KIT c.292_293delinsGG ;(p.T98G)

Variant ID: 4-55561902-AC-GG

NM_000222.2(KIT):c.292_293delinsGG;(p.T98G)

This variant was identified in 27 publications

View GRCh38 version.




Publications:


miR-218-5p/RUNX2 Axis Positively Regulates Proliferation and Is Associated with Poor Prognosis in Cervical Cancer.

International Journal Of Molecular Sciences
Cruz-De la Rosa, Merlin Itsel MI; Jiménez-Wences, Hilda H; Alarcón-Millán, Judit J; Romero-López, Manuel Joaquín MJ; Castañón-Sánchez, Carlos Alberto CA; Salmerón-Bárcenas, Eric Genaro EG; Fernández-Tilapa, Gloria G
Publication Date: 2022-06-23

Variant appearance in text: KIT: T98G
PubMed Link: 35805994
Variant Present in the following documents:
  • Main text
  • ijms-23-06993.pdf
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miR-3189-targeted GLUT3 repression by HDAC2 knockdown inhibits glioblastoma tumorigenesis through regulating glucose metabolism and proliferation.

Journal Of Experimental & Clinical Cancer Research : Cr
Kwak, Sungmin S; Park, Seung-Ho SH; Kim, Sung-Hak SH; Sung, Gi-Jun GJ; Song, Ji-Hye JH; Jeong, Ji-Hoon JH; Kim, Hyunhee H; Ha, Chang Hoon CH; Kim, Seong Who SW; Choi, Kyung-Chul KC
Publication Date: 2022-03-08

Variant appearance in text: KIT: T98G
PubMed Link: 35260183
Variant Present in the following documents:
  • 13046_2022_2305_MOESM2_ESM.pdf
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Altered Elemental Distribution in Male Rat Brain Tissue as a Predictor of Glioblastoma Multiforme Growth-Studies Using SR-XRF Microscopy.

International Journal Of Molecular Sciences
Planeta, Karolina K; Setkowicz, Zuzanna Z; Czyzycki, Mateusz M; Janik-Olchawa, Natalia N; Ryszawy, Damian D; Janeczko, Krzysztof K; Simon, Rolf R; Baumbach, Tilo T; Chwiej, Joanna J
Publication Date: 2022-01-09

Variant appearance in text: KIT: T98g
PubMed Link: 35054889
Variant Present in the following documents:
  • Main text
  • ijms-23-00703.pdf
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Altered Elemental Distribution in Male Rat Brain Tissue as a Predictor of Glioblastoma Multiforme Growth-Studies Using SR-XRF Microscopy.

International Journal Of Molecular Sciences
Planeta, Karolina K; Setkowicz, Zuzanna Z; Czyzycki, Mateusz M; Janik-Olchawa, Natalia N; Ryszawy, Damian D; Janeczko, Krzysztof K; Simon, Rolf R; Baumbach, Tilo T; Chwiej, Joanna J
Publication Date: 2022-01-09

Variant appearance in text: KIT: T98g
PubMed Link: 35054889
Variant Present in the following documents:
  • Main text
  • ijms-23-00703.pdf
View BVdb publication page



Phytochemicals from Indian Ethnomedicines: Promising Prospects for the Management of Oxidative Stress and Cancer.

Antioxidants (Basel, Switzerland)
Fatima, Nishat N; Baqri, Syed Shabihe Raza SSR; Alsulimani, Ahmad A; Fagoonee, Sharmila S; Slama, Petr P; Kesari, Kavindra Kumar KK; Roychoudhury, Shubhadeep S; Haque, Shafiul S
Publication Date: 2021-10-13

Variant appearance in text: CD117: T98G
PubMed Link: 34679741
Variant Present in the following documents:
  • Main text
  • antioxidants-10-01606.pdf
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Novel Insights into the Antagonistic Effects of Losartan against Angiotensin II/AGTR1 Signaling in Glioblastoma Cells.

Cancers
Panza, Salvatore S; Malivindi, Rocco R; Caruso, Amanda A; Russo, Umberto U; Giordano, Francesca F; Győrffy, Balázs B; Gelsomino, Luca L; De Amicis, Francesca F; Barone, Ines I; Conforti, Francesca Luisa FL; Giordano, Cinzia C; Bonofiglio, Daniela D; Catalano, Stefania S; Andò, Sebastiano S
Publication Date: 2021-09-10

Variant appearance in text: KIT: T98G
PubMed Link: 34572782
Variant Present in the following documents:
  • Main text
  • cancers-13-04555.pdf
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Alectinib treatment improves photodynamic therapy in cancer cell lines of different origin.

Bmc Cancer
Gillissen, Bernhard B; Richter, Antje A; Essmann, Frank F; Kemmner, Wolfgang W
Publication Date: 2021-08-30

Variant appearance in text: KIT: T98G
PubMed Link: 34461853
Variant Present in the following documents:
  • 12885_2021_Article_8667.pdf
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Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

Stem Cell Research & Therapy
Fan, Xiaoqing X; Yang, Haoran H; Zhao, Chenggang C; Hu, Lizhu L; Wang, Delong D; Wang, Ruiting R; Fang, Zhiyou Z; Chen, Xueran X
Publication Date: 2021-02-04

Variant appearance in text: CD117: T98G
PubMed Link: 33541421
Variant Present in the following documents:
  • 13287_2021_Article_2175.pdf
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Recent advances in drug delivery systems for targeting cancer stem cells.

Acta Pharmaceutica Sinica. B
Duan, Hongxia H; Liu, Yanhong Y; Gao, Zhonggao Z; Huang, Wei W
Publication Date: 2021-01

Variant appearance in text: CD117: T98G
PubMed Link: 33532180
Variant Present in the following documents:
  • Main text
View BVdb publication page



A ruthenium(II)-curcumin compound modulates NRF2 expression balancing the cancer cell death/survival outcome according to p53 status.

Journal Of Experimental & Clinical Cancer Research : Cr
Garufi, Alessia A; Baldari, Silvia S; Pettinari, Riccardo R; Gilardini Montani, Maria Saveria MS; D'Orazi, Valerio V; Pistritto, Giuseppa G; Crispini, Alessandra A; Giorno, Eugenia E; Toietta, Gabriele G; Marchetti, Fabio F; Cirone, Mara M; D'Orazi, Gabriella G
Publication Date: 2020-06-30

Variant appearance in text: KIT: T98G
PubMed Link: 32605658
Variant Present in the following documents:
  • Main text
  • 13046_2020_Article_1628.pdf
View BVdb publication page



Marrubium vulgare L.: A Phytochemical and Pharmacological Overview.

Molecules (Basel, Switzerland)
Aćimović, Milica M; Jeremić, Katarina K; Salaj, Nebojša N; Gavarić, Neda N; Kiprovski, Biljana B; Sikora, Vladimir V; Zeremski, Tijana T
Publication Date: 2020-06-24

Variant appearance in text: KIT: T98G
PubMed Link: 32599693
Variant Present in the following documents:
  • Main text
View BVdb publication page



Angiogenesis in human brain tumors: screening of drug response through a patient-specific cell platform for personalized therapy.

Scientific Reports
Guarnaccia, Laura L; Navone, Stefania Elena SE; Trombetta, Elena E; Cordiglieri, Chiara C; Cherubini, Alessandro A; Crisà, Francesco Maria FM; Rampini, Paolo P; Miozzo, Monica M; Fontana, Laura L; Caroli, Manuela M; Locatelli, Marco M; Riboni, Laura L; Campanella, Rolando R; Marfia, Giovanni G
Publication Date: 2018-06-08

Variant appearance in text: CD117: T98G
PubMed Link: 29884885
Variant Present in the following documents:
  • Main text
  • 41598_2018_Article_27116.pdf
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Assessment of citalopram and escitalopram on neuroblastoma cell lines. Cell toxicity and gene modulation.

Oncotarget
Sakka, Laurent L; Delétage, Nathalie N; Chalus, Maryse M; Aissouni, Youssef Y; Sylvain-Vidal, Valérie V; Gobron, Stéphane S; Coll, Guillaume G
Publication Date: 2017-06-27

Variant appearance in text: KIT: T98G
PubMed Link: 28467792
Variant Present in the following documents:
  • oncotarget-08-42789.pdf
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Targeting oncomiRNAs and mimicking tumor suppressor miRNAs: Νew trends in the development of miRNA therapeutic strategies in oncology (Review).

International Journal Of Oncology
Gambari, Roberto R; Brognara, Eleonora E; Spandidos, Demetrios A DA; Fabbri, Enrica E
Publication Date: 2016-07

Variant appearance in text: KIT: T98G
PubMed Link: 27175518
Variant Present in the following documents:
  • Main text
View BVdb publication page



Targeting the AKT pathway: Repositioning HIV protease inhibitors as radiosensitizers.

The Indian Journal Of Medical Research
Goda, Jayant S JS; Pachpor, Tejaswini T; Basu, Trinanjan T; Chopra, Supriya S; Gota, Vikram V
Publication Date: 2016-02

Variant appearance in text: KIT: T98G
PubMed Link: 27121513
Variant Present in the following documents:
  • IJMR-143-145.pdf
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Combined PDGFR and HDAC Inhibition Overcomes PTEN Disruption in Chordoma.

Plos One
Lee, Dae-Hee DH; Zhang, Ying Y; Kassam, Amin B AB; Park, Myung-Jin MJ; Gardner, Paul P; Prevedello, Daniel D; Henry, Stephanie S; Horbinski, Craig C; Beumer, Jan H JH; Tawbi, Hussein H; Williams, Brian J BJ; Shaffrey, Mark E ME; Egorin, Merrill J MJ; Abounader, Roger R; Park, Deric M DM
Publication Date: 2015

Variant appearance in text: KIT: T98G
PubMed Link: 26247786
Variant Present in the following documents:
  • Main text
View BVdb publication page



Fgf9 inhibition of meiotic differentiation in spermatogonia is mediated by Erk-dependent activation of Nodal-Smad2/3 signaling and is antagonized by Kit Ligand.

Cell Death & Disease
Tassinari, V V; Campolo, F F; Cesarini, V V; Todaro, F F; Dolci, S S; Rossi, P P
Publication Date: 2015-03-12

Variant appearance in text: CD117: T98G
PubMed Link: 25766327
Variant Present in the following documents:
  • Main text
  • cddis201556a.pdf
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FAM96A is a novel pro-apoptotic tumor suppressor in gastrointestinal stromal tumors.

International Journal Of Cancer
Schwamb, Bettina B; Pick, Robert R; Fernández, Sara Beatriz Mateus SB; Völp, Kirsten K; Heering, Jan J; Dötsch, Volker V; Bösser, Susanne S; Jung, Jennifer J; Beinoraviciute-Kellner, Rasa R; Wesely, Josephine J; Zörnig, Inka I; Hammerschmidt, Matthias M; Nowak, Matthias M; Penzel, Roland R; Zatloukal, Kurt K; Joos, Stefan S; Rieker, Ralf Joachim RJ; Agaimy, Abbas A; Söder, Stephan S; Reid-Lombardo, K Marie KM; Kendrick, Michael L ML; Bardsley, Michael R MR; Hayashi, Yujiro Y; Asuzu, David T DT; Syed, Sabriya A SA; Ordog, Tamas T; Zörnig, Martin M
Publication Date: 2015-09-15

Variant appearance in text: KIT: T98G
PubMed Link: 25716227
Variant Present in the following documents:
  • Main text
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Targeting class IA PI3K isoforms selectively impairs cell growth, survival, and migration in glioblastoma.

Plos One
Höland, Katrin K; Boller, Danielle D; Hagel, Christian C; Dolski, Silvia S; Treszl, András A; Pardo, Olivier E OE; Cwiek, Paulina P; Salm, Fabiana F; Leni, Zaira Z; Shepherd, Peter R PR; Styp-Rekowska, Beata B; Djonov, Valentin V; von Bueren, André O AO; Frei, Karl K; Arcaro, Alexandre A
Publication Date: 2014

Variant appearance in text: KIT: T98G
PubMed Link: 24718026
Variant Present in the following documents:
  • pone.0094132.pdf
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The Effect of Z-Ligustilide on the Mobility of Human Glioblastoma T98G Cells.

Plos One
Yin, Jun J; Wang, Chengyuan C; Mody, Aaron A; Bao, Lin L; Hung, Shen-Hsiu SH; Svoronos, Spyros A SA; Tseng, Yiider Y
Publication Date: 2013

Variant appearance in text: KIT: T98G
PubMed Link: 23805245
Variant Present in the following documents:
  • Main text
  • pone.0066598.pdf
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PPARγ agonists regulate the expression of stemness and differentiation genes in brain tumour stem cells.

British Journal Of Cancer
Pestereva, E E; Kanakasabai, S S; Bright, J J JJ
Publication Date: 2012-05-08

Variant appearance in text: KIT: T98G
PubMed Link: 22531638
Variant Present in the following documents:
  • Main text
View BVdb publication page



Tegaserod in the treatment of constipation-predominant irritable bowel syndrome. Do the risks outweigh the benefits?

Naunyn-Schmiedeberg'S Archives Of Pharmacology
Wood, Peter P
Publication Date: 2012-01

Variant appearance in text: KIT: T98G
PubMed Link: 21969099
Variant Present in the following documents:
  • 210_2012_Article_736.pdf
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Clinical and experimental applications of sodium phenylbutyrate.

Drugs In R&D
Iannitti, Tommaso T; Palmieri, Beniamino B
Publication Date: 2011-09-01

Variant appearance in text: CD117: T98G
PubMed Link: 21902286
Variant Present in the following documents:
  • Main text
View BVdb publication page



Activation of p53 by nutlin-3a induces apoptosis and cellular senescence in human glioblastoma multiforme.

Plos One
Villalonga-Planells, Ruth R; Coll-Mulet, Llorenç L; Martínez-Soler, Fina F; Castaño, Esther E; Acebes, Juan-Jose JJ; Giménez-Bonafé, Pepita P; Gil, Joan J; Tortosa, Avelina A
Publication Date: 2011-04-05

Variant appearance in text: KIT: T98G
PubMed Link: 21483692
Variant Present in the following documents:
  • Main text
  • pone.0018588.pdf
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Characterization of the amplicon on chromosomal segment 4q12 in glioblastoma multiforme.

Neuro-Oncology
Holtkamp, Nikola N; Ziegenhagen, Nicolas N; Malzer, Elke E; Hartmann, Christian C; Giese, Alf A; von Deimling, Andreas A
Publication Date: 2007-07

Variant appearance in text: KIT: T98G
PubMed Link: 17504929
Variant Present in the following documents:
  • Main text
View BVdb publication page