DNA sequence variants in PPARGC1A, a gene encoding a coactivator of the ω-3 LCPUFA sensing PPAR-RXR transcription complex, are associated with NV AMD and AMD-associated loci in genes of complement and VEGF signaling pathways.
Plos One
SanGiovanni, John Paul JP; Chen, Jing J; Sapieha, Przemyslaw P; Aderman, Christopher M CM; Stahl, Andreas A; Clemons, Traci E TE; Chew, Emily Y EY; Smith, Lois E H LE