Publications:

Refinement of evolutionary medicine predictions based on clinical evidence for the manifestations of Mendelian diseases.

Scientific Reports

Šimčíková, Daniela D; Heneberg, Petr P

Publication Date: 2019-12-09

Variant appearance in text: KIT: D792E

PubMed Link: 31819097

Variant Present in the following documents:

• 41598_2019_54976_MOESM2_ESM.xlsx, sheet 8

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Hotspot mutations in KIT receptor differentially modulate its allosterically coupled conformational dynamics: impact on activation and drug sensitivity.

Plos Computational Biology

Chauvot de Beauchêne, Isaure I; Allain, Ariane A; Panel, Nicolas N; Laine, Elodie E; Trouvé, Alain A; Dubreuil, Patrice P; Tchertanov, Luba L

Publication Date: 2014-07

Variant appearance in text: KIT: D792E

PubMed Link: 25079768

Variant Present in the following documents:

• Main text
• pcbi.1003749.pdf

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Allosteric communication across the native and mutated KIT receptor tyrosine kinase.

Plos Computational Biology

Laine, Elodie E; Auclair, Christian C; Tchertanov, Luba L

Publication Date: 2012

Variant appearance in text: KIT: D792E

PubMed Link: 22927810

Variant Present in the following documents:

• Main text
• pcbi.1002661.pdf

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