KIT c.1675_1676delinsTG ;(p.V559C)

Variant ID: 4-55593609-GT-TG

NM_000222.2(KIT):c.1675_1676delinsTG;(p.V559C)

This variant was identified in 7 publications

View GRCh38 version.




Publications:


Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Publication Date: 2021

Variant appearance in text: KIT: V559C
PubMed Link: 34630336
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association
Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H
Publication Date: 2020-07

Variant appearance in text: KIT: V559C
PubMed Link: 32107691
Variant Present in the following documents:
  • 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12
View BVdb publication page



The mutational landscape of mucosal melanoma.

Seminars In Cancer Biology
Nassar, Kelsey W KW; Tan, Aik Choon AC
Publication Date: 2020-04

Variant appearance in text: KIT: V559C
PubMed Link: 31655118
Variant Present in the following documents:
  • Main text
View BVdb publication page



Lack of Response to Imatinib in Melanoma Carrying Rare KIT Mutation p.T632I.

Case Reports In Oncology
Orlova, Kristina V KV; Yanus, Grigory A GA; Aleksakhina, Svetlana N SN; Venina, Aigul R AR; Iyevleva, Aglaya G AG; Demidov, Lev V LV; Imyanitov, Evgeny N EN
Publication Date: 2019

Variant appearance in text: KIT: V559C
PubMed Link: 31043947
Variant Present in the following documents:
  • cro-0012-0109-s01.pdf
View BVdb publication page



Computational analysis reveals histotype-dependent molecular profile and actionable mutation effects across cancers.

Genome Medicine
Heim, Daniel D; Montavon, Grégoire G; Hufnagl, Peter P; Müller, Klaus-Robert KR; Klauschen, Frederick F
Publication Date: 2018-11-15

Variant appearance in text: KIT: V559C
PubMed Link: 30442178
Variant Present in the following documents:
  • 13073_2018_591_MOESM4_ESM.xlsx, sheet 1
View BVdb publication page



Phase II Study of Nilotinib in Melanoma Harboring KIT Alterations Following Progression to Prior KIT Inhibition.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Carvajal, Richard D RD; Lawrence, Donald P DP; Weber, Jeffrey S JS; Gajewski, Thomas F TF; Gonzalez, Rene R; Lutzky, Jose J; O'Day, Steven J SJ; Hamid, Omid O; Wolchok, Jedd D JD; Chapman, Paul B PB; Sullivan, Ryan J RJ; Teitcher, Jerrold B JB; Ramaiya, Nikhil N; Giobbie-Hurder, Anita A; Antonescu, Cristina R CR; Heinrich, Michael C MC; Bastian, Boris C BC; Corless, Christopher L CL; Fletcher, Jonathan A JA; Hodi, F Stephen FS
Publication Date: 2015-05-15

Variant appearance in text: KIT: V559C
PubMed Link: 25695690
Variant Present in the following documents:
  • Main text
View BVdb publication page



KIT as a therapeutic target in metastatic melanoma.

Jama
Carvajal, Richard D RD; Antonescu, Cristina R CR; Wolchok, Jedd D JD; Chapman, Paul B PB; Roman, Ruth-Ann RA; Teitcher, Jerrold J; Panageas, Katherine S KS; Busam, Klaus J KJ; Chmielowski, Bartosz B; Lutzky, Jose J; Pavlick, Anna C AC; Fusco, Anne A; Cane, Lauren L; Takebe, Naoko N; Vemula, Swapna S; Bouvier, Nancy N; Bastian, Boris C BC; Schwartz, Gary K GK
Publication Date: 2011-06-08

Variant appearance in text: KIT: V559C
PubMed Link: 21642685
Variant Present in the following documents:
  • Main text
View BVdb publication page