Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma.
Proceedings Of The National Academy Of Sciences Of The United States Of America
Perry, Jennifer A JA; Kiezun, Adam A; Tonzi, Peter P; Van Allen, Eliezer M EM; Carter, Scott L SL; Baca, Sylvan C SC; Cowley, Glenn S GS; Bhatt, Ami S AS; Rheinbay, Esther E; Pedamallu, Chandra Sekhar CS; Helman, Elena E; Taylor-Weiner, Amaro A; McKenna, Aaron A; DeLuca, David S DS; Lawrence, Michael S MS; Ambrogio, Lauren L; Sougnez, Carrie C; Sivachenko, Andrey A; Walensky, Loren D LD; Wagle, Nikhil N; Mora, Jaume J; de Torres, Carmen C; Lavarino, Cinzia C; Dos Santos Aguiar, Simone S; Yunes, Jose Andres JA; Brandalise, Silvia Regina SR; Mercado-Celis, Gabriela Elisa GE; Melendez-Zajgla, Jorge J; Cárdenas-Cardós, Rocío R; Velasco-Hidalgo, Liliana L; Roberts, Charles W M CW; Garraway, Levi A LA; Rodriguez-Galindo, Carlos C; Gabriel, Stacey B SB; Lander, Eric S ES; Golub, Todd R TR; Orkin, Stuart H SH; Getz, Gad G; Janeway, Katherine A KA