KDR c.2852A>T ;(p.Y951F)

Variant ID: 4-55961088-T-A

NM_002253.2(KDR):c.2852A>T;(p.Y951F)

This variant was identified in 13 publications

View GRCh38 version.




Publications:


Syndecan-2 selectively regulates VEGF-induced vascular permeability.

Nature Cardiovascular Research
Corti, F F; Ristori, E E; Rivera-Molina, F F; Toomre, D D; Zhang, J J; Mihailovic, J J; Zhuang, Z W ZW; Simons, M M
Publication Date: 2022-05

Variant appearance in text: VEGFR2: Y951F
PubMed Link: 36212522
Variant Present in the following documents:
  • Main text
  • nihms-1796440.pdf
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Sphingolipids in Lung Pathology in the Coronavirus Disease Era: A Review of Sphingolipid Involvement in the Pathogenesis of Lung Damage.

Frontiers In Physiology
Khan, Saad A SA; Goliwas, Kayla F KF; Deshane, Jessy S JS
Publication Date: 2021

Variant appearance in text: VEGFR2: Y951F
PubMed Link: 34690821
Variant Present in the following documents:
  • Main text
  • fphys-12-760638.pdf
View BVdb publication page



Temporal Dynamics of VEGFA-Induced VEGFR2/FAK Co-Localization Depend on SHB.

Cells
Pietilä, Ilkka I; Van Mourik, Djenolan D; Tamelander, Andreas A; Kriz, Vitezslav V; Claesson-Welsh, Lena L; Tengholm, Anders A; Welsh, Michael M
Publication Date: 2019-12-15

Variant appearance in text: VEGFR2: Y951F
PubMed Link: 31847469
Variant Present in the following documents:
  • Main text
  • cells-08-01645.pdf
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Sphingosine-1-Phosphate Receptor 1 Activity Promotes Tumor Growth by Amplifying VEGF-VEGFR2 Angiogenic Signaling.

Cell Reports
Balaji Ragunathrao, Vijay Avin VA; Anwar, Mumtaz M; Akhter, Md Zahid MZ; Chavez, Alejandra A; Mao, De Yu Y; Natarajan, Viswanathan V; Lakshmikanthan, Sribalaji S; Chrzanowska-Wodnicka, Magdalena M; Dudek, Arkadiusz Z AZ; Claesson-Welsh, Lena L; Kitajewski, Jan K JK; Wary, Kishore K KK; Malik, Asrar B AB; Mehta, Dolly D
Publication Date: 2019-12-10

Variant appearance in text: VEGFR2: Y951F
PubMed Link: 31825830
Variant Present in the following documents:
  • Main text
View BVdb publication page



Comparison of the ligand-binding properties of fluorescent VEGF-A isoforms to VEGF receptor 2 in living cells and membrane preparations using NanoBRET.

British Journal Of Pharmacology
Peach, Chloe J CJ; Kilpatrick, Laura E LE; Woolard, Jeanette J; Hill, Stephen J SJ
Publication Date: 2019-09

Variant appearance in text: VEGFR2: Y951F
PubMed Link: 31162634
Variant Present in the following documents:
  • Main text
  • BPH-176-3220.pdf
View BVdb publication page



Signal transduction by vascular endothelial growth factor receptors.

Cold Spring Harbor Perspectives In Medicine
Koch, Sina S; Claesson-Welsh, Lena L
Publication Date: 2012-07

Variant appearance in text: VEGFR2: Y951F
PubMed Link: 22762016
Variant Present in the following documents:
  • Main text
View BVdb publication page



VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd.

The Journal Of Experimental Medicine
Sun, Zuyue Z; Li, Xiujuan X; Massena, Sara S; Kutschera, Simone S; Padhan, Narendra N; Gualandi, Laura L; Sundvold-Gjerstad, Vibeke V; Gustafsson, Karin K; Choy, Wing Wen WW; Zang, Guangxiang G; Quach, My M; Jansson, Leif L; Phillipson, Mia M; Abid, Md Ruhul MR; Spurkland, Anne A; Claesson-Welsh, Lena L
Publication Date: 2012-07-02

Variant appearance in text: VEGFR2: Y951F
PubMed Link: 22689825
Variant Present in the following documents:
  • Main text
View BVdb publication page



VEGFR2 translocates to the nucleus to regulate its own transcription.

Plos One
Domingues, Inês I; Rino, José J; Demmers, Jeroen A A JA; de Lanerolle, Primal P; Santos, Susana Constantino Rosa SC
Publication Date: 2011

Variant appearance in text: VEGFR2: Y951F
PubMed Link: 21980525
Variant Present in the following documents:
  • Main text
View BVdb publication page



Autocrine activity of soluble Flt-1 controls endothelial cell function and angiogenesis.

Vascular Cell
Ahmad, Shakil S; Hewett, Peter W PW; Al-Ani, Bahjat B; Sissaoui, Samir S; Fujisawa, Takeshi T; Cudmore, Melissa J MJ; Ahmed, Asif A
Publication Date: 2011-07-13

Variant appearance in text: VEGFR2: Y951F
PubMed Link: 21752276
Variant Present in the following documents:
  • 2045-824X-3-15.pdf
View BVdb publication page



Anchorage of VEGF to the extracellular matrix conveys differential signaling responses to endothelial cells.

The Journal Of Cell Biology
Chen, Tom T TT; Luque, Alfonso A; Lee, Sunyoung S; Anderson, Sean M SM; Segura, Tatiana T; Iruela-Arispe, M Luisa ML
Publication Date: 2010-02-22

Variant appearance in text: VEGFR2: Y951F
PubMed Link: 20176926
Variant Present in the following documents:
  • Main text
View BVdb publication page



TIMP-2 modulates VEGFR-2 phosphorylation and enhances phosphodiesterase activity in endothelial cells.

Laboratory Investigation; A Journal Of Technical Methods And Pathology
Lee, Seo-Jin SJ; Tsang, Patricia S PS; Diaz, Tere M TM; Wei, Bei-yang BY; Stetler-Stevenson, William George WG
Publication Date: 2010-03

Variant appearance in text: KDR: Y951F
PubMed Link: 20084057
Variant Present in the following documents:
  • nihms159578.pdf
View BVdb publication page



Vascular endothelial growth factor (VEGF) receptor-2 tyrosine 1175 signaling controls VEGF-induced von Willebrand factor release from endothelial cells via phospholipase C-gamma 1- and protein kinase A-dependent pathways.

The Journal Of Biological Chemistry
Xiong, Yan Y; Huo, Yingqing Y; Chen, Chao C; Zeng, Huiyan H; Lu, Xiaofan X; Wei, Chaoliang C; Ruan, Changgeng C; Zhang, Xiaoyu X; Hu, Zhenqian Z; Shibuya, Masabumi M; Luo, Jincai J
Publication Date: 2009-08-28

Variant appearance in text: VEGFR2: Y951F
PubMed Link: 19570985
Variant Present in the following documents:
  • Main text
View BVdb publication page



New role for the protein tyrosine phosphatase DEP-1 in Akt activation and endothelial cell survival.

Molecular And Cellular Biology
Chabot, Catherine C; Spring, Kathleen K; Gratton, Jean-Philippe JP; Elchebly, Mounib M; Royal, Isabelle I
Publication Date: 2009-01

Variant appearance in text: VEGFR2: Y951F
PubMed Link: 18936167
Variant Present in the following documents:
  • Main text
View BVdb publication page