Microsecond-timescale MD simulation of EGFR minor mutation predicts the structural flexibility of EGFR kinase core that reflects EGFR inhibitor sensitivity.
Npj Precision Oncology
Yoshizawa, Takahiro T; Uchibori, Ken K; Araki, Mitsugu M; Matsumoto, Shigeyuki S; Ma, Biao B; Kanada, Ryo R; Seto, Yosuke Y; Oh-Hara, Tomoko T; Koike, Sumie S; Ariyasu, Ryo R; Kitazono, Satoru S; Ninomiya, Hironori H; Takeuchi, Kengo K; Yanagitani, Noriko N; Takagi, Satoshi S; Kishi, Kazuma K; Fujita, Naoya N; Okuno, Yasushi Y; Nishio, Makoto M; Katayama, Ryohei R
Publication Date: 2021-04-16
Variant appearance in text: PDGFRA: 1558+119T>C; rs869978
Intraventricular meningiomas frequently harbor NF2 mutations but lack common genetic alterations in TRAF7, AKT1, SMO, KLF4, PIK3CA, and TERT.
Acta Neuropathologica Communications
Jungwirth, Gerhard G; Warta, Rolf R; Beynon, Christopher C; Sahm, Felix F; von Deimling, Andreas A; Unterberg, Andreas A; Herold-Mende, Christel C; Jungk, Christine C
Attenuated PDGF signaling drives alveolar and microvascular defects in neonatal chronic lung disease.
Embo Molecular Medicine
Oak, Prajakta P; Pritzke, Tina T; Thiel, Isabella I; Koschlig, Markus M; Mous, Daphne S DS; Windhorst, Anita A; Jain, Noopur N; Eickelberg, Oliver O; Foerster, Kai K; Schulze, Andreas A; Goepel, Wolfgang W; Reicherzer, Tobias T; Ehrhardt, Harald H; Rottier, Robbert J RJ; Ahnert, Peter P; Gortner, Ludwig L; Desai, Tushar J TJ; Hilgendorff, Anne A