

Journal Of Biomedical Science

Young, Ming-Jer MJ; Chen, Yung-Ching YC; Wang, Shao-An SA; Chang, Hui-Ping HP; Yang, Wen-Bin WB; Lee, Chia-Chi CC; Liu, Chia-Yu CY; Tseng, Yau-Lin YL; Wang, Yi-Ching YC; Sun, H Sunny HS; Chang, Wen-Chang WC; Hung, Jan-Jong JJ

Publication Date: 2022-01-17

Variant appearance in text: EGF: L858R

PubMed Link: 35034634

Variant Present in the following documents:

• Main text

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Current Immunotherapeutic Strategies Targeting the PD-1/PD-L1 Axis in Non-Small Cell Lung Cancer with Oncogenic Driver Mutations.

International Journal Of Molecular Sciences

Tanaka, Ichidai I; Morise, Masahiro M

Publication Date: 2021-12-27

Variant appearance in text: EGF: L858R

PubMed Link: 35008669

Variant Present in the following documents:

• Main text
• ijms-23-00245.pdf

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Current Immunotherapeutic Strategies Targeting the PD-1/PD-L1 Axis in Non-Small Cell Lung Cancer with Oncogenic Driver Mutations.

International Journal Of Molecular Sciences

Tanaka, Ichidai I; Morise, Masahiro M

Publication Date: 2021-12-27

Variant appearance in text: EGF: L858R

PubMed Link: 35008669

Variant Present in the following documents:

• Main text
• ijms-23-00245.pdf

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Small Molecule Calcium Channel Activator Potentiates Adjuvant Activity.

Acs Chemical Biology

Saito, Tetsuya T; Shukla, Nikunj M NM; Sato-Kaneko, Fumi F; Sako, Yukiya Y; Hosoya, Tadashi T; Yao, Shiyin S; Lao, Fitzgerald S FS; Messer, Karen K; Pu, Minya M; Chan, Michael M; Chu, Paul J PJ; Cottam, Howard B HB; Hayashi, Tomoko T; Carson, Dennis A DA; Corr, Maripat M

Publication Date: 2022-01-21

Variant appearance in text: EGF: L858R

PubMed Link: 34985883

Variant Present in the following documents:

• cb1c00883_si_001.pdf

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Emerging Importance of Tyrosine Kinase Inhibitors against Cancer: Quo Vadis to Cure?

International Journal Of Molecular Sciences

Mongre, Raj Kumar RK; Mishra, Chandra Bhushan CB; Shukla, Arvind Kumar AK; Prakash, Amresh A; Jung, Samil S; Ashraf-Uz-Zaman, Md M; Lee, Myeong-Sok MS

Publication Date: 2021-10-28

Variant appearance in text: EGF: L858R

PubMed Link: 34769090

Variant Present in the following documents:

• Main text
• ijms-22-11659.pdf

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Epidermal Growth Factor Receptor Mutations Carried in Extracellular Vesicle-Derived Cargo Mirror Disease Status in Metastatic Non-small Cell Lung Cancer.

Frontiers In Cell And Developmental Biology

Purcell, Emma E; Owen, Sarah S; Prantzalos, Emily E; Radomski, Abigail A; Carman, Nayri N; Lo, Ting-Wen TW; Zeinali, Mina M; Subramanian, Chitra C; Ramnath, Nithya N; Nagrath, Sunitha S

Publication Date: 2021

Variant appearance in text: EGF: L858R

PubMed Link: 34692681

Variant Present in the following documents:

• Main text

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Tumor microenvironment-based screening repurposes drugs targeting cancer stem cells and cancer-associated fibroblasts.

Theranostics

Lee, Pei-Jung PJ; Ho, Chao-Chi CC; Ho, Hao H; Chen, Wan-Jiun WJ; Lin, Chiu-Hua CH; Lai, Yi-Hua YH; Juan, Yi-Chen YC; Chu, Wen-Chung WC; Lee, Jia-Hua JH; Su, Sheng-Fang SF; Chen, Hsuan-Yu HY; Chen, Jeremy J W JJW; Chang, Gee-Chen GC; Li, Ker-Chau KC; Yang, Pan-Chyr PC; Chen, Huei-Wen HW

Publication Date: 2021

Variant appearance in text: EGF: L858R

PubMed Link: 34646392

Variant Present in the following documents:

• thnov11p9667s1.pdf

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: EGF: L858R

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

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Combined intermittent fasting and ERK inhibition enhance the anti-tumor effects of chemotherapy via the GSK3β-SIRT7 axis.

Nature Communications

Tang, Xiaolong X; Li, Guo G; Shi, Lei L; Su, Fengting F; Qian, Minxian M; Liu, Zuojun Z; Meng, Yuan Y; Sun, Shimin S; Li, Ji J; Liu, Baohua B

Publication Date: 2021-08-25

Variant appearance in text: EGF: L858R

PubMed Link: 34433808

Variant Present in the following documents:

• Main text

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PD-L2 based immune signature confers poor prognosis in HNSCC.

Oncoimmunology

Qiao, Yu Y; Liu, Chao C; Zhang, Xiaoyue X; Zhou, Qianqian Q; Li, Yatian Y; Xu, Yini Y; Gao, Zhenyue Z; Xu, Yiqi Y; Kong, Lingping L; Yang, Aifeng A; Mei, Mei M; Ren, Yu Y; Wang, Xudong X; Zhou, Xuan X

Publication Date: 2021

Variant appearance in text: EGF: L858R

PubMed Link: 34377590

Variant Present in the following documents:

• Main text
• KONI_10_1947569.pdf

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Structural basis of the effect of activating mutations on the EGF receptor.

Elife

Galdadas, Ioannis I; Carlino, Luca L; Ward, Richard A RA; Hughes, Samantha J SJ; Haider, Shozeb S; Gervasio, Francesco Luigi FL

Publication Date: 2021-07-28

Variant appearance in text: EGF: L858R

PubMed Link: 34319231

Variant Present in the following documents:

• Main text
• elife-65824.pdf

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EGFR in Cancer: Signaling Mechanisms, Drugs, and Acquired Resistance.

Cancers

Uribe, Mary Luz ML; Marrocco, Ilaria I; Yarden, Yosef Y

Publication Date: 2021-06-01

Variant appearance in text: EGF: L858R

PubMed Link: 34206026

Variant Present in the following documents:

• Main text

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Utilizing network pharmacology to explore potential mechanisms of YiSui NongJian formula in treating myelodysplastic syndrome.

Bioengineered

Qin, Lerong L; Chen, Haiyan H; Ding, Xiaoqing X; Guo, Ming M; Lang, Haiyan H; Liu, Junxia J; Li, Ling L; Liao, Jing J; Liao, Junyao J

Publication Date: 2021-12

Variant appearance in text: EGF: L858R

PubMed Link: 34098848

Variant Present in the following documents:

• KBIE_12_1933867.pdf

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A data-independent acquisition-based global phosphoproteomics system enables deep profiling.

Nature Communications

Kitata, Reta Birhanu RB; Choong, Wai-Kok WK; Tsai, Chia-Feng CF; Lin, Pei-Yi PY; Chen, Bo-Shiun BS; Chang, Yun-Chien YC; Nesvizhskii, Alexey I AI; Sung, Ting-Yi TY; Chen, Yu-Ju YJ

Publication Date: 2021-05-05

Variant appearance in text: EGF: L858R

PubMed Link: 33953186

Variant Present in the following documents:

• Main text

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PET and SPECT Imaging of the EGFR Family (RTK Class I) in Oncology.

International Journal Of Molecular Sciences

Rinne, Sara S SS; Orlova, Anna A; Tolmachev, Vladimir V

Publication Date: 2021-04-01

Variant appearance in text: EGF: L858R

PubMed Link: 33915894

Variant Present in the following documents:

• Main text

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Tofacitinib overcomes an IFNγ-induced decrease in NK cell-mediated cytotoxicity via the regulation of immune-related molecules in LC-2/ad.

Thoracic Cancer

Okita, Riki R; Shimizu, Katsuhiko K; Nojima, Yuji Y; Saisho, Shinsuke S; Nakata, Masao M

Publication Date: 2021-03

Variant appearance in text: EGF: L858R

PubMed Link: 33491334

Variant Present in the following documents:

• Main text
• TCA-12-775.pdf

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Flavonoids Regulate Inflammation and Oxidative Stress in Cancer.

Molecules (Basel, Switzerland)

Li, Guangxing G; Ding, Kaiyue K; Qiao, Yanling Y; Zhang, Liu L; Zheng, Luping L; Pan, Taowen T; Zhang, Lin L

Publication Date: 2020-11-30

Variant appearance in text: EGF: L858R

PubMed Link: 33265939

Variant Present in the following documents:

• Main text
• molecules-25-05628.pdf

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Tyrosine Kinase Receptors in Oncology.

International Journal Of Molecular Sciences

Esteban-Villarrubia, Jorge J; Soto-Castillo, Juan José JJ; Pozas, Javier J; San Román-Gil, María M; Orejana-Martín, Inmaculada I; Torres-Jiménez, Javier J; Carrato, Alfredo A; Alonso-Gordoa, Teresa T; Molina-Cerrillo, Javier J

Publication Date: 2020-11-12

Variant appearance in text: EGF: L858R

PubMed Link: 33198314

Variant Present in the following documents:

• Main text

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Differential Efficacy of Novel Antiviral Substances in 3D and Monolayer Cell Culture.

Viruses

Koban, Robert R; Neumann, Markus M; Nelson, Philipp P PP; Ellerbrok, Heinz H

Publication Date: 2020-11-12

Variant appearance in text: EGF: L858R

PubMed Link: 33198108

Variant Present in the following documents:

• Main text

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Beyond Conventional: The New Horizon of Anti-Angiogenic microRNAs in Non-Small Cell Lung Cancer Therapy.

International Journal Of Molecular Sciences

Tirpe, Alexandru A; Gulei, Diana D; Tirpe, George Razvan GR; Nutu, Andreea A; Irimie, Alexandru A; Campomenosi, Paola P; Pop, Laura Ancuta LA; Berindan-Neagoe, Ioana I

Publication Date: 2020-10-27

Variant appearance in text: EGF: L858R

PubMed Link: 33121202

Variant Present in the following documents:

• Main text
• ijms-21-08002.pdf

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Specific Targeting of Notch Ligand-Receptor Interactions to Modulate Immune Responses: A Review of Clinical and Preclinical Findings.

Frontiers In Immunology

Goruganthu, Mounika U L MUL; Shanker, Anil A; Dikov, Mikhail M MM; Carbone, David P DP

Publication Date: 2020

Variant appearance in text: EGF: L858R

PubMed Link: 32922403

Variant Present in the following documents:

• Main text

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Comprehensive Model for Epidermal Growth Factor Receptor Ligand Binding Involving Conformational States of the Extracellular and the Kinase Domains.

Frontiers In Cell And Developmental Biology

Hajdu, Tímea T; Váradi, Tímea T; Rebenku, István I; Kovács, Tamás T; Szöllösi, János J; Nagy, Peter P

Publication Date: 2020

Variant appearance in text: EGF: L858R

PubMed Link: 32850868

Variant Present in the following documents:

• Main text
• fcell-08-00776.pdf

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erbB in NSCLC as a molecular target: current evidences and future directions.

Esmo Open

Del Re, Marzia M; Cucchiara, Federico F; Petrini, Iacopo I; Fogli, Stefano S; Passaro, Antonio A; Crucitta, Stefania S; Attili, Ilaria I; De Marinis, Filippo F; Chella, Antonio A; Danesi, Romano R

Publication Date: 2020-08

Variant appearance in text: EGF: L858R

PubMed Link: 32820012

Variant Present in the following documents:

• Main text

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Patient specific circulating tumor DNA fingerprints to monitor treatment response across multiple tumors.

Journal Of Translational Medicine

Li, Jiaping J; Jiang, Wei W; Wei, Jinwang J; Zhang, Jianwei J; Cai, Linbo L; Luo, Minjie M; Wang, Zhan Z; Sun, Wending W; Wang, Shengzhou S; Wang, Chen C; Dai, Chun C; Liu, Jun J; Wang, Guan G; Wang, Jiping J; Xu, Qiang Q; Deng, Yanhong Y

Publication Date: 2020-08-01

Variant appearance in text: EGF: L858R

PubMed Link: 32738923

Variant Present in the following documents:

• 12967_2020_2449_MOESM2_ESM.xlsx, sheet 1

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Genomic characteristics and drug screening among organoids derived from non-small cell lung cancer patients.

Thoracic Cancer

Chen, Jing-Hua JH; Chu, Xiang-Peng XP; Zhang, Jia-Tao JT; Nie, Qiang Q; Tang, Wen-Fang WF; Su, Jian J; Yan, Hong-Hong HH; Zheng, Hong-Ping HP; Chen, Ze-Xin ZX; Chen, Xin X; Song, Meng-Meng MM; Yi, Xin X; Li, Pan-Song PS; Guan, Yan-Fang YF; Li, Gang G; Deng, Chu-Xia CX; Rosell, Rafael R; Wu, Yi-Long YL; Zhong, Wen-Zhao WZ

Publication Date: 2020-08

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PubMed Link: 32633046

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Top Notch Targeting Strategies in Cancer: A Detailed Overview of Recent Insights and Current Perspectives.

Cells

Moore, Gillian G; Annett, Stephanie S; McClements, Lana L; Robson, Tracy T

Publication Date: 2020-06-20

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PubMed Link: 32575680

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• cells-09-01503.pdf

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ERBB2/HER2 mutations are transforming and therapeutically targetable in leukemia.

Leukemia

Joshi, Sunil K SK; Keck, Jamie M JM; Eide, Christopher A CA; Bottomly, Daniel D; Traer, Elie E; Tyner, Jeffrey W JW; McWeeney, Shannon K SK; Tognon, Cristina E CE; Druker, Brian J BJ

Publication Date: 2020-10

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PubMed Link: 32366937

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CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities.

Nature

Han, Kyuho K; Pierce, Sarah E SE; Li, Amy A; Spees, Kaitlyn K; Anderson, Gray R GR; Seoane, Jose A JA; Lo, Yuan-Hung YH; Dubreuil, Michael M; Olivas, Micah M; Kamber, Roarke A RA; Wainberg, Michael M; Kostyrko, Kaja K; Kelly, Marcus R MR; Yousefi, Maryam M; Simpkins, Scott W SW; Yao, David D; Lee, Keonil K; Kuo, Calvin J CJ; Jackson, Peter K PK; Sweet-Cordero, Alejandro A; Kundaje, Anshul A; Gentles, Andrew J AJ; Curtis, Christina C; Winslow, Monte M MM; Bassik, Michael C MC

Publication Date: 2020-04

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PubMed Link: 32238925

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CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities.

Nature

Han, Kyuho K; Pierce, Sarah E SE; Li, Amy A; Spees, Kaitlyn K; Anderson, Grace R GR; Seoane, Jose A JA; Lo, Yuan-Hung YH; Dubreuil, Michael M; Olivas, Micah M; Kamber, Roarke A RA; Wainberg, Michael M; Kostyrko, Kaja K; Kelly, Marcus R MR; Yousefi, Maryam M; Simpkins, Scott W SW; Yao, David D; Lee, Keonil K; Kuo, Calvin J CJ; Jackson, Peter K PK; Sweet-Cordero, Alejandro A; Kundaje, Anshul A; Gentles, Andrew J AJ; Curtis, Christina C; Winslow, Monte M MM; Bassik, Michael C MC

Publication Date: 2020-04

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PubMed Link: 32238925

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Spectroscopic and molecular docking studies reveal binding characteristics of nazartinib (EGF816) to human serum albumin.

Royal Society Open Science

Almehizia, Abdulrahman A AA; AlRabiah, Haitham H; Bakheit, Ahmed H AH; Hassan, Eman S G ESG; Herqash, Rashed N RN; Abdelhameed, Ali Saber AS

Publication Date: 2020-01

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PubMed Link: 32218978

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The Fabrication and Application Mechanism of Microfluidic Systems for High Throughput Biomedical Screening: A Review.

Micromachines

Song, Kena K; Li, Guoqiang G; Zu, Xiangyang X; Du, Zhe Z; Liu, Liyu L; Hu, Zhigang Z

Publication Date: 2020-03-11

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PubMed Link: 32168977

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

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PubMed Link: 32107691

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Multiple Growth Factor Targeting by Engineered Insulin-like Growth Factor Binding Protein-3 Augments EGF Receptor Tyrosine Kinase Inhibitor Efficacy.

Scientific Reports

Wang, Elizabeth A EA; Chen, Wan-Yu WY; Wong, Chi-Huey CH

Publication Date: 2020-02-17

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PubMed Link: 32066763

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Bempegaldesleukin selectively depletes intratumoral Tregs and potentiates T cell-mediated cancer therapy.

Nature Communications

Sharma, Meenu M; Khong, Hiep H; Fa'ak, Faisal F; Bentebibel, Salah-Eddine SE; Janssen, Louise M E LME; Chesson, Brent C BC; Creasy, Caitlin A CA; Forget, Marie-Andrée MA; Kahn, Laura Maria S LMS; Pazdrak, Barbara B; Karki, Binisha B; Hailemichael, Yared Y; Singh, Manisha M; Vianden, Christina C; Vennam, Srinivas S; Bharadwaj, Uddalak U; Tweardy, David J DJ; Haymaker, Cara C; Bernatchez, Chantale C; Huang, Shixia S; Rajapakshe, Kimal K; Coarfa, Cristian C; Hurwitz, Michael E ME; Sznol, Mario M; Hwu, Patrick P; Hoch, Ute U; Addepalli, Murali M; Charych, Deborah H DH; Zalevsky, Jonathan J; Diab, Adi A; Overwijk, Willem W WW

Publication Date: 2020-01-31

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PubMed Link: 32005826

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MicroRNAs in non-small cell lung cancer: Gene regulation, impact on cancer cellular processes, and therapeutic potential.

Pharmacology Research & Perspectives

Petrek, Hannah H; Yu, Ai-Ming AM

Publication Date: 2019-12

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PubMed Link: 31859460

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Triple blockade of EGFR, MEK and PD-L1 has antitumor activity in colorectal cancer models with constitutive activation of MAPK signaling and PD-L1 overexpression.

Journal Of Experimental & Clinical Cancer Research : Cr

Napolitano, S S; Matrone, N N; Muddassir, A L AL; Martini, G G; Sorokin, A A; De Falco, V V; Giunta, E F EF; Ciardiello, D D; Martinelli, E E; Belli, V V; Furia, M M; Kopetz, S S; Morgillo, F F; Ciardiello, F F; Troiani, T T

Publication Date: 2019-12-16

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PubMed Link: 31842958

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EGF suppresses the expression of miR-124a in pancreatic β cell lines via ETS2 activation through the MEK and PI3K signaling pathways.

International Journal Of Biological Sciences

Yang, Lin L; Zhu, Yuansen Y; Kong, Delin D; Gong, Jiawei J; Yu, Wen W; Liang, Yang Y; Nie, Yuzhe Y; Teng, Chun-Bo CB

Publication Date: 2019

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PubMed Link: 31754329

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Downregulation of miR-552 in hepatocellular carcinoma inhibits cell migration and invasion, and promotes cell apoptosis via RUNX3.

Experimental And Therapeutic Medicine

Ma, Ying Y; Ma, Ming M; Ma, Ling L; Zhang, Fengbo F; Liu, Yumei Y; Ma, Xiumin X

Publication Date: 2019-11

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PubMed Link: 31656538

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The efficacy of immune checkpoint inhibitors in advanced non-small cell lung cancer harboring driver mutations.

Molecular And Clinical Oncology

Sakamoto, Hiroaki H; Tanaka, Hisashi H; Shiratori, Toshihiro T; Baba, Keisuke K; Ishioka, Yoshiko Y; Itoga, Masamichi M; Taima, Kageaki K; Hasegawa, Yukihiro Y; Takanashi, Shingo S; Tasaka, Sadatomo S

Publication Date: 2019-06

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PubMed Link: 31031976

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MERTK mediated novel site Akt phosphorylation alleviates SAV1 suppression.

Nature Communications

Jiang, Yao Y; Zhang, Yanqiong Y; Leung, Janet Y JY; Fan, Cheng C; Popov, Konstantin I KI; Su, Siyuan S; Qian, Jiayi J; Wang, Xiaodong X; Holtzhausen, Alisha A; Ubil, Eric E; Xiang, Yang Y; Davis, Ian I; Dokholyan, Nikolay V NV; Wu, Gang G; Perou, Charles M CM; Kim, William Y WY; Earp, H Shelton HS; Liu, Pengda P

Publication Date: 2019-04-03

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PubMed Link: 30944303

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