KIT c.1118A>G ;(p.Y373C)

Variant ID: 4-55575592-A-G

NM_000222.2(KIT):c.1118A>G;(p.Y373C)

This variant was identified in 10 publications

View GRCh38 version.




Publications:


Comparative kinase and cancer cell panel profiling of kinase inhibitors approved for clinical use from 2018 to 2020.

Frontiers In Oncology
Kooijman, Jeffrey J JJ; van Riel, Wilhelmina E WE; Dylus, Jelle J; Prinsen, Martine B W MBW; Grobben, Yvonne Y; de Bitter, Tessa J J TJJ; van Doornmalen, Antoon M AM; Melis, Janneke J T M JJTM; Uitdehaag, Joost C M JCM; Narumi, Yugo Y; Kawase, Yusuke Y; de Roos, Jeroen A D M JADM; Willemsen-Seegers, Nicole N; Zaman, Guido J R GJR
Publication Date: 2022

Variant appearance in text: KIT: Y373C
PubMed Link: 36185300
Variant Present in the following documents:
  • Table_4.xlsx, sheet 1
View BVdb publication page



A full-proteome, interaction-specific characterization of mutational hotspots across human cancers.

Genome Research
Chen, Siwei S; Liu, Yuan Y; Zhang, Yingying Y; Wierbowski, Shayne D SD; Lipkin, Steven M SM; Wei, Xiaomu X; Yu, Haiyuan H
Publication Date: 2022-01

Variant appearance in text: KIT: Y373C
PubMed Link: 34963661
Variant Present in the following documents:
  • supp_gr.275437.121_Supplementary_Table_1.xlsx, sheet 3
View BVdb publication page



Therapeutic Actionability of Circulating Cell-Free DNA Alterations in Carcinoma of Unknown Primary.

Jco Precision Oncology
Kato, Shumei S; Weipert, Caroline C; Gumas, Sophia S; Okamura, Ryosuke R; Lee, Suzanna S; Sicklick, Jason K JK; Saam, Jennifer J; Kurzrock, Razelle R
Publication Date: 2021

Variant appearance in text: KIT: Y373C
PubMed Link: 34778692
Variant Present in the following documents:
  • po-5-po.21.00011.pdf
View BVdb publication page



Therapeutic Actionability of Circulating Cell-Free DNA Alterations in Carcinoma of Unknown Primary.

Jco Precision Oncology
Kato, Shumei S; Weipert, Caroline C; Gumas, Sophia S; Okamura, Ryosuke R; Lee, Suzanna S; Sicklick, Jason K JK; Saam, Jennifer J; Kurzrock, Razelle R
Publication Date: 2021

Variant appearance in text: KIT: Y373C
PubMed Link: 34778692
Variant Present in the following documents:
  • po-5-po.21.00011.pdf
View BVdb publication page



Molecular correlates and therapeutic targets in T cell-inflamed versus non-T cell-inflamed tumors across cancer types.

Genome Medicine
Bao, Riyue R; Stapor, Daniel D; Luke, Jason J JJ
Publication Date: 2020-10-27

Variant appearance in text: KIT: Y373C
PubMed Link: 33106165
Variant Present in the following documents:
  • 13073_2020_787_MOESM1_ESM.xlsx, sheet 9
View BVdb publication page



Potential of modern circulating cell-free DNA diagnostic tools for detection of specific tumour cells in clinical practice.

Biochemia Medica
Gašperšič, Jernej J; Videtič Paska, Alja A
Publication Date: 2020-10-15

Variant appearance in text: KIT: 1118A>G; Y373C
PubMed Link: 32774122
Variant Present in the following documents:
  • bm-30-3-030504-S1.pdf
View BVdb publication page



Integrative omics analyses broaden treatment targets in human cancer.

Genome Medicine
Sengupta, Sohini S; Sun, Sam Q SQ; Huang, Kuan-Lin KL; Oh, Clara C; Bailey, Matthew H MH; Varghese, Rajees R; Wyczalkowski, Matthew A MA; Ning, Jie J; Tripathi, Piyush P; McMichael, Joshua F JF; Johnson, Kimberly J KJ; Kandoth, Cyriac C; Welch, John J; Ma, Cynthia C; Wendl, Michael C MC; Payne, Samuel H SH; Fenyö, David D; Townsend, Reid R RR; Dipersio, John F JF; Chen, Feng F; Ding, Li L
Publication Date: 2018-07-27

Variant appearance in text: KIT: Y373C
PubMed Link: 30053901
Variant Present in the following documents:
  • 13073_2018_564_MOESM2_ESM.xlsx, sheet 19
  • 13073_2018_564_MOESM2_ESM.xlsx, sheet 8
View BVdb publication page



Oncogene mutational analysis in Chinese gastrointestinal stromal tumor patients.

Oncotargets And Therapy
Chen, Qiong Q; Li, Rong R; Zhang, Zhi-Gao ZG; Deng, Qiao-Ting QT; Li, Kun K; Wang, Hao H; Yang, Xue-Xi XX; Wu, Ying-Song YS
Publication Date: 2018

Variant appearance in text: KIT: Y373C
PubMed Link: 29719410
Variant Present in the following documents:
  • Main text
  • ott-11-2279.pdf
View BVdb publication page



Next generation MUT-MAP, a high-sensitivity high-throughput microfluidics chip-based mutation analysis panel.

Plos One
Schleifman, Erica B EB; Tam, Rachel R; Patel, Rajesh R; Tsan, Alison A; Sumiyoshi, Teiko T; Fu, Ling L; Desai, Rupal R; Schoenbrunner, Nancy N; Myers, Thomas W TW; Bauer, Keith K; Smith, Edward E; Raja, Rajiv R
Publication Date: 2014

Variant appearance in text: KIT: Y373C
PubMed Link: 24658394
Variant Present in the following documents:
  • pone.0090761.pdf
View BVdb publication page



Genotyping and genomic profiling of non-small-cell lung cancer: implications for current and future therapies.

Journal Of Clinical Oncology : Official Journal Of The American Society Of Clinical Oncology
Li, Tianhong T; Kung, Hsing-Jien HJ; Mack, Philip C PC; Gandara, David R DR
Publication Date: 2013-03-10

Variant appearance in text: KIT: Y373C
PubMed Link: 23401433
Variant Present in the following documents:
  • Main text
View BVdb publication page



Oncogene Mutation Survey in MPNST Cell Lines Enhances the Dominant Role of Hyperactive Ras in NF1 Associated Pro-Survival and Malignancy.

Translational Oncogenomics
Sun, Daochun D; Tainsky, Michael A MA; Haddad, Ramsi R
Publication Date: 2012

Variant appearance in text: KIT: Y373C
PubMed Link: 22346343
Variant Present in the following documents:
  • Main text
  • tog-5-2012-001.pdf
View BVdb publication page