Constructing a polygenic risk score for childhood obesity using functional data analysis.
Econometrics And Statistics
Craig, Sarah J C SJC; Kenney, Ana M AM; Lin, Junli J; Paul, Ian M IM; Birch, Leann L LL; Savage, Jennifer S JS; Marini, Michele E ME; Chiaromonte, Francesca F; Reimherr, Matthew L ML; Makova, Kateryna D KD
Genomic, transcriptomic, and metabolomic profiles of hiPSC-derived dopamine neurons from clinically discordant brothers with identical PRKN deletions.
Npj Parkinson'S Disease
Cukier, Holly N HN; Kim, Hyunjin H; Griswold, Anthony J AJ; Codreanu, Simona G SG; Prince, Lisa M LM; Sherrod, Stacy D SD; McLean, John A JA; Dykxhoorn, Derek M DM; Ess, Kevin C KC; Hedera, Peter P; Bowman, Aaron B AB; Neely, M Diana MD
Publication Date: 2022-06-29
Variant appearance in text: HHIP: I686I; rs11727676
Associations Between Glycemic Traits and Colorectal Cancer: A Mendelian Randomization Analysis.
Journal Of The National Cancer Institute
Murphy, Neil N; Song, Mingyang M; Papadimitriou, Nikos N; Carreras-Torres, Robert R; Langenberg, Claudia C; Martin, Richard M RM; Tsilidis, Konstantinos K KK; Barroso, Inês I; Chen, Ji J; Frayling, Timothy M TM; Bull, Caroline J CJ; Vincent, Emma E EE; Cotterchio, Michelle M; Gruber, Stephen B SB; Pai, Rish K RK; Newcomb, Polly A PA; Perez-Cornago, Aurora A; van Duijnhoven, Franzel J B FJB; Van Guelpen, Bethany B; Vodicka, Pavel P; Wolk, Alicja A; Wu, Anna H AH; Peters, Ulrike U; Chan, Andrew T AT; Gunter, Marc J MJ
The Role of Inflammatory Cytokines as Intermediates in the Pathway from Increased Adiposity to Disease.
Obesity (Silver Spring, Md.)
Kalaoja, Marita M; Corbin, Laura J LJ; Tan, Vanessa Y VY; Ahola-Olli, Ari V AV; Havulinna, Aki S AS; Santalahti, Kristiina K; Pitkänen, Niina N; Lehtimäki, Terho T; Lyytikäinen, Leo-Pekka LP; Raitoharju, Emma E; Seppälä, Ilkka I; Kähönen, Mika M; Ripatti, Samuli S; Palotie, Aarno A; Perola, Markus M; Viikari, Jorma S JS; Jalkanen, Sirpa S; Maksimow, Mikael M; Salomaa, Veikko V; Salmi, Marko M; Raitakari, Olli T OT; Kettunen, Johannes J; Timpson, Nicholas J NJ
Distinctive mutational spectrum and karyotype disruption in long-term cisplatin-treated urothelial carcinoma cell lines.
Scientific Reports
Skowron, Margaretha A MA; Petzsch, Patrick P; Hardt, Karin K; Wagner, Nicholas N; Beier, Manfred M; Stepanow, Stefanie S; Drechsler, Matthias M; Rieder, Harald H; Köhrer, Karl K; Niegisch, Günter G; Hoffmann, Michèle J MJ; Schulz, Wolfgang A WA
Publication Date: 2019-10-09
Variant appearance in text: HHIP: I686I; rs11727676
The expression of genes in top obesity-associated loci is enriched in insula and substantia nigra brain regions involved in addiction and reward.
International Journal Of Obesity (2005)
Ndiaye, Fatou K FK; Huyvaert, Marlène M; Ortalli, Ana A; Canouil, Mickaël M; Lecoeur, Cécile C; Verbanck, Marie M; Lobbens, Stéphane S; Khamis, Amna A; Marselli, Lorella L; Marchetti, Piero P; Kerr-Conte, Julie J; Pattou, François F; Marre, Michel M; Roussel, Ronan R; Balkau, Beverley B; Froguel, Philippe P; Bonnefond, Amélie A
Body mass index and all cause mortality in HUNT and UK Biobank studies: linear and non-linear mendelian randomisation analyses.
Bmj (Clinical Research Ed.)
Sun, Yi-Qian YQ; Burgess, Stephen S; Staley, James R JR; Wood, Angela M AM; Bell, Steven S; Kaptoge, Stephen K SK; Guo, Qi Q; Bolton, Thomas R TR; Mason, Amy M AM; Butterworth, Adam S AS; Di Angelantonio, Emanuele E; Vie, Gunnhild Å GÅ; Bjørngaard, Johan H JH; Kinge, Jonas Minet JM; Chen, Yue Y; Mai, Xiao-Mei XM
Discovery of common and rare genetic risk variants for colorectal cancer.
Nature Genetics
Huyghe, Jeroen R JR; Bien, Stephanie A SA; Harrison, Tabitha A TA; Kang, Hyun Min HM; Chen, Sai S; Schmit, Stephanie L SL; Conti, David V DV; Qu, Conghui C; Jeon, Jihyoun J; Edlund, Christopher K CK; Greenside, Peyton P; Wainberg, Michael M; Schumacher, Fredrick R FR; Smith, Joshua D JD; Levine, David M DM; Nelson, Sarah C SC; Sinnott-Armstrong, Nasa A NA; Albanes, Demetrius D; Alonso, M Henar MH; Anderson, Kristin K; Arnau-Collell, Coral C; Arndt, Volker V; Bamia, Christina C; Banbury, Barbara L BL; Baron, John A JA; Berndt, Sonja I SI; Bézieau, Stéphane S; Bishop, D Timothy DT; Boehm, Juergen J; Boeing, Heiner H; Brenner, Hermann H; Brezina, Stefanie S; Buch, Stephan S; Buchanan, Daniel D DD; Burnett-Hartman, Andrea A; Butterbach, Katja K; Caan, Bette J BJ; Campbell, Peter T PT; Carlson, Christopher S CS; Castellví-Bel, Sergi S; Chan, Andrew T AT; Chang-Claude, Jenny J; Chanock, Stephen J SJ; Chirlaque, Maria-Dolores MD; Cho, Sang Hee SH; Connolly, Charles M CM; Cross, Amanda J AJ; Cuk, Katarina K; Curtis, Keith R KR; de la Chapelle, Albert A; Doheny, Kimberly F KF; Duggan, David D; Easton, Douglas F DF; Elias, Sjoerd G SG; Elliott, Faye F; English, Dallas R DR; Feskens, Edith J M EJM; Figueiredo, Jane C JC; Fischer, Rocky R; FitzGerald, Liesel M LM; Forman, David D; Gala, Manish M; Gallinger, Steven S; Gauderman, W James WJ; Giles, Graham G GG; Gillanders, Elizabeth E; Gong, Jian J; Goodman, Phyllis J PJ; Grady, William M WM; Grove, John S JS; Gsur, Andrea A; Gunter, Marc J MJ; Haile, Robert W RW; Hampe, Jochen J; Hampel, Heather H; Harlid, Sophia S; Hayes, Richard B RB; Hofer, Philipp P; Hoffmeister, Michael M; Hopper, John L JL; Hsu, Wan-Ling WL; Huang, Wen-Yi WY; Hudson, Thomas J TJ; Hunter, David J DJ; Ibañez-Sanz, Gemma G; Idos, Gregory E GE; Ingersoll, Roxann R; Jackson, Rebecca D RD; Jacobs, Eric J EJ; Jenkins, Mark A MA; Joshi, Amit D AD; Joshu, Corinne E CE; Keku, Temitope O TO; Key, Timothy J TJ; Kim, Hyeong Rok HR; Kobayashi, Emiko E; Kolonel, Laurence N LN; Kooperberg, Charles C; Kühn, Tilman T; Küry, Sébastien S; Kweon, Sun-Seog SS; Larsson, Susanna C SC; Laurie, Cecelia A CA; Le Marchand, Loic L; Leal, Suzanne M SM; Lee, Soo Chin SC; Lejbkowicz, Flavio F; Lemire, Mathieu M; Li, Christopher I CI; Li, Li L; Lieb, Wolfgang W; Lin, Yi Y; Lindblom, Annika A; Lindor, Noralane M NM; Ling, Hua H; Louie, Tin L TL; Männistö, Satu S; Markowitz, Sanford D SD; Martín, Vicente V; Masala, Giovanna G; McNeil, Caroline E CE; Melas, Marilena M; Milne, Roger L RL; Moreno, Lorena L; Murphy, Neil N; Myte, Robin R; Naccarati, Alessio A; Newcomb, Polly A PA; Offit, Kenneth K; Ogino, Shuji S; Onland-Moret, N Charlotte NC; Pardini, Barbara B; Parfrey, Patrick S PS; Pearlman, Rachel R; Perduca, Vittorio V; Pharoah, Paul D P PDP; Pinchev, Mila M; Platz, Elizabeth A EA; Prentice, Ross L RL; Pugh, Elizabeth E; Raskin, Leon L; Rennert, Gad G; Rennert, Hedy S HS; Riboli, Elio E; Rodríguez-Barranco, Miguel M; Romm, Jane J; Sakoda, Lori C LC; Schafmayer, Clemens C; Schoen, Robert E RE; Seminara, Daniela D; Shah, Mitul M; Shelford, Tameka T; Shin, Min-Ho MH; Shulman, Katerina K; Sieri, Sabina S; Slattery, Martha L ML; Southey, Melissa C MC; Stadler, Zsofia K ZK; Stegmaier, Christa C; Su, Yu-Ru YR; Tangen, Catherine M CM; Thibodeau, Stephen N SN; Thomas, Duncan C DC; Thomas, Sushma S SS; Toland, Amanda E AE; Trichopoulou, Antonia A; Ulrich, Cornelia M CM; Van Den Berg, David J DJ; van Duijnhoven, Franzel J B FJB; Van Guelpen, Bethany B; van Kranen, Henk H; Vijai, Joseph J; Visvanathan, Kala K; Vodicka, Pavel P; Vodickova, Ludmila L; Vymetalkova, Veronika V; Weigl, Korbinian K; Weinstein, Stephanie J SJ; White, Emily E; Win, Aung Ko AK; Wolf, C Roland CR; Wolk, Alicja A; Woods, Michael O MO; Wu, Anna H AH; Zaidi, Syed H SH; Zanke, Brent W BW; Zhang, Qing Q; Zheng, Wei W; Scacheri, Peter C PC; Potter, John D JD; Bassik, Michael C MC; Kundaje, Anshul A; Casey, Graham G; Moreno, Victor V; Abecasis, Goncalo R GR; Nickerson, Deborah A DA; Gruber, Stephen B SB; Hsu, Li L; Peters, Ulrike U
Evaluation of the causal effects between subjective wellbeing and cardiometabolic health: mendelian randomisation study.
Bmj (Clinical Research Ed.)
Wootton, Robyn E RE; Lawn, Rebecca B RB; Millard, Louise A C LAC; Davies, Neil M NM; Taylor, Amy E AE; Munafò, Marcus R MR; Timpson, Nicholas J NJ; Davis, Oliver S P OSP; Davey Smith, George G; Haworth, Claire M A CMA
A high throughput, functional screen of human Body Mass Index GWAS loci using tissue-specific RNAi Drosophila melanogaster crosses.
Plos Genetics
Baranski, Thomas J TJ; Kraja, Aldi T AT; Fink, Jill L JL; Feitosa, Mary M; Lenzini, Petra A PA; Borecki, Ingrid B IB; Liu, Ching-Ti CT; Cupples, L Adrienne LA; North, Kari E KE; Province, Michael A MA
Interplay between genetic predisposition, macronutrient intake and type 2 diabetes incidence: analysis within EPIC-InterAct across eight European countries.
Diabetologia
Li, Sherly X SX; Imamura, Fumiaki F; Schulze, Matthias B MB; Zheng, Jusheng J; Ye, Zheng Z; Agudo, Antonio A; Ardanaz, Eva E; Aune, Dagfinn D; Boeing, Heiner H; Dorronsoro, Miren M; Dow, Courtney C; Fagherazzi, Guy G; Grioni, Sara S; Gunter, Marc J MJ; Huerta, José María JM; Ibsen, Daniel B DB; Jakobsen, Marianne Uhre MU; Kaaks, Rudolf R; Key, Timothy J TJ; Khaw, Kay-Tee KT; Kyrø, Cecilie C; Mancini, Francesca Romana FR; Molina-Portillo, Elena E; Murphy, Neil N; Nilsson, Peter M PM; Onland-Moret, N Charlotte NC; Palli, Domenico D; Panico, Salvatore S; Poveda, Alaitz A; Quirós, J Ramón JR; Ricceri, Fulvio F; Sluijs, Ivonne I; Spijkerman, Annemieke M W AMW; Tjonneland, Anne A; Tumino, Rosario R; Winkvist, Anna A; Langenberg, Claudia C; Sharp, Stephen J SJ; Riboli, Elio E; Scott, Robert A RA; Forouhi, Nita G NG; Wareham, Nicholas J NJ
A large electronic-health-record-based genome-wide study of serum lipids.
Nature Genetics
Hoffmann, Thomas J TJ; Theusch, Elizabeth E; Haldar, Tanushree T; Ranatunga, Dilrini K DK; Jorgenson, Eric E; Medina, Marisa W MW; Kvale, Mark N MN; Kwok, Pui-Yan PY; Schaefer, Catherine C; Krauss, Ronald M RM; Iribarren, Carlos C; Risch, Neil N
Prediction of Adulthood Obesity Using Genetic and Childhood Clinical Risk Factors in the Cardiovascular Risk in Young Finns Study.
Circulation. Cardiovascular Genetics
Seyednasrollah, Fatemeh F; Mäkelä, Johanna J; Pitkänen, Niina N; Juonala, Markus M; Hutri-Kähönen, Nina N; Lehtimäki, Terho T; Viikari, Jorma J; Kelly, Tanika T; Li, Changwei C; Bazzano, Lydia L; Elo, Laura L LL; Raitakari, Olli T OT
Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study.
Plos Medicine
Noyce, Alastair J AJ; Kia, Demis A DA; Hemani, Gibran G; Nicolas, Aude A; Price, T Ryan TR; De Pablo-Fernandez, Eduardo E; Haycock, Philip C PC; Lewis, Patrick A PA; Foltynie, Thomas T; Davey Smith, George G; , ; Schrag, Anette A; Lees, Andrew J AJ; Hardy, John J; Singleton, Andrew A; Nalls, Mike A MA; Pearce, Neil N; Lawlor, Debbie A DA; Wood, Nicholas W NW
Appetitive traits as behavioural pathways in genetic susceptibility to obesity: a population-based cross-sectional study.
Scientific Reports
Konttinen, Hanna H; Llewellyn, Clare C; Wardle, Jane J; Silventoinen, Karri K; Joensuu, Anni A; Männistö, Satu S; Salomaa, Veikko V; Jousilahti, Pekka P; Kaprio, Jaakko J; Perola, Markus M; Haukkala, Ari A
Genetic studies of body mass index yield new insights for obesity biology.
Nature
Locke, Adam E AE; Kahali, Bratati B; Berndt, Sonja I SI; Justice, Anne E AE; Pers, Tune H TH; Day, Felix R FR; Powell, Corey C; Vedantam, Sailaja S; Buchkovich, Martin L ML; Yang, Jian J; Croteau-Chonka, Damien C DC; Esko, Tonu T; Fall, Tove T; Ferreira, Teresa T; Gustafsson, Stefan S; Kutalik, Zoltán Z; Luan, Jian'an J; Mägi, Reedik R; Randall, Joshua C JC; Winkler, Thomas W TW; Wood, Andrew R AR; Workalemahu, Tsegaselassie T; Faul, Jessica D JD; Smith, Jennifer A JA; Zhao, Jing Hua JH; Zhao, Wei W; Chen, Jin J; Fehrmann, Rudolf R; Hedman, Åsa K ÅK; Karjalainen, Juha J; Schmidt, Ellen M EM; Absher, Devin D; Amin, Najaf N; Anderson, Denise D; Beekman, Marian M; Bolton, Jennifer L JL; Bragg-Gresham, Jennifer L JL; Buyske, Steven S; Demirkan, Ayse A; Deng, Guohong G; Ehret, Georg B GB; Feenstra, Bjarke B; Feitosa, Mary F MF; Fischer, Krista K; Goel, Anuj A; Gong, Jian J; Jackson, Anne U AU; Kanoni, Stavroula S; Kleber, Marcus E ME; Kristiansson, Kati K; Lim, Unhee U; Lotay, Vaneet V; Mangino, Massimo M; 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Whole-genome sequencing of the world's oldest people.
Plos One
Gierman, Hinco J HJ; Fortney, Kristen K; Roach, Jared C JC; Coles, Natalie S NS; Li, Hong H; Glusman, Gustavo G; Markov, Glenn J GJ; Smith, Justin D JD; Hood, Leroy L; Coles, L Stephen LS; Kim, Stuart K SK
Publication Date: 2014
Variant appearance in text: HHIP: I686I; rs11727676
Mutational analysis of hedgehog signaling pathway genes in human malignant mesothelioma.
Plos One
Lim, Chuan Bian CB; Prêle, Cecilia M CM; Cheah, Hui Min HM; Cheng, Yuen Yee YY; Klebe, Sonja S; Reid, Glen G; Watkins, D Neil DN; Baltic, Svetlana S; Thompson, Philip J PJ; Mutsaers, Steven E SE
Publication Date: 2013
Variant appearance in text: HHIP: I686I; rs11727676