KIT c.1961T>C ;(p.V654A)

Variant ID: 4-55594258-T-C

NM_000222.2(KIT):c.1961T>C;(p.V654A)

This variant was identified in 216 publications

View GRCh38 version.




Publications:


Precision Oncology in Gastrointestinal Stromal Tumors.

Current Oncology (Toronto, Ont.)
Mechahougui, Hiba H; Michael, Montemurro M; Friedlaender, Alex A
Publication Date: 2023-04-30

Variant appearance in text: KIT: V654A
PubMed Link: 37232809
Variant Present in the following documents:
  • curroncol-30-00351.pdf
View BVdb publication page



Role and mechanistic actions of protein kinase inhibitors as an effective drug target for cancer and COVID.

Archives Of Microbiology
Narayanan, J J; Tamilanban, T T; Kumar, P Senthil PS; Guru, Ajay A; Muthupandian, Saravanan S; Kathiravan, M K MK; Arockiaraj, Jesu J
Publication Date: 2023-05-17

Variant appearance in text: KIT: V654A
PubMed Link: 37193831
Variant Present in the following documents:
  • 203_2023_Article_3559.pdf
View BVdb publication page



Emerging Targeted Therapeutic Strategies to Overcome Imatinib Resistance of Gastrointestinal Stromal Tumors.

International Journal Of Molecular Sciences
Masucci, Maria Teresa MT; Motti, Maria Letizia ML; Minopoli, Michele M; Di Carluccio, Gioconda G; Carriero, Maria Vincenza MV
Publication Date: 2023-03-23

Variant appearance in text: KIT: V654A
PubMed Link: 37046997
Variant Present in the following documents:
  • Main text
  • ijms-24-06026.pdf
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Development of Highly Sensitive Digital Droplet PCR for Detection of cKIT Mutations in Circulating Free DNA That Mediate Resistance to TKI Treatment for Gastrointestinal Stromal Tumor (GIST).

International Journal Of Molecular Sciences
Rassner, Michael M; Waldeck, Silvia S; Follo, Marie M; Jilg, Stefanie S; Philipp, Ulrike U; Jolic, Martina M; Wehrle, Julius J; Jost, Philipp J PJ; Peschel, Christian C; Illert, Anna Lena AL; Duyster, Justus J; Scherer, Florian F; von Bubnoff, Nikolas N
Publication Date: 2023-03-12

Variant appearance in text: KIT: V654A
PubMed Link: 36982486
Variant Present in the following documents:
  • Main text
  • ijms-24-05411.pdf
View BVdb publication page



Genomics-Driven Precision Medicine in Pediatric Solid Tumors.

Cancers
Suthapot, Praewa P; Chiangjong, Wararat W; Chaiyawat, Parunya P; Choochuen, Pongsakorn P; Pruksakorn, Dumnoensun D; Sangkhathat, Surasak S; Hongeng, Suradej S; Anurathapan, Usanarat U; Chutipongtanate, Somchai S
Publication Date: 2023-02-23

Variant appearance in text: KIT: V654A
PubMed Link: 36900212
Variant Present in the following documents:
  • Main text
View BVdb publication page



Activity of Anlotinib in the Second-Line Therapy of Metastatic Gastrointestinal Stromal Tumors: A Prospective, Multicenter, In Vitro Study.

The Oncologist
Zhou, Yongjian Y; Zeng, Chunling C; Sun, Xiaofeng X; Zhang, Jun J; Qu, Hongyan H; Zhang, Xinhua X; Zhou, Ye Y; Liu, Zimin Z; Wu, Xiaojun X; Wu, Xin X; Jiao, Xuelong X; Shen, Lin L; Zhou, Yanbing Y; Wang, Yuexiang Y; Li, Jian J
Publication Date: 2023-02-13

Variant appearance in text: KIT: V654A
PubMed Link: 36779523
Variant Present in the following documents:
  • Main text
  • oyac271.pdf
View BVdb publication page



Synergistic targeting of DNA-PK and KIT signaling pathways in KIT mutant acute myeloid leukemia.

Molecular & Cellular Proteomics : Mcp
Murray, Heather C HC; Miller, Kasey K; Brzozowski, Joshua S JS; Kahl, Richard G S RGS; Smith, Nathan D ND; Humphrey, Sean J SJ; Dun, Matthew D MD; Verrills, Nicole M NM
Publication Date: 2023-01-19

Variant appearance in text: KIT: V654A
PubMed Link: 36682716
Variant Present in the following documents:
  • main.pdf
View BVdb publication page



Identification of Thiazolo[5,4-b]pyridine Derivatives as c-KIT Inhibitors for Overcoming Imatinib Resistance.

Cancers
Nam, Yunju Y; Kim, Chan C; Han, Junghee J; Ryu, SeongShick S; Cho, Hanna H; Song, Chiman C; Kim, Nam Doo ND; Kim, Namkyoung N; Sim, Taebo T
Publication Date: 2022-12-26

Variant appearance in text: KIT: V654A
PubMed Link: 36612139
Variant Present in the following documents:
  • Main text
  • cancers-15-00143.pdf
View BVdb publication page



Escalation of radiotherapy dose in large locally advanced drug-resistant gastrointestinal stromal tumors by multi-shell simultaneous integrated boost intensity-modulated technique: a feasibility study.

Radiation Oncology (London, England)
Cui, Haixia H; Li, Ying Y; Huang, Wei W; Lu, Wenli W; Yi, Xin X
Publication Date: 2022-12-28

Variant appearance in text: KIT: V654A
PubMed Link: 36578008
Variant Present in the following documents:
  • Main text
  • 13014_2022_Article_2179.pdf
View BVdb publication page



Targeting the FGF/FGFR axis and its co-alteration allies.

Esmo Open
Uehara, Y Y; Ikeda, S S; Kim, K H KH; Lim, H J HJ; Adashek, J J JJ; Persha, H E HE; Okamura, R R; Lee, S S; Sicklick, J K JK; Kato, S S; Kurzrock, R R
Publication Date: 2022-11-28

Variant appearance in text: KIT: V654A
PubMed Link: 36455506
Variant Present in the following documents:
  • Main text
  • mmc1.pdf
  • main.pdf
View BVdb publication page



Plasma Sequencing for Patients with GIST-Limitations and Opportunities in an Academic Setting.

Cancers
Falkenhorst, Johanna J; Grunewald, Susanne S; Krzeciesa, Dawid D; Herold, Thomas T; Ketzer, Julia J; Christoff, Miriam M; Hamacher, Rainer R; Kostbade, Karina K; Treckmann, Jürgen J; Köster, Johannes J; Farzaliyev, Farhad F; Fletcher, Benjamin Samulon BS; Dieckmann, Nils N; Kaths, Moritz M; Mühlenberg, Thomas T; Schildhaus, Hans-Ulrich HU; Bauer, Sebastian S
Publication Date: 2022-11-09

Variant appearance in text: KIT: V654A
PubMed Link: 36428589
Variant Present in the following documents:
  • Main text
  • cancers-14-05496.pdf
View BVdb publication page



Molecular targeted therapy for anticancer treatment.

Experimental & Molecular Medicine
Min, Hye-Young HY; Lee, Ho-Young HY
Publication Date: 2022-10

Variant appearance in text: KIT: V654A
PubMed Link: 36224343
Variant Present in the following documents:
  • Main text
  • 12276_2022_Article_864.pdf
View BVdb publication page



Protein tyrosine kinase inhibitor resistance in malignant tumors: molecular mechanisms and future perspective.

Signal Transduction And Targeted Therapy
Yang, Yang Y; Li, Shuo S; Wang, Yujiao Y; Zhao, Yi Y; Li, Qiu Q
Publication Date: 2022-09-17

Variant appearance in text: KIT: V654A
PubMed Link: 36115852
Variant Present in the following documents:
  • Main text
  • 41392_2022_Article_1168.pdf
View BVdb publication page



Clonal hematopoiesis is not significantly associated with COVID-19 disease severity.

Blood
Zhou, Yifan Y; Shalhoub, Ruba R; Rogers, Stephanie N SN; Yu, Shiqin S; Gu, Muxin M; Fabre, Margarete A MA; Quiros, Pedro M PM; Shin, Tae-Hoon TH; Diangson, Arch A; Deng, Wenhan W; Anand, Shubha S; Lu, Wenhua W; Cullen, Matthew M; Godfrey, Anna L AL; Preller, Jacobus J; Hadjadj, Jerome J; Jouanguy, Emmanuelle E; Cobat, Aurélie A; Abel, Laurent L; Rieux-Laucat, Frederic F; Terrier, Benjamin B; Fischer, Alain A; Novik, Lara L; Gordon, Ingelise J IJ; Strom, Larisa L; Gaudinski, Martin R MR; Lisco, Andrea A; Sereti, Irini I; Gniadek, Thomas J TJ; Biondi, Andrea A; Bonfanti, Paolo P; Imberti, Luisa L; Dalgard, Clifton L CL; Zhang, Yu Y; Dobbs, Kerry K; Su, Helen C HC; Notarangelo, Luigi D LD; Wu, Colin O CO; Openshaw, Peter J M PJM; Semple, Malcolm G MG; Mallat, Ziad Z; Baillie, Kenneth K; Dunbar, Cynthia E CE; Vassiliou, George S GS
Publication Date: 2022-10-06

Variant appearance in text: KIT: V654A
PubMed Link: 35839449
Variant Present in the following documents:
  • mmc1.pdf
View BVdb publication page



Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis.

Nature Genetics
Kar, Siddhartha P SP; Quiros, Pedro M PM; Gu, Muxin M; Jiang, Tao T; Mitchell, Jonathan J; Langdon, Ryan R; Iyer, Vivek V; Barcena, Clea C; Vijayabaskar, M S MS; Fabre, Margarete A MA; Carter, Paul P; Petrovski, Slavé S; Burgess, Stephen S; Vassiliou, George S GS
Publication Date: 2022-08

Variant appearance in text: KIT: V654A
PubMed Link: 35835912
Variant Present in the following documents:
  • 41588_2022_1121_MOESM3_ESM.xlsx, sheet 3
View BVdb publication page



AACR Project GENIE: 100,000 Cases and Beyond.

Cancer Discovery
Pugh, Trevor J TJ; Bell, Jonathan L JL; Bruce, Jeff P JP; Doherty, Gary J GJ; Galvin, Matthew M; Green, Michelle F MF; Hunter-Zinck, Haley H; Kumari, Priti P; Lenoue-Newton, Michele L ML; Li, Marilyn M MM; Lindsay, James J; Mazor, Tali T; Ovalle, Andrea A; Sammut, Stephen-John SJ; Schultz, Nikolaus N; Yu, Thomas V TV; Sweeney, Shawn M SM; Bernard, Brady B; ,
Publication Date: 2022-09-02

Variant appearance in text: KIT: V654A
PubMed Link: 35819403
Variant Present in the following documents:
  • cd-21-1547_supplementary_table_1_suppst1.xlsx, sheet 1
View BVdb publication page



Efficacy and safety of ripretinib in patients with KIT-altered metastatic melanoma.

Esmo Open
Janku, F F; Bauer, S S; Shoumariyeh, K K; Jones, R L RL; Spreafico, A A; Jennings, J J; Psoinos, C C; Meade, J J; Ruiz-Soto, R R; Chi, P P
Publication Date: 2022-08

Variant appearance in text: KIT: V654A
PubMed Link: 35753087
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Integrated genomic analyses of acral and mucosal melanomas nominate novel driver genes.

Genome Medicine
Wang, Meng M; Banik, Ishani I; Shain, A Hunter AH; Yeh, Iwei I; Bastian, Boris C BC
Publication Date: 2022-06-16

Variant appearance in text: KIT: V654A
PubMed Link: 35706047
Variant Present in the following documents:
  • 13073_2022_1068_MOESM4_ESM.xlsx, sheet 1
View BVdb publication page



Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma.

Nature Communications
Gounder, Mrinal M MM; Agaram, Narasimhan P NP; Trabucco, Sally E SE; Robinson, Victoria V; Ferraro, Richard A RA; Millis, Sherri Z SZ; Krishnan, Anita A; Lee, Jessica J; Attia, Steven S; Abida, Wassim W; Drilon, Alexander A; Chi, Ping P; Angelo, Sandra P D' SP; Dickson, Mark A MA; Keohan, Mary Lou ML; Kelly, Ciara M CM; Agulnik, Mark M; Chawla, Sant P SP; Choy, Edwin E; Chugh, Rashmi R; Meyer, Christian F CF; Myer, Parvathi A PA; Moore, Jessica L JL; Okimoto, Ross A RA; Pollock, Raphael E RE; Ravi, Vinod V; Singh, Arun S AS; Somaiah, Neeta N; Wagner, Andrew J AJ; Healey, John H JH; Frampton, Garrett M GM; Venstrom, Jeffrey M JM; Ross, Jeffrey S JS; Ladanyi, Marc M; Singer, Samuel S; Brennan, Murray F MF; Schwartz, Gary K GK; Lazar, Alexander J AJ; Thomas, David M DM; Maki, Robert G RG; Tap, William D WD; Ali, Siraj M SM; Jin, Dexter X DX
Publication Date: 2022-06-15

Variant appearance in text: KIT: V654A
PubMed Link: 35705558
Variant Present in the following documents:
  • 41467_2022_30496_MOESM2_ESM.xls, sheet 1
View BVdb publication page



Construction and validation of an immunoediting-based optimized neoantigen load (ioTNL) model to predict the response and prognosis of immune checkpoint therapy in various cancers.

Aging
Su, Xiaofan X; Jin, Haoxuan H; Wang, Jiaqian J; Lu, Huiping H; Gu, Tiantian T; Gao, Zhibo Z; Li, Manxiang M
Publication Date: 2022-05-25

Variant appearance in text: KIT: 1961T>C; V654A
PubMed Link: 35613927
Variant Present in the following documents:
  • aging-14-204101-s004.xlsx, sheet 1
View BVdb publication page



Molecular Portrait of GISTs Associated With Clinicopathological Features: A Retrospective Study With Molecular Analysis by a Custom 9-Gene Targeted Next-Generation Sequencing Panel.

Frontiers In Genetics
Qian, Haoran H; Yan, Na N; Hu, Xiaotong X; Jiang, Junchang J; Cao, Zhengzheng Z; Shen, Dan D
Publication Date: 2022

Variant appearance in text: KIT: 1961T>C
PubMed Link: 35547262
Variant Present in the following documents:
  • Main text
  • fgene-13-864499.pdf
  • DataSheet1.xlsx, sheet 1
View BVdb publication page



Circulating Tumor DNA Mutations in Progressive Gastrointestinal Stromal Tumors Identify Biomarkers of Treatment Resistance and Uncover Potential Therapeutic Strategies.

Frontiers In Oncology
Ko, Tun Kiat TK; Lee, Elizabeth E; Ng, Cedric Chuan-Young CC; Yang, Valerie Shiwen VS; Farid, Mohamad M; Teh, Bin Tean BT; Chan, Jason Yongsheng JY; Somasundaram, Nagavalli N
Publication Date: 2022

Variant appearance in text: KIT: 1961T>C
PubMed Link: 35273917
Variant Present in the following documents:
  • Main text
  • fonc-12-840843.pdf
View BVdb publication page



The impact of whole genome and transcriptome analysis (WGTA) on predictive biomarker discovery and diagnostic accuracy of advanced malignancies.

The Journal Of Pathology. Clinical Research
Tessier-Cloutier, Basile B; Grewal, Jasleen K JK; Jones, Martin R MR; Pleasance, Erin E; Shen, Yaoqing Y; Cai, Ellen E; Dunham, Chris C; Hoang, Lynn L; Horst, Basil B; Huntsman, David G DG; Ionescu, Diana D; Karnezis, Anthony N AN; Lee, Anna F AF; Lee, Cheng Han CH; Lee, Tae Hoon TH; Twa, David Dw DD; Mungall, Andrew J AJ; Mungall, Karen K; Naso, Julia R JR; Ng, Tony T; Schaeffer, David F DF; Sheffield, Brandon S BS; Skinnider, Brian B; Smith, Tyler T; Williamson, Laura L; Zhong, Ellia E; Regier, Dean A DA; Laskin, Janessa J; Marra, Marco A MA; Gilks, C Blake CB; Jones, Steven Jm SJ; Yip, Stephen S
Publication Date: 2022-07

Variant appearance in text: KIT: 1961T>C; Val654Ala; rs121913523
PubMed Link: 35257510
Variant Present in the following documents:
  • CJP2-8-395-s002.xlsx, sheet 1
View BVdb publication page



Systematic review and meta-analysis of genomic alterations in acral melanoma.

Pigment Cell & Melanoma Research
Broit, Natasa N; Johansson, Peter A PA; Rodgers, Chloe B CB; Walpole, Sebastian T ST; Hayward, Nicholas K NK; Pritchard, Antonia L AL
Publication Date: 2022-05

Variant appearance in text: KIT: V654A
PubMed Link: 35229492
Variant Present in the following documents:
  • PCMR-35-369-s003.xlsx, sheet 6
  • PCMR-35-369-s003.xlsx, sheet 12
View BVdb publication page



The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

Nature Cancer
Tamborero, David D; Dienstmann, Rodrigo R; Rachid, Maan Haj MH; Boekel, Jorrit J; Lopez-Fernandez, Adria A; Jonsson, Markus M; Razzak, Ali A; Braña, Irene I; De Petris, Luigi L; Yachnin, Jeffrey J; Baird, Richard D RD; Loriot, Yohann Y; Massard, Christophe C; Martin-Romano, Patricia P; Opdam, Frans F; Schlenk, Richard F RF; Vernieri, Claudio C; Masucci, Michele M; Villalobos, Xenia X; Chavarria, Elena E; , ; Balmaña, Judith J; Apolone, Giovanni G; Caldas, Carlos C; Bergh, Jonas J; Ernberg, Ingemar I; Fröhling, Stefan S; Garralda, Elena E; Karlsson, Claes C; Tabernero, Josep J; Voest, Emile E; Rodon, Jordi J; Lehtiö, Janne J
Publication Date: 2022-02

Variant appearance in text: KIT: Val654Ala
PubMed Link: 35221333
Variant Present in the following documents:
  • 43018_2022_332_MOESM3_ESM.xlsx, sheet 1
View BVdb publication page



Nintedanib overcomes drug resistance from upregulation of FGFR signalling and imatinib-induced KIT mutations in gastrointestinal stromal tumours.

Molecular Oncology
Liu, Juan J; Gao, Jingjing J; Wang, Aoli A; Jiang, Zongru Z; Qi, Shuang S; Qi, Ziping Z; Liu, Feiyang F; Yu, Kailin K; Cao, Jiangyan J; Chen, Cheng C; Hu, Chen C; Wu, Hong H; Wang, Li L; Wang, Wenchao W; Liu, Qingsong Q; Liu, Jing J
Publication Date: 2022-04

Variant appearance in text: KIT: V654A
PubMed Link: 35194937
Variant Present in the following documents:
  • Main text
  • MOL2-16-1761.pdf
View BVdb publication page



Clinical Impact of Prospective Whole Genome Sequencing in Sarcoma Patients.

Cancers
Schipper, Luuk J LJ; Monkhorst, Kim K; Samsom, Kris G KG; Bosch, Linda J W LJW; Snaebjornsson, Petur P; van Boven, Hester H; Roepman, Paul P; van der Kolk, Lizet E LE; van Houdt, Winan J WJ; van der Graaf, Winette T A WTA; Meijer, Gerrit A GA; Voest, Emile E EE
Publication Date: 2022-01-16

Variant appearance in text: KIT: Val654Ala
PubMed Link: 35053600
Variant Present in the following documents:
  • Main text
  • cancers-14-00436.pdf
View BVdb publication page



Clinical Impact of Prospective Whole Genome Sequencing in Sarcoma Patients.

Cancers
Schipper, Luuk J LJ; Monkhorst, Kim K; Samsom, Kris G KG; Bosch, Linda J W LJW; Snaebjornsson, Petur P; van Boven, Hester H; Roepman, Paul P; van der Kolk, Lizet E LE; van Houdt, Winan J WJ; van der Graaf, Winette T A WTA; Meijer, Gerrit A GA; Voest, Emile E EE
Publication Date: 2022-01-16

Variant appearance in text: KIT: Val654Ala
PubMed Link: 35053600
Variant Present in the following documents:
  • Main text
  • cancers-14-00436.pdf
View BVdb publication page



Broad spectrum of regorafenib activity on mutant KIT and absence of clonal selection in gastrointestinal stromal tumor (GIST): correlative analysis from the GRID trial.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association
Jeffers, Michael M; Kappeler, Christian C; Kuss, Iris I; Beckmann, Georg G; Mehnert, Daniel H DH; Fredebohm, Johannes J; Teufel, Michael M
Publication Date: 2022-05

Variant appearance in text: KIT: V654A
PubMed Link: 35050442
Variant Present in the following documents:
  • Main text
  • 10120_2021_Article_1274.pdf
View BVdb publication page



Preclinical model-based evaluation of Imatinib resistance induced by KIT mutations and its overcoming strategies in gastrointestinal stromal tumor (GIST).

American Journal Of Translational Research
Zhao, Qian Q; Zhang, Cheng C; Qi, Changsong C; Yang, Jing J; Chen, Yang Y; Ge, Sai S; Shen, Lin L; Gao, Jing J; Li, Jian J
Publication Date: 2021

Variant appearance in text: KIT: V654A
PubMed Link: 35035701
Variant Present in the following documents:
  • Main text
View BVdb publication page



Pancreatic Cancer-Related Mutational Burden Is Not Increased in a Patient Cohort With Clinically Severe Chronic Pancreatitis.

Clinical And Translational Gastroenterology
Cowan, Robert W RW; Pratt, Erica D ED; Kang, Jin Muk JM; Zhao, Jun J; Wilhelm, Joshua J JJ; Abdulla, Muhamad M; Qiao, Edmund M EM; Brennan, Luke P LP; Ulintz, Peter J PJ; Bellin, Melena D MD; Rhim, Andrew D AD
Publication Date: 2021-11-18

Variant appearance in text: KIT: 1961T>C; Val654Ala; rs121913523
PubMed Link: 34797250
Variant Present in the following documents:
  • ct9-12-e00431-s006.xlsx, sheet 1
View BVdb publication page



Rearrangement-mediated cis-regulatory alterations in advanced patient tumors reveal interactions with therapy.

Cell Reports
Zhang, Yiqun Y; Chen, Fengju F; Pleasance, Erin E; Williamson, Laura L; Grisdale, Cameron J CJ; Titmuss, Emma E; Laskin, Janessa J; Jones, Steven J M SJM; Cortes-Ciriano, Isidro I; Marra, Marco A MA; Creighton, Chad J CJ
Publication Date: 2021-11-16

Variant appearance in text: KIT: 1961T>C; Val654Ala
PubMed Link: 34788622
Variant Present in the following documents:
  • NIHMS1757901-supplement-2.xlsx, sheet 3
View BVdb publication page



Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Publication Date: 2021

Variant appearance in text: KIT: V654A
PubMed Link: 34630336
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



Clinical Activity of Ripretinib in Patients with Advanced Gastrointestinal Stromal Tumor Harboring Heterogeneous KIT/PDGFRA Mutations in the Phase III INVICTUS Study.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Bauer, Sebastian S; Heinrich, Michael C MC; George, Suzanne S; Zalcberg, John R JR; Serrano, César C; Gelderblom, Hans H; Jones, Robin L RL; Attia, Steven S; D'Amato, Gina G; Chi, Ping P; Reichardt, Peter P; Meade, Julie J; Su, Ying Y; Ruiz-Soto, Rodrigo R; Blay, Jean-Yves JY; von Mehren, Margaret M; Schöffski, Patrick P
Publication Date: 2021-12-01

Variant appearance in text: KIT: V654A
PubMed Link: 34503977
Variant Present in the following documents:
  • Main text
  • 6333.pdf
View BVdb publication page



Combined Inhibition of AKT and KIT Restores Expression of Programmed Cell Death 4 (PDCD4) in Gastrointestinal Stromal Tumor.

Cancers
Kozinova, Marya M; Joshi, Shalina S; Ye, Shuai S; Belinsky, Martin G MG; Sharipova, Dinara D; Farma, Jeffrey M JM; Reddy, Sanjay S SS; Litwin, Samuel S; Devarajan, Karthik K; Campos, Alex Rosa AR; Yu, Yi Y; Schwartz, Brian B; von Mehren, Margaret M; Rink, Lori L
Publication Date: 2021-07-23

Variant appearance in text: KIT: V654A
PubMed Link: 34359600
Variant Present in the following documents:
  • Main text
  • cancers-13-03699.pdf
View BVdb publication page



Inhibition of PI3K and MAPK pathways along with KIT inhibitors as a strategy to overcome drug resistance in gastrointestinal stromal tumors.

Plos One
Gupta, Anu A; Ma, Shuang S; Che, Kepeng K; Pobbati, Ajaybabu V AV; Rubin, Brian P BP
Publication Date: 2021

Variant appearance in text: KIT: V654A
PubMed Link: 34324512
Variant Present in the following documents:
  • Main text
  • pone.0252689.pdf
View BVdb publication page



Early and Next-Generation KIT/PDGFRA Kinase Inhibitors and the Future of Treatment for Advanced Gastrointestinal Stromal Tumor.

Frontiers In Oncology
Bauer, Sebastian S; George, Suzanne S; von Mehren, Margaret M; Heinrich, Michael C MC
Publication Date: 2021

Variant appearance in text: KIT: V654A
PubMed Link: 34322383
Variant Present in the following documents:
  • Main text
View BVdb publication page



Guideline-Adherent Clinical Validation of a Comprehensive 170-Gene DNA/RNA Panel for Determination of Small Variants, Copy Number Variations, Splice Variants, and Fusions on a Next-Generation Sequencing Platform in the CLIA Setting.

Frontiers In Genetics
Boyle, Theresa A TA; Mondal, Ashis K AK; Saeed-Vafa, Daryoush D; Ananth, Sudha S; Ahluwalia, Pankaj P; Kothapalli, Ravi R; Chaubey, Alka A; Roberts, Evans E; Qin, Dahui D; Magliocco, Anthony M AM; Rojiani, Amyn M AM; Kolhe, Ravindra R
Publication Date: 2021

Variant appearance in text: KIT: V654A
PubMed Link: 34093633
Variant Present in the following documents:
  • Main text
  • fgene-12-503830.pdf
View BVdb publication page



Current Status and Prospects of Immunotherapy for Gynecologic Melanoma.

Journal Of Personalized Medicine
Anko, Mayuka M; Kobayashi, Yusuke Y; Banno, Kouji K; Aoki, Daisuke D
Publication Date: 2021-05-12

Variant appearance in text: KIT: V654A
PubMed Link: 34065883
Variant Present in the following documents:
  • Main text
View BVdb publication page



Ripretinib for the treatment of advanced gastrointestinal stromal tumor.

Therapeutic Advances In Gastroenterology
Zalcberg, John R JR
Publication Date: 2021

Variant appearance in text: KIT: V654A
PubMed Link: 33948116
Variant Present in the following documents:
  • Main text
View BVdb publication page