Publications:

---

Autophosphorylation of EGFR at Y954 Facilitated Homodimerization and Enhanced Downstream Signals.

Biophysical Journal

Thirukkumaran, Ovia M OM; Kluba, Malgorzata M; Hofkens, Johan J; Mizuno, Hideaki H

Publication Date: 2020-11-17

Variant appearance in text: EGF: Y992F

PubMed Link: 33096081

Variant Present in the following documents:

• Main text

View BVdb publication page

---

EGFR activation attenuates the mechanical threshold for integrin tension and focal adhesion formation.

Journal Of Cell Science

Rao, Tejeshwar C TC; Ma, Victor Pui-Yan VP; Blanchard, Aaron A; Urner, Tara M TM; Grandhi, Shreya S; Salaita, Khalid K; Mattheyses, Alexa L AL

Publication Date: 2020-07-10

Variant appearance in text: EGF: Y992F

PubMed Link: 32546532

Variant Present in the following documents:

• Main text

View BVdb publication page

---

A specific amino acid context in EGFR and HER2 phosphorylation sites enables selective binding to the active site of Src homology phosphatase 2 (SHP2).

The Journal Of Biological Chemistry

Hartman, Zachary Z; Geldenhuys, Werner J WJ; Agazie, Yehenew M YM

Publication Date: 2020-03-13

Variant appearance in text: EGF: Y992F

PubMed Link: 32024694

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Design and evaluation of engineered protein biosensors for live-cell imaging of EGFR phosphorylation.

Science Signaling

Tiruthani, Karthik K; Mischler, Adam A; Ahmed, Shoeb S; Mahinthakumar, Jessica J; Haugh, Jason M JM; Rao, Balaji M BM

Publication Date: 2019-06-04

Variant appearance in text: EGF: Y992F

PubMed Link: 31164479

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Inhibition of Receptor Dimerization as a Novel Negative Feedback Mechanism of EGFR Signaling.

Plos One

Kluba, Malgorzata M; Engelborghs, Yves Y; Hofkens, Johan J; Mizuno, Hideaki H

Publication Date: 2015

Variant appearance in text: EGF: Y992F

PubMed Link: 26465157

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Analytical reduction of combinatorial complexity arising from multiple protein modification sites.

Journal Of The Royal Society, Interface

Birtwistle, Marc R MR

Publication Date: 2015-02-06

Variant appearance in text: EGF: Y992F

PubMed Link: 25519995

Variant Present in the following documents:

• Main text

View BVdb publication page

---

EGFR ligands exhibit functional differences in models of paracrine and autocrine signaling.

Growth Factors (Chur, Switzerland)

Wilson, Kristy J KJ; Mill, Christopher C; Lambert, Sydney S; Buchman, Jennifer J; Wilson, Timothy R TR; Hernandez-Gordillo, Victor V; Gallo, Richard M RM; Ades, Laura M C LM; Settleman, Jeffrey J; Riese, David J DJ

Publication Date: 2012-04

Variant appearance in text: EGF: Y992F

PubMed Link: 22260327

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Specific epidermal growth factor receptor autophosphorylation sites promote mouse colon epithelial cell chemotaxis and restitution.

American Journal Of Physiology. Gastrointestinal And Liver Physiology

Yamaoka, Toshimitsu T; Frey, Mark R MR; Dise, Rebecca S RS; Bernard, Jessica K JK; Polk, D Brent DB

Publication Date: 2011-08

Variant appearance in text: EGF: Y992F

PubMed Link: 21617115

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Phosphoproteomics-based modeling defines the regulatory mechanism underlying aberrant EGFR signaling.

Plos One

Tasaki, Shinya S; Nagasaki, Masao M; Kozuka-Hata, Hiroko H; Semba, Kentaro K; Gotoh, Noriko N; Hattori, Seisuke S; Inoue, Jun-ichiro J; Yamamoto, Tadashi T; Miyano, Satoru S; Sugano, Sumio S; Oyama, Masaaki M

Publication Date: 2010-11-10

Variant appearance in text: EGF: Y992F

PubMed Link: 21085658

Variant Present in the following documents:

• Main text
• pone.0013926.pdf

View BVdb publication page

---

Molecular mechanism for a role of SHP2 in epidermal growth factor receptor signaling.

Molecular And Cellular Biology

Agazie, Yehenew M YM; Hayman, Michael J MJ

Publication Date: 2003-11

Variant appearance in text: EGF: Y992F

PubMed Link: 14560030

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Class II phosphoinositide 3-kinases are downstream targets of activated polypeptide growth factor receptors.

Molecular And Cellular Biology

Arcaro, A A; Zvelebil, M J MJ; Wallasch, C C; Ullrich, A A; Waterfield, M D MD; Domin, J J

Publication Date: 2000-06

Variant appearance in text: EGF: Y992F

PubMed Link: 10805725

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Phosphorylation of tyrosine 992, 1068, and 1086 is required for conformational change of the human epidermal growth factor receptor c-terminal tail.

Molecular Biology Of The Cell

Bishayee, A A; Beguinot, L L; Bishayee, S S

Publication Date: 1999-03

Variant appearance in text: EGF: Y992F

PubMed Link: 10069801

Variant Present in the following documents:

• Main text

View BVdb publication page

---