Publications:

---

Emerging roles of PLCγ1 in endothelial biology.

Science Signaling

Chen, Dongying D; Simons, Michael M

Publication Date: 2021-08-03

Variant appearance in text: VEGFR2: Y1175F

PubMed Link: 34344833

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Temporal Dynamics of VEGFA-Induced VEGFR2/FAK Co-Localization Depend on SHB.

Cells

Pietilä, Ilkka I; Van Mourik, Djenolan D; Tamelander, Andreas A; Kriz, Vitezslav V; Claesson-Welsh, Lena L; Tengholm, Anders A; Welsh, Michael M

Publication Date: 2019-12-15

Variant appearance in text: VEGFR2: Y1175F

PubMed Link: 31847469

Variant Present in the following documents:

• Main text
• cells-08-01645.pdf

View BVdb publication page

---

Comparison of the ligand-binding properties of fluorescent VEGF-A isoforms to VEGF receptor 2 in living cells and membrane preparations using NanoBRET.

British Journal Of Pharmacology

Peach, Chloe J CJ; Kilpatrick, Laura E LE; Woolard, Jeanette J; Hill, Stephen J SJ

Publication Date: 2019-09

Variant appearance in text: VEGFR2: Y1175F

PubMed Link: 31162634

Variant Present in the following documents:

• Main text
• BPH-176-3220.pdf

View BVdb publication page

---

Protein Phosphotyrosine Phosphatase 1B (PTP1B) in Calpain-dependent Feedback Regulation of Vascular Endothelial Growth Factor Receptor (VEGFR2) in Endothelial Cells: IMPLICATIONS IN VEGF-DEPENDENT ANGIOGENESIS AND DIABETIC WOUND HEALING.

The Journal Of Biological Chemistry

Zhang, Yixuan Y; Li, Qiang Q; Youn, Ji Youn JY; Cai, Hua H

Publication Date: 2017-01-13

Variant appearance in text: VEGFR2: Y1175F

PubMed Link: 27872190

Variant Present in the following documents:

• Main text

View BVdb publication page

---

VEGF-A isoforms program differential VEGFR2 signal transduction, trafficking and proteolysis.

Biology Open

Fearnley, Gareth W GW; Smith, Gina A GA; Abdul-Zani, Izma I; Yuldasheva, Nadira N; Mughal, Nadeem A NA; Homer-Vanniasinkam, Shervanthi S; Kearney, Mark T MT; Zachary, Ian C IC; Tomlinson, Darren C DC; Harrison, Michael A MA; Wheatcroft, Stephen B SB; Ponnambalam, Sreenivasan S

Publication Date: 2016-05-15

Variant appearance in text: VEGFR2: Y1175F

PubMed Link: 27044325

Variant Present in the following documents:

• Main text
• biolopen-5-017434.pdf

View BVdb publication page

---

AIP1 Expression in Tumor Niche Suppresses Tumor Progression and Metastasis.

Cancer Research

Ji, Weidong W; Li, Yonghao Y; He, Yun Y; Yin, Mingzhu M; Zhou, Huanjiao Jenny HJ; Boggon, Titus J TJ; Zhang, Haifeng H; Min, Wang W

Publication Date: 2015-09-01

Variant appearance in text: VEGFR2: Y1175F

PubMed Link: 26139244

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Molecular controls of arterial morphogenesis.

Circulation Research

Simons, Michael M; Eichmann, Anne A

Publication Date: 2015-05-08

Variant appearance in text: VEGFR2: Y1175F

PubMed Link: 25953926

Variant Present in the following documents:

• Main text

View BVdb publication page

---

PTP1b is a physiologic regulator of vascular endothelial growth factor signaling in endothelial cells.

Circulation

Lanahan, Anthony A AA; Lech, Diana D; Dubrac, Alexandre A; Zhang, Jiasheng J; Zhuang, Zhen W ZW; Eichmann, Anne A; Simons, Michael M

Publication Date: 2014-09-09

Variant appearance in text: VEGFR2: Y1175F

PubMed Link: 24982127

Variant Present in the following documents:

• Main text

View BVdb publication page

---

The docking protein FRS2α is a critical regulator of VEGF receptors signaling.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Chen, Pei-Yu PY; Qin, Lingfeng L; Zhuang, Zhen W ZW; Tellides, George G; Lax, Irit I; Schlessinger, Joseph J; Simons, Michael M

Publication Date: 2014-04-15

Variant appearance in text: VEGFR2: Y1175F

PubMed Link: 24706887

Variant Present in the following documents:

• Main text

View BVdb publication page

---

VEGF-VEGFR Signals in Health and Disease.

Biomolecules & Therapeutics

Shibuya, Masabumi M

Publication Date: 2014-01

Variant appearance in text: VEGFR: Y1175F

PubMed Link: 24596615

Variant Present in the following documents:

• Main text
• 1-9_bt22-1.pdf

View BVdb publication page

---

Vascular endothelial growth factor receptor-2 activates ADP-ribosylation factor 1 to promote endothelial nitric-oxide synthase activation and nitric oxide release from endothelial cells.

The Journal Of Biological Chemistry

Daher, Zeinab Z; Boulay, Pierre-Luc PL; Desjardins, Fanny F; Gratton, Jean-Philippe JP; Claing, Audrey A

Publication Date: 2010-08-06

Variant appearance in text: VEGFR: Y1175F

PubMed Link: 20529868

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Vascular endothelial growth factor (VEGF) receptor-2 tyrosine 1175 signaling controls VEGF-induced von Willebrand factor release from endothelial cells via phospholipase C-gamma 1- and protein kinase A-dependent pathways.

The Journal Of Biological Chemistry

Xiong, Yan Y; Huo, Yingqing Y; Chen, Chao C; Zeng, Huiyan H; Lu, Xiaofan X; Wei, Chaoliang C; Ruan, Changgeng C; Zhang, Xiaoyu X; Hu, Zhenqian Z; Shibuya, Masabumi M; Luo, Jincai J

Publication Date: 2009-08-28

Variant appearance in text: VEGFR2: Y1175F

PubMed Link: 19570985

Variant Present in the following documents:

• Main text

View BVdb publication page

---

New role for the protein tyrosine phosphatase DEP-1 in Akt activation and endothelial cell survival.

Molecular And Cellular Biology

Chabot, Catherine C; Spring, Kathleen K; Gratton, Jean-Philippe JP; Elchebly, Mounib M; Royal, Isabelle I

Publication Date: 2009-01

Variant appearance in text: VEGFR2: Y1175F

PubMed Link: 18936167

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Role of protein tyrosine phosphatase 1B in vascular endothelial growth factor signaling and cell-cell adhesions in endothelial cells.

Circulation Research

Nakamura, Yoshimasa Y; Patrushev, Nikolay N; Inomata, Hyoe H; Mehta, Dolly D; Urao, Norifumi N; Kim, Ha Won HW; Razvi, Masooma M; Kini, Vidisha V; Mahadev, Kalyankar K; Goldstein, Barry J BJ; McKinney, Ronald R; Fukai, Tohru T; Ushio-Fukai, Masuko M

Publication Date: 2008-05-23

Variant appearance in text: VEGFR2: Y1175F

PubMed Link: 18451337

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Regulating angiogenesis at the level of PtdIns-4,5-P2.

The Embo Journal

Im, Eunok E; Kazlauskas, Andrius A

Publication Date: 2006-05-17

Variant appearance in text: VEGFR2: Y1175F

PubMed Link: 16628216

Variant Present in the following documents:

• Main text

View BVdb publication page

---

A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells.

The Embo Journal

Takahashi, T T; Yamaguchi, S S; Chida, K K; Shibuya, M M

Publication Date: 2001-06-01

Variant appearance in text: KDR: Y1175F

PubMed Link: 11387210

Variant Present in the following documents:

• Main text

View BVdb publication page

---