KIT c.*217G>A

Variant ID: 4-55604940-G-A

NM_000222.2(KIT):c.*217G>A

This variant was identified in 17 publications

View GRCh38 version.




Publications:


miR-221/222 as biomarkers and targets for therapeutic intervention on cancer and other diseases: A systematic review.

Molecular Therapy. Nucleic Acids
Di Martino, Maria Teresa MT; Arbitrio, Mariamena M; Caracciolo, Daniele D; Cordua, Alessia A; Cuomo, Onofrio O; Grillone, Katia K; Riillo, Caterina C; Caridà, Giulio G; Scionti, Francesca F; Labanca, Caterina C; Romeo, Caterina C; Siciliano, Maria Anna MA; D'Apolito, Maria M; Napoli, Cristina C; Montesano, Martina M; Farenza, Valentina V; Uppolo, Valentina V; Tafuni, Michele M; Falcone, Federica F; D'Aquino, Giuseppe G; Calandruccio, Natale Daniele ND; Luciano, Francesco F; Pensabene, Licia L; Tagliaferri, Pierosandro P; Tassone, Pierfrancesco P
Publication Date: 2022-03-08

Variant appearance in text: rs17084733
PubMed Link: 35282417
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Analysis on Value of Applying Serum miR-144 and miR-221 Levels in Diagnosing Atherosclerosis.

Journal Of Healthcare Engineering
Zhang, Jianxiu J; Cao, Qian Q; Zhang, Zhenying Z; Du, Chenguang C; Wang, Lizhong L
Publication Date: 2022

Variant appearance in text: rs17084733
PubMed Link: 35126910
Variant Present in the following documents:
  • JHE2022-2261854.pdf
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Strategies to Modulate MicroRNA Functions for the Treatment of Cancer or Organ Injury.

Pharmacological Reviews
Lee, Tae Jin TJ; Yuan, Xiaoyi X; Kerr, Keith K; Yoo, Ji Young JY; Kim, Dong H DH; Kaur, Balveen B; Eltzschig, Holger K HK
Publication Date: 2020-07

Variant appearance in text: rs17084733
PubMed Link: 32554488
Variant Present in the following documents:
  • Main text
View BVdb publication page



Effects of microRNAs polymorphism in cancer progression.

Medical Journal Of The Islamic Republic Of Iran
SiamiGorji, Simin S; Jorjani, Isa I; Tahamtan, Alireza A; Moradi, Abdolvahab A
Publication Date: 2020

Variant appearance in text: rs17084733
PubMed Link: 32284927
Variant Present in the following documents:
  • Main text
  • mjiri-34-3.pdf
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PGG.SNV: understanding the evolutionary and medical implications of human single nucleotide variations in diverse populations.

Genome Biology
Zhang, Chao C; Gao, Yang Y; Ning, Zhilin Z; Lu, Yan Y; Zhang, Xiaoxi X; Liu, Jiaojiao J; Xie, Bo B; Xue, Zhe Z; Wang, Xiaoji X; Yuan, Kai K; Ge, Xueling X; Pan, Yuwen Y; Liu, Chang C; Tian, Lei L; Wang, Yuchen Y; Lu, Dongsheng D; Hoh, Boon-Peng BP; Xu, Shuhua S
Publication Date: 2019-10-22

Variant appearance in text: rs17084733
PubMed Link: 31640808
Variant Present in the following documents:
  • 13059_2019_1838_MOESM3_ESM.xlsx, sheet 1
View BVdb publication page



The rs17084733 variant in the KIT 3' UTR disrupts a miR-221/222 binding site in gastrointestinal stromal tumour: a sponge-like mechanism conferring disease susceptibility.

Epigenetics
Ravegnini, Gloria G; Serrano, César C; Simeon, Vittorio V; Sammarini, Giulia G; Nannini, Margherita M; Roversi, Erica E; Urbini, Milena M; Ferrè, Fabrizio F; Ricci, Riccardo R; Tarantino, Giuseppe G; Pantaleo, Maria A MA; Hrelia, Patrizia P; Angelini, Sabrina S
Publication Date: 2019-06

Variant appearance in text: rs17084733
PubMed Link: 30983504
Variant Present in the following documents:
  • Main text
  • kepi-14-06-1595997.pdf
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Whole genome sequencing identifies high-impact variants in well-known pharmacogenomic genes.

The Pharmacogenomics Journal
Choi, Jihoon J; Tantisira, Kelan G KG; Duan, Qing Ling QL
Publication Date: 2019-04

Variant appearance in text: rs17084733
PubMed Link: 30214008
Variant Present in the following documents:
  • NIHMS1503453-supplement-3.xlsx, sheet 1
View BVdb publication page



Comprehensive assessment for miRNA polymorphisms in hepatocellular cancer risk: a systematic review and meta-analysis.

Bioscience Reports
Wang, Ben-Gang BG; Jiang, Li-Yue LY; Xu, Qian Q
Publication Date: 2018-10-31

Variant appearance in text: rs17084733
PubMed Link: 29976775
Variant Present in the following documents:
  • Main text
  • bsr-38-bsr20180712.pdf
View BVdb publication page



MicroRNA-Related Polymorphisms in Infectious Diseases-Tiny Changes With a Huge Impact on Viral Infections and Potential Clinical Applications.

Frontiers In Immunology
Ellwanger, Joel Henrique JH; Zambra, Francis Maria Báo FMB; Guimarães, Rafael Lima RL; Chies, José Artur Bogo JAB
Publication Date: 2018

Variant appearance in text: rs17084733
PubMed Link: 29963045
Variant Present in the following documents:
  • Main text
View BVdb publication page



Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes.

Oncotarget
Keerthikumar, Shivakumar S; Gangoda, Lahiru L; Liem, Michael M; Fonseka, Pamali P; Atukorala, Ishara I; Ozcitti, Cemil C; Mechler, Adam A; Adda, Christopher G CG; Ang, Ching-Seng CS; Mathivanan, Suresh S
Publication Date: 2015-06-20

Variant appearance in text: rs17084733
PubMed Link: 25944692
Variant Present in the following documents:
  • oncotarget-06-15375-s005.xlsx, sheet 2
View BVdb publication page



Transcriptome-wide analysis of UTRs in non-small cell lung cancer reveals cancer-related genes with SNV-induced changes on RNA secondary structure and miRNA target sites.

Plos One
Sabarinathan, Radhakrishnan R; Wenzel, Anne A; Novotny, Peter P; Tang, Xiaojia X; Kalari, Krishna R KR; Gorodkin, Jan J
Publication Date: 2014

Variant appearance in text: rs17084733
PubMed Link: 24416147
Variant Present in the following documents:
  • pone.0082699.s009.pdf
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miRNA-mediated relationships between Cis-SNP genotypes and transcript intensities in lymphocyte cell lines.

Plos One
Zhang, Wensheng W; Edwards, Andrea A; Zhu, Dongxiao D; Flemington, Erik K EK; Deininger, Prescott P; Zhang, Kun K
Publication Date: 2012

Variant appearance in text: rs17084733
PubMed Link: 22348086
Variant Present in the following documents:
  • Main text
  • pone.0031429.pdf
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A Variant in a MicroRNA complementary site in the 3' UTR of the KIT oncogene increases risk of acral melanoma.

Oncogene
Godshalk, S E SE; Paranjape, T T; Nallur, S S; Speed, W W; Chan, E E; Molinaro, A M AM; Bacchiocchi, A A; Hoyt, K K; Tworkoski, K K; Stern, D F DF; Sznol, M M; Ariyan, S S; Lazova, R R; Halaban, R R; Kidd, K K KK; Weidhaas, J B JB; Slack, F J FJ
Publication Date: 2011-03-31

Variant appearance in text: rs17084733
PubMed Link: 21119596
Variant Present in the following documents:
  • Main text
  • nihms243664.pdf
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MicroRNA binding site polymorphisms as biomarkers of cancer risk.

Expert Review Of Molecular Diagnostics
Pelletier, Cory C; Weidhaas, Joanne B JB
Publication Date: 2010-09

Variant appearance in text: rs17084733
PubMed Link: 20843204
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic determinants of hair and eye colours in the Scottish and Danish populations.

Bmc Genetics
Mengel-From, Jonas J; Wong, Terence H TH; Morling, Niels N; Rees, Jonathan L JL; Jackson, Ian J IJ
Publication Date: 2009-12-30

Variant appearance in text: rs17084733
PubMed Link: 20042077
Variant Present in the following documents:
  • Main text
  • 1471-2156-10-88.pdf
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MicroRNAs: tools for cancer diagnostics.

Gut
Paranjape, T T; Slack, F J FJ; Weidhaas, J B JB
Publication Date: 2009-11

Variant appearance in text: rs17084733
PubMed Link: 19834118
Variant Present in the following documents:
  • Main text
View BVdb publication page



The role of microRNA genes in papillary thyroid carcinoma.

Proceedings Of The National Academy Of Sciences Of The United States Of America
He, Huiling H; Jazdzewski, Krystian K; Li, Wei W; Liyanarachchi, Sandya S; Nagy, Rebecca R; Volinia, Stefano S; Calin, George A GA; Liu, Chang-Gong CG; Franssila, Kaarle K; Suster, Saul S; Kloos, Richard T RT; Croce, Carlo M CM; de la Chapelle, Albert A
Publication Date: 2005-12-27

Variant appearance in text: rs17084733
PubMed Link: 16365291
Variant Present in the following documents:
  • Main text
View BVdb publication page